Cell Organelles and Inclusions

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Questions and Answers

What is the primary function of microtubules in a cell?

  • To stabilize cell shape (correct)
  • To synthesize proteins
  • To store genetic information
  • To transport molecules across the cell membrane

Which of the following is NOT a type of inclusion in a cell?

  • Mitochondria (correct)
  • Melanin
  • Caroten
  • Glycogen

What is the name of the structure that microtubules extend from in a cell?

  • Centriole
  • Lysosome
  • Centrosome (correct)
  • Nucleus

Which of the following is an example of an exogenous pigment?

<p>Caroten (C)</p> Signup and view all the answers

What is the name of the protein subunits that make up microtubules?

<p>Tubulin (C)</p> Signup and view all the answers

What is the term for the temporary structures of a cell that can be observed under the light and electron microscope?

<p>Inclusions (D)</p> Signup and view all the answers

What is the function of kinesin-based transport in a cell?

<p>Transport of vesicles into the cell periphery (C)</p> Signup and view all the answers

What is the name of the structure that is composed of microtubules in different cell types?

<p>Axoneme (D)</p> Signup and view all the answers

What is the diameter of intermediate filaments?

<p>10-12nm (C)</p> Signup and view all the answers

Which of the following intermediate filaments is found in epithelial cells?

<p>Cytokeratin (A)</p> Signup and view all the answers

What is the function of pigment deposits in cells?

<p>Storage of metabolites (A)</p> Signup and view all the answers

Which of the following is an exogen pigment?

<p>Caroten (D)</p> Signup and view all the answers

What is the function of intermediate filaments in cells?

<p>Structural support (B)</p> Signup and view all the answers

Which of the following intermediate filaments is found in astrocytes?

<p>GFAP (A)</p> Signup and view all the answers

What is the characteristic of intermediate filaments compared to microtubules and actin filaments?

<p>Thinner than microtubules and thicker than actin filaments (D)</p> Signup and view all the answers

What is the purpose of resin embedding in microscopy?

<p>To preserve cell structure (C)</p> Signup and view all the answers

What is the main function of actin-binding proteins in microfilaments?

<p>To regulate the assembly of microfilaments and interactions with other filaments (D)</p> Signup and view all the answers

What is the composition of filaments in the cytoskeleton?

<p>G-actin monomers (A)</p> Signup and view all the answers

During which stage of the cell cycle do centrioles duplicate?

<p>During interphase (C)</p> Signup and view all the answers

What is the function of actin filaments in endocytosis and exocytosis?

<p>To form pseudopodia (A)</p> Signup and view all the answers

What is the structure of a centriole?

<p>9 microtubular triplets + 0 (D)</p> Signup and view all the answers

Which type of cells are more prone to accumulate lipofuscin granules?

<p>Long-living non-dividing cells (D)</p> Signup and view all the answers

What is the role of actin filaments in microvilli?

<p>To localize in microvilli (C)</p> Signup and view all the answers

What is the function of actin filaments during mitosis and cytokinesis?

<p>To influence the physical properties of the local cytoplasm (B)</p> Signup and view all the answers

What is the function of macrophages in relation to hemosiderin formation?

<p>Phagocytosing erythrocytes (C)</p> Signup and view all the answers

Which of the following is a characteristic of lipofuscin granules?

<p>Accumulated by-product of lysosomal degeneration (C)</p> Signup and view all the answers

What is the main function of microtubules in the cytoskeleton?

<p>To provide structural support and shape to the cell (C)</p> Signup and view all the answers

What is the role of melanocytes in the context of melanin?

<p>Producing melanin (C)</p> Signup and view all the answers

Which type of cells are known to have abundant lipid droplets?

<p>Cells of adrenal cortex (C)</p> Signup and view all the answers

What is the term for cytoplasmic structures or deposits filled with stored macromolecules?

<p>Cellular inclusions (A)</p> Signup and view all the answers

What is the primary function of glycogen in cells like hepatocytes and skeletal muscle cells?

<p>Storage of carbohydrates (C)</p> Signup and view all the answers

What is the name of the staining method used to visualize glycogen in hepatocytes?

<p>Periodic Acid Schiff staining (C)</p> Signup and view all the answers

In which cells can Reinke crystals be found?

<p>Leydig cells of testis (A)</p> Signup and view all the answers

What is the name of the crystals found in the apical cytoplasm of eosinophils and neutrophils?

<p>Secretion granules (B)</p> Signup and view all the answers

What is the term for the fluid component of the cytoplasm?

<p>Cytosol (D)</p> Signup and view all the answers

What is the name of the staining method used to visualize lipid droplets in cells?

<p>OsO4 staining (D)</p> Signup and view all the answers

In which cells can crystals be found in the lumen of the endoplasmic reticulum?

<p>Leydig cells of testis (A)</p> Signup and view all the answers

What is the term for the membranous structures found in the cytoplasm of cells?

<p>Organelles (B)</p> Signup and view all the answers

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Study Notes

Non-Membranous Organelles

  • Microtubules:
    • Composed of tubulin subunits
    • Oriented in arrays
    • Generally extend from the centrosome to the most peripheral extensions of the cell
    • Serve to stabilize cell shape
    • Form the tracks for kinesin-based transport of vesicles and organelles into the cell periphery
    • Form the tracks for dynein-based transport towards the cell nucleus
  • Microtubule organization:
    • Found in axonemes, cilia, flagellum, and basal bodies of cilia
    • Play a role in the formation of the mitotic spindle

Centrioles

  • Consist of 9 microtubular triplets
  • Found in centriole pairs
  • Each half of the centriole pair has a duplicated centriole pair during a cell's interphase
  • At the onset of mitosis, each centriole pair separates

Filaments

  • Actin filaments:
    • Composed of G-actin monomers
    • Regulated by actin-binding proteins
    • Play a role in pseudopode formation, endocytosis, and exocytosis
    • Involved in the movement of organelles in the cytoplasm
    • Localized in microvilli, intermediate junctions of epithelial cells, and during mitosis and cytokinesis
    • Form a dynamic network important for cell shape changes
  • Intermediate filaments:
    • Thicker than actin filaments, thinner than microtubules
    • Simple structure compared to the others
    • Found in various cell types, including epithelial cells, mesenchymal cells, muscle cells, astrocytes, and neurons
    • Composed of different proteins, such as cytokeratin, vimentin, desmin, and glial fibrillar acidic protein

Inclusions

  • Non-living structures
  • Pigments:
    • Endogenous pigments: melanin, hemosiderin, hemoglobin, lipofuscin, and caroten
    • Exogenous pigments: caroten, lipochrom, and carbon particles
  • Storage of metabolites:
    • Lipids (fat)
    • Glycogen
  • Crystals:
    • Found in cytoplasm or lumen of ER
    • Examples include guanin crystals, uric acid crystals, and Reinke crystals
  • Secretion granules:
    • Stored in the apical cytoplasm
    • Usually protein in nature
    • Examples include zymogen granules

Cell Components

  • Cytosol or cytoplasmic matrix:
    • The region between the cell membrane and organelles
  • Organelles:
    • A) Membrane-bounded organelles
    • Cell membrane

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