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What is the role of acetylcholine in the synaptic space?
What is the role of acetylcholine in the synaptic space?
What is the name of the structure that the spinal cord extends to?
What is the name of the structure that the spinal cord extends to?
How many segments does the spinal cord have?
How many segments does the spinal cord have?
What is the name of the part of the muscle fiber where acetylcholine receptors are found?
What is the name of the part of the muscle fiber where acetylcholine receptors are found?
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What is the result of Na ion entry into the muscle fiber?
What is the result of Na ion entry into the muscle fiber?
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What is the name of the structure that stores neurotransmitters such as acetylcholine?
What is the name of the structure that stores neurotransmitters such as acetylcholine?
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How many pairs of spinal nerves arise from each segment of the spinal cord?
How many pairs of spinal nerves arise from each segment of the spinal cord?
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What is the site where the spinal cord lies?
What is the site where the spinal cord lies?
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What is the location of the cerebellum?
What is the location of the cerebellum?
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What is the appearance of the cerebellum's outer surface?
What is the appearance of the cerebellum's outer surface?
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Which of the following best describes the arrangement of gray and white matter in the cerebellum?
Which of the following best describes the arrangement of gray and white matter in the cerebellum?
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What is the function of the cerebellum?
What is the function of the cerebellum?
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What is the name given to the white matter within the cerebellum due to its branching appearance?
What is the name given to the white matter within the cerebellum due to its branching appearance?
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Which of the following structures is responsible for the secretion of cerebrospinal fluid (CSF)?
Which of the following structures is responsible for the secretion of cerebrospinal fluid (CSF)?
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What is the name given to the spaces within the brain that contain cerebrospinal fluid?
What is the name given to the spaces within the brain that contain cerebrospinal fluid?
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Which of the following statements accurately describes the connection between the third ventricle and the fourth ventricle?
Which of the following statements accurately describes the connection between the third ventricle and the fourth ventricle?
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What is the primary ion present in excess outside the cell?
What is the primary ion present in excess outside the cell?
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What is maintained during a cell's state of rest without excitation?
What is maintained during a cell's state of rest without excitation?
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How do ions generally diffuse across the cell membrane?
How do ions generally diffuse across the cell membrane?
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What is the typical resting membrane potential in a nerve cell?
What is the typical resting membrane potential in a nerve cell?
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What factor primarily influences the movement of ions across the cell membrane?
What factor primarily influences the movement of ions across the cell membrane?
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What creates the intracellular negative potential in a resting cell?
What creates the intracellular negative potential in a resting cell?
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What is the term used to describe the combined effect of electrical and chemical forces on ion movement?
What is the term used to describe the combined effect of electrical and chemical forces on ion movement?
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What happens to ion flow when electrochemical equilibrium is reached?
What happens to ion flow when electrochemical equilibrium is reached?
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What happens when a single peripheral nerve is cut?
What happens when a single peripheral nerve is cut?
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What is the primary difference between visceral sensations and somatic sensations?
What is the primary difference between visceral sensations and somatic sensations?
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What is referred pain?
What is referred pain?
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What causes referred pain?
What causes referred pain?
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How do nerve fibers from the skin and internal organs converge in the spinal cord?
How do nerve fibers from the skin and internal organs converge in the spinal cord?
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Which of the following is NOT controlled by the autonomic nervous system?
Which of the following is NOT controlled by the autonomic nervous system?
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What type of muscle does the autonomic nervous system primarily control?
What type of muscle does the autonomic nervous system primarily control?
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Which of the following is TRUE about the autonomic nervous system?
Which of the following is TRUE about the autonomic nervous system?
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What is the primary function of the spinal cord in relation to the central nervous system?
What is the primary function of the spinal cord in relation to the central nervous system?
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Which structure connects the two hemispheres of the cerebrum?
Which structure connects the two hemispheres of the cerebrum?
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Which part of the brain is responsible for controlling the left side of the body?
Which part of the brain is responsible for controlling the left side of the body?
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What occurs when there is bleeding in one hemisphere of the brain?
What occurs when there is bleeding in one hemisphere of the brain?
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What structure is considered the largest part of the central nervous system?
What structure is considered the largest part of the central nervous system?
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How are motor movements and sensory sensations represented in the brain?
How are motor movements and sensory sensations represented in the brain?
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What are the main sections the brain is divided into?
What are the main sections the brain is divided into?
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Which of the following functions is NOT attributed to the brain?
Which of the following functions is NOT attributed to the brain?
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Study Notes
Electrical Potential Difference between Inside and Outside the Cell
- The main ions involved in the electrical potential difference between inside and outside the cell are sodium, potassium, and chlorine anions.
- Sodium is present in excess outside the cell, while potassium is present inside the cell.
- Ions are charged and cannot easily pass through the membrane, but they do so through their own channels.
Ionic Equilibrium: Electrochemical Potentials of Ions
- Ions inside and outside the cell are at certain concentrations at rest.
- The passage of ions from one medium to another depends on the permeability of the cell membrane and the type of electrical charge in the medium it will pass through.
- The cell membrane has different permeability properties to each ion, which is why ions diffuse from the high side to the lesser side.
- Both electrical and chemical potential play a role in the movement of an ion, and are together called electrochemical potentials.
- The flow of an ion from one chamber to the other is from where the electrochemical potential of the ion is high to the lower direction.
- When the ion flow stops between both compartments, the ion has reached electrochemical equilibrium.
Resting Membrane Potential
- If electrodes are inserted into and out of the cell in a nerve cell and connected to a potentiometer, there is a potential difference of -90 mV at rest.
- This potential difference arises from the different distribution of ions on both sides.
- It is an intracellular negative potential due to protein anions that cannot pass the membrane inside the cell.
Nerve Impulse Transmission
- When a nerve impulse from the brain and spinal cord reaches the end of the motor nerve extension, it causes acetylcholine, a neurotransmitter substance, to be released from the synaptic vesicles.
- Acetylcholine in the synaptic space combines with acetylcholine receptors in muscle fiber sarcolemma, increasing the permeability of the membrane to sodium ions.
- Na ion entry creates an action potential and depolarizes the membrane, leading to the release of calcium ions from the sarcoplasmic reticulum to the cytosol.
- Thus, muscle contraction is initiated.
Central Nervous System
- The central nervous system has two parts: the spinal cord (medulla spinalis) and the brain (encephalon).
Spinal Cord (Medulla Spinalis)
- The spinal cord lies within the spinal canal (canalis vertebralis).
- It is the continuation of the brain stem.
- The lower end of the spinal cord is like a cone (conus medullaris).
- The spinal cord has a transversally segmental structure, with 31 segments, and a pair of spinal nerves arise from each segment.
Brain (Encephalon)
- The brain is the largest part of the central nervous system and is in the skull.
- It can be divided into four major sub-sections: cerebrum (brain hemispheres), diencephalon (intermediate brain), truncus cerebri (brain stem), and cerebellum.
- The cerebrum consists of two cerebral hemispheres separated by a deep cleft with a longitudinal course.
- Each hemisphere controls the opposite side of the body.
- The cerebellum is located behind the medulla oblongata and pons, and provides muscle tone and balance, and the harmony of the muscles.
- Balance and proper posture are achieved with the senses coming from the muscles, joints, and hemisphere tracts.
Brain Cavities (Ventriculus Cerebri)
- There are four cavities filled with cerebrospinal fluid (CSF) within the entire brain compartments.
- These spaces, called ventricles, are lined with ependymal cells and are in contact with each other.
- The plexus choroideus is responsible for the secretion of liquor cerebrospinalis (cerebrospinal fluid) and is found in all ventricles.
Visceral Sensations
- Visceral sensations are the senses that come from internal organs.
- The nerves that transmit the visceral senses enter the medulla of the spinal cord from the posterior root, just like the somatic nerves.
- Visceral senses, unlike somatic senses, cannot be localized well (poor localization).
Referred Pain
- Referred pain is pain perceived at a location other than the site of the painful stimulus/origin.
- It is the result of a network of interconnecting sensory nerves that supplies many different tissues.
- When there is an injury at one site in the network, it is possible that when the signal is interpreted in the brain, signals are experienced in the surrounding nervous tissue.
Autonomous Nervous System
- The autonomic nervous system is a part of the peripheral nervous system and works independently, continuously, and involuntarily.
- It controls the contraction of smooth muscles, the secretion of glands, and the regulation of heart rhythms.
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Description
This quiz tests your understanding of the ionic balance between the inside and outside of a cell, including the role of sodium, potassium, and chlorine ions in maintaining the electrical potential difference. Learn about the movement of ions through channels in the cell membrane and how it affects the cell's resting state.