Plasma Membrane 3

What is the main function of cell junctions?

Allow for communication between neighboring cells

Which of the following is NOT a function of cell junctions?

Enable cell movement

In what way do cell junctions contribute to reducing stress placed upon cells?

By bonding cells together

Which statement best describes the purpose of the paracellular barrier in epithelia?

To regulate the passage of molecules between cells Signup and view all the answers

What does the term 'ground substance' refer to in the context of cell junctions?

The space between cells filled with fluid and proteins Signup and view all the answers

Why are cell junctions particularly abundant in tissues?

To maintain structural integrity and communication between cells Signup and view all the answers

Which type of junction is responsible for forming channel-like connections between cells?

Gap junctions Signup and view all the answers

In which tissue type are direct attachments between cells rare?

Connective tissues Signup and view all the answers

What is the function of cell-matrix junctions in epithelial tissues?

Anchoring cells to the basal lamina Signup and view all the answers

Which type of junction reinforces cell adhesion by linking the cytoskeletons of adjacent cells?

Desmosomes Signup and view all the answers

Which tissue type bears most of the mechanical stress in the interstitial matrix?

Connective tissues Signup and view all the answers

Which type of cell-matrix junction is responsible for connecting cells to the ECM via integrin proteins?

Hemidesmosomes Signup and view all the answers

What type of molecules can pass through GAP JUNCTIONS from cell to cell?

Ions and glucose Signup and view all the answers

Where are GAP JUNCTIONS located in the body?

Epithelial tissue, cardiac muscle, smooth muscle, and connective tissue Signup and view all the answers

Which proteins bridge cell-matrix interactions in TUNNEL cell-matrix anchoring junctions?

Integrins Signup and view all the answers

What activates INTEGRINS in cell-matrix interactions?

Binding to intracellular activator proteins Signup and view all the answers

What is the main function of ACTIN-LINKED CELL-MATRIX JUNCTIONS or focal adhesions?

Anchoring actin filaments in cells to the extracellular matrix Signup and view all the answers

Which of the following functions can be influenced by INTEGRINS through intracellular signals?

Migration and survival Signup and view all the answers

What is the main function of tight junctions?

Act as a diffusion barrier for macromolecules Signup and view all the answers

Which proteins make up tight junctions?

Claudin and occludin Signup and view all the answers

Where are tight junctions mostly located?

At the apical location in epithelial cells Signup and view all the answers

What is the function of cell-cell anchoring junctions?

Hold cells together under mechanical stress Signup and view all the answers

Which transmembrane adhesion proteins are involved in cell-cell anchoring junctions?

Cadherins Signup and view all the answers

What is the function of cadherins in cell-cell anchoring junctions?

Span the plasma membrane and link to the cytoskeleton Signup and view all the answers

What is the main function of adherens junctions?

Anchor actin filament bundles between cells Signup and view all the answers

Where are desmosomes primarily located?

In tissues that experience stress or stretch Signup and view all the answers

What is the structural difference between adherens junctions and desmosomes?

Desmosomes connect intermediate filaments while adherens junctions connect actin filaments Signup and view all the answers

In which type of tissues would you expect to find adherens junctions predominantly?

Epithelial and endothelial tissues Signup and view all the answers

What is the main role of desmosomes in tissues?

Provide anchorage for intermediate filaments and withstand mechanical stress Signup and view all the answers

What is the electron micrograph shown in the text depicting?

Desmosomes in the skin of a baby mouse Signup and view all the answers

What is the primary function of cell junctions in tissues?

Provide structural support and connection between cells Signup and view all the answers

Which type of junction is responsible for building up the paracellular barrier in epithelial tissues?

Tight junctions Signup and view all the answers

In which type of tissues are cell junctions particularly abundant?

Epithelial tissues Signup and view all the answers

What is the main role of integrins in cell-matrix interactions?

Anchor cells to the extracellular matrix Signup and view all the answers

Which function is NOT associated with cell junctions?

Enhancing genetic mutations Signup and view all the answers

Where are desmosomes primarily located in tissues?

Muscle tissues Signup and view all the answers

How do tight junctions contribute to reducing stress in tissues?

By holding cells together in tissues subjected to mechanical stress Signup and view all the answers

Which statement best describes the function of cadherins in cell-cell anchoring junctions?

Establishing strong structural connections between adjacent cells Signup and view all the answers

Where are desmosomes primarily located in the body?

Epidermis Signup and view all the answers

What is the role of claudin and occludin in tight junctions?

Form selective permeability barriers for paracellular transport Signup and view all the answers

In what type of tissues would you expect to find adherens junctions predominantly?

Heart Signup and view all the answers

What distinguishes adherens junctions from desmosomes in terms of their structure?

Presence of transmembrane adhesion proteins belonging to the cadherin family Signup and view all the answers

Which type of junction is responsible for forming direct attachments between cells?

Adherens junctions Signup and view all the answers

In which tissues would you expect to find HEIMDESMOSOMES predominantly?

Epithelial tissue Signup and view all the answers

Which type of junction is responsible for allowing small molecules and ions to pass between adjacent cells?

Gap junctions Signup and view all the answers

What is the main role of cell-matrix anchoring junctions?

Anchoring cells to the extracellular matrix Signup and view all the answers

Which cells are primarily responsible for producing the extracellular matrix in connective tissues?

Fibroblasts Signup and view all the answers

Where are tight junctions primarily located in the body?

Epithelial tissue Signup and view all the answers

What is the width of the gap in GAP JUNCTIONS that allows the passage of small hydrophilic molecules?

4-6 nm Signup and view all the answers

Which type of junction anchors actin filaments in cells to the extracellular matrix?

Focal Adhesions Signup and view all the answers

What is the main function of INTEGRINS in cell-matrix interactions?

Sense and respond to mechanical forces Signup and view all the answers

Which tissue type is NOT mentioned as containing GAP JUNCTIONS?

Nervous Tissue Signup and view all the answers

What do ACTIN-LINKED CELL-MATRIX JUNCTIONS primarily anchor in cells?

Actin Filaments Signup and view all the answers

Which aspect of cell behavior can be influenced by INTEGRINS through intracellular signals?

Cell Migration Signup and view all the answers

What is the main function of desmosomes in cell junctions?

Provide anchorage site for cytoskeleton Signup and view all the answers

Where are zonula adherens predominantly located within tissues?

Endothelial tissues Signup and view all the answers

Which type of cell-cell junction is especially abundant in tissues subject to significant stretching or stress?

Desmosomes Signup and view all the answers

What is the structural difference between zonula adherens and desmosomes?

Adhere to intermediate filaments Signup and view all the answers

Which type of cell junction provides mechanical strength to tissues that face a lot of stress or stretching?

Desmosomes Signup and view all the answers

What is the main function of cell junctions?

Anchor cells together and reduce stress Signup and view all the answers

Which function is NOT associated with cell junctions?

Promoting cell differentiation Signup and view all the answers

In what way do cell junctions contribute to reducing stress placed upon cells?

By anchoring cells together Signup and view all the answers

Which statement best describes the purpose of the paracellular barrier in epithelia?

To prevent movement of large molecules between cells Signup and view all the answers

What distinguishes adherens junctions from desmosomes?

Their interaction with actin filaments Signup and view all the answers

Where are gap junctions primarily located in tissues?

Along lateral surfaces of cells Signup and view all the answers

What is the main function of zonula adherens junctions?

Guide the organization of developing tissues Signup and view all the answers

Where are desmosomes primarily located?

Skin tissue Signup and view all the answers

Which type of cell junction is structurally similar to adherens junctions but connects intermediate filaments instead of actin filaments?

Desmosomes Signup and view all the answers

What is the main function of junctional complexes?

Provide mechanical strength to tissues Signup and view all the answers

Which type of cell junction is located more basal than tight junctions in epithelial and endothelial tissues?

Adherens junctions Signup and view all the answers

What is the primary role of adhesion belts or zonula adherens?

Guide the organization of developing tissues Signup and view all the answers

What proteins make up tight junctions?

Claudin and occludin Signup and view all the answers

Where are tight junctions mostly found in the body?

Urinary bladder and respiratory tract Signup and view all the answers

What is the primary function of desmosomes in cell junctions?

Anchor cells together and withstand mechanical stress Signup and view all the answers

Which type of tissue contains abundant anchoring junctions due to mechanical stress?

Muscular tissue Signup and view all the answers

What is the main role of CADHERINS in cell-cell anchoring junctions?

Transmit large forces between cells Signup and view all the answers

Where are adherens junctions predominantly located within tissues?

At the basolateral region Signup and view all the answers

What is the primary function of GAP JUNCTIONS?

Allow the passage of small hydrophobic molecules between cells Signup and view all the answers

Which type of junction anchors actin filaments in cells to the extracellular matrix?

Adherens Junctions Signup and view all the answers

What is a common function influenced by INTEGRINS through intracellular signals?

Blood clotting Signup and view all the answers

Where are focal adhesions primarily located?

Connective tissue Signup and view all the answers

Which type of junction allows action potentials to spread rapidly from cell to cell?

GAP JUNCTIONS Signup and view all the answers

What is the main purpose of TUNNEL CELL-MATRIX ANCHORING JUNCTIONS?

Bridge cell-matrix interactions Signup and view all the answers

Where are Lining of the intestines and epidermal covering of the skin primarily located?

Bone Signup and view all the answers

What is the main function of GAP JUNCTIONS?

Allowing small molecules and ions to pass between adjacent cells Signup and view all the answers

Which type of junction is especially abundant in tissues subject to significant stretching or stress?

Desmosomes Signup and view all the answers

Where would you NOT expect to find direct attachments between cells?

Adipose tissue Signup and view all the answers

What primarily anchors in ACTIN-LINKED CELL-MATRIX JUNCTIONS?

Cytoplasmic domains of cell-adhesion proteins Signup and view all the answers

Which type of tissues have cell-matrix anchoring junctions like HEMIDESMOSOMES?

Epithelial tissues Signup and view all the answers

Plasma Membrane 3

Questions and Answers

What is the main function of cell junctions?

Which of the following is NOT a function of cell junctions?

In what way do cell junctions contribute to reducing stress placed upon cells?

Which statement best describes the purpose of the paracellular barrier in epithelia?

What does the term 'ground substance' refer to in the context of cell junctions?

Why are cell junctions particularly abundant in tissues?

Which type of junction is responsible for forming channel-like connections between cells?

In which tissue type are direct attachments between cells rare?

What is the function of cell-matrix junctions in epithelial tissues?

Which type of junction reinforces cell adhesion by linking the cytoskeletons of adjacent cells?

Which tissue type bears most of the mechanical stress in the interstitial matrix?

Which type of cell-matrix junction is responsible for connecting cells to the ECM via integrin proteins?

What type of molecules can pass through GAP JUNCTIONS from cell to cell?

Where are GAP JUNCTIONS located in the body?

Which proteins bridge cell-matrix interactions in TUNNEL cell-matrix anchoring junctions?

What activates INTEGRINS in cell-matrix interactions?

What is the main function of ACTIN-LINKED CELL-MATRIX JUNCTIONS or focal adhesions?

Which of the following functions can be influenced by INTEGRINS through intracellular signals?

What is the main function of tight junctions?

Which proteins make up tight junctions?

Where are tight junctions mostly located?

What is the function of cell-cell anchoring junctions?

Which transmembrane adhesion proteins are involved in cell-cell anchoring junctions?

What is the function of cadherins in cell-cell anchoring junctions?

What is the main function of adherens junctions?

Where are desmosomes primarily located?

What is the structural difference between adherens junctions and desmosomes?

In which type of tissues would you expect to find adherens junctions predominantly?

What is the main role of desmosomes in tissues?

What is the electron micrograph shown in the text depicting?

What is the primary function of cell junctions in tissues?

Which type of junction is responsible for building up the paracellular barrier in epithelial tissues?

In which type of tissues are cell junctions particularly abundant?

What is the main role of integrins in cell-matrix interactions?

Which function is NOT associated with cell junctions?

Where are desmosomes primarily located in tissues?

How do tight junctions contribute to reducing stress in tissues?

Which statement best describes the function of cadherins in cell-cell anchoring junctions?

Where are desmosomes primarily located in the body?

What is the role of claudin and occludin in tight junctions?

In what type of tissues would you expect to find adherens junctions predominantly?

What distinguishes adherens junctions from desmosomes in terms of their structure?

Which type of junction is responsible for forming direct attachments between cells?

In which tissues would you expect to find HEIMDESMOSOMES predominantly?

Which type of junction is responsible for allowing small molecules and ions to pass between adjacent cells?

What is the main role of cell-matrix anchoring junctions?

Which cells are primarily responsible for producing the extracellular matrix in connective tissues?

Where are tight junctions primarily located in the body?

What is the width of the gap in GAP JUNCTIONS that allows the passage of small hydrophilic molecules?

Which type of junction anchors actin filaments in cells to the extracellular matrix?

What is the main function of INTEGRINS in cell-matrix interactions?

Which tissue type is NOT mentioned as containing GAP JUNCTIONS?

What do ACTIN-LINKED CELL-MATRIX JUNCTIONS primarily anchor in cells?

Which aspect of cell behavior can be influenced by INTEGRINS through intracellular signals?

What is the main function of desmosomes in cell junctions?

Where are zonula adherens predominantly located within tissues?

Which type of cell-cell junction is especially abundant in tissues subject to significant stretching or stress?

What is the structural difference between zonula adherens and desmosomes?

Which type of cell junction provides mechanical strength to tissues that face a lot of stress or stretching?

What is the main function of cell junctions?

Which function is NOT associated with cell junctions?

In what way do cell junctions contribute to reducing stress placed upon cells?

Which statement best describes the purpose of the paracellular barrier in epithelia?

What distinguishes adherens junctions from desmosomes?

Where are gap junctions primarily located in tissues?

What is the main function of zonula adherens junctions?

Where are desmosomes primarily located?

Which type of cell junction is structurally similar to adherens junctions but connects intermediate filaments instead of actin filaments?

What is the main function of junctional complexes?

Which type of cell junction is located more basal than tight junctions in epithelial and endothelial tissues?

What is the primary role of adhesion belts or zonula adherens?

What proteins make up tight junctions?

Where are tight junctions mostly found in the body?

What is the primary function of desmosomes in cell junctions?

Which type of tissue contains abundant anchoring junctions due to mechanical stress?

What is the main role of CADHERINS in cell-cell anchoring junctions?

Where are adherens junctions predominantly located within tissues?

What is the primary function of GAP JUNCTIONS?