Cell Growth, Division and Mitosis
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Questions and Answers

Explain why a cell's volume increasing faster than its surface area poses a challenge.

As a cell grows, the ratio of surface area to volume decreases, making it difficult for the cell to efficiently transport nutrients in and waste products out. This limitation hinders the cell's ability to sustain itself.

Describe the critical event that must occur before a cell can divide during mitosis and in which phase does it occur?

The critical event that must occur before a cell divides during mitosis is the copying of DNA, or chromosome duplication. This occurs during the S phase (synthesis phase) of the cell cycle.

During which phase of mitosis do sister chromatids separate and move toward opposite poles of the cell?

Sister chromatids separate and move toward opposite poles of the cell during anaphase.

Describe the role of the centromere during cell division.

<p>The centromere is the region where sister chromatids are attached to each other. During cell division, the centromere is the point at which the spindle fibers attach to pull the sister chromatids apart during anaphase.</p> Signup and view all the answers

How does cytokinesis differ from mitosis?

<p>Mitosis is the division of the nucleus, while cytokinesis is the division of the cytoplasm, resulting in two separate daughter cells.</p> Signup and view all the answers

Explain how cell specialization contributes to the overall function of a multicellular organism.

<p>Cell specialization allows different cells to develop unique structures and functions, which are optimized for specific tasks within the organism. This division of labor enables the organism to perform complex functions efficiently.</p> Signup and view all the answers

Describe the primary function of neurons and how their structure supports this function.

<p>Neurons are message-carrying cells that transmit electrical signals throughout the body. Their long, thin projections enable them to rapidly transmit signals over long distances.</p> Signup and view all the answers

Arrange the following terms in order from smallest to largest: organ, cell, organ system, tissue.

<p>cell, tissue, organ, organ system</p> Signup and view all the answers

What is the role of cyclin in the cell cycle, and what happens to cyclin levels during mitosis?

<p>Cyclin is a protein that regulates the timing of the cell cycle, particularly the formation of the spindle in mitosis. Cyclin levels increase to initiate mitosis, but are then used up, requiring the cell to produce more cyclin to enter mitosis a second time.</p> Signup and view all the answers

How do cancer cells differ from normal cells in terms of their response to cell cycle signals?

<p>Cancer cells do not respond to the usual signals that regulate cell growth and division. Unlike normal cells, they continue to grow and divide uncontrollably, often never exiting mitosis due to a defect in cell cycle regulation.</p> Signup and view all the answers

Flashcards

Cell Growth Limitations

Cells can only grow so large due to volume/surface area constraints; larger cells struggle with nutrient intake and waste removal.

Cell Cycle

The duration from one cell division to the next; varies between different cells, average in human adults is 20 hours.

Mitosis

The process where a cell divides into two independent daughter cells; involves duplication of DNA before division.

Interphase

The phase between cell divisions consisting of G1, S, and G2 phases where cells grow and prepare for mitosis.

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Prophase

The longest phase of mitosis where chromosomes become visible and spindle fibers start to form.

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Metaphase

The shortest phase of mitosis where chromosomes align at the cell’s center and attach to spindle fibers.

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Anaphase

The phase of mitosis where centromeres split and chromosomes move to opposite sides of the cell.

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Telophase

The phase of mitosis where two nuclei form around the separated chromosomes, and cytokinesis occurs to divide the cytoplasm.

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Cell Specialization

The process where specific cells are designed for specific functions, such as nerve or muscle cells.

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Cyclin

Proteins that regulate the timing of the cell cycle; needed for cell division and depleted after mitosis.

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Study Notes

Cell Growth and Division

  • Cell size is limited; volume increases faster than surface area, hindering nutrient intake and waste removal.
  • Large cells struggle to support their needs.
  • The cell cycle describes the time from one cell division to the next.
  • Cell division rates vary by cell type.
  • Errors in the cell cycle can be serious, like cancer.

Cell Cycle Stages

  • Interphase: The period between cell divisions, composed of:

    • G1 phase: Cell growth.
    • S phase: DNA replication (chromosome duplication).
    • G2 phase: Preparation for mitosis.
  • Mitosis (M phase): Cell division into two daughter cells.

    • Includes four key phases: prophase, metaphase, anaphase, and telophase.

Mitosis Phases

  • Prophase: Longest phase, chromosomes condense, and spindle fibers form.
    • Chromatin condenses into visible chromosomes.
    • Each chromosome consists of two identical sister chromatids joined at the centromere.
    • Centrioles move to opposite poles, forming spindle fibers.
  • Metaphase: Shortest phase, chromosomes align at the cell's equator.
  • Anaphase: Centromeres divide, sister chromatids separate and move to opposite poles.
  • Telophase: Chromosomes decondense, new nuclear membranes form around each set of chromosomes. Cytokinesis begins.

Cytokinesis

  • Cytoplasm divides, forming two separate daughter cells.

Cell Specialization

  • Specialized cells perform specific functions.
  • Four major types: nerve, epithelial, muscle, and connective.
  • Examples:
    • Macrophage: Immune cell, fights infection.
    • Neuron: Nerve cell, transmits signals.

Cellular Organization

  • Cells → Tissues → Organs → Organ Systems.
  • Organisms (both large and small) share this basic structure.

Cell Cycle Control

  • Cyclins are proteins that regulate the cell cycle by triggering certain steps.
  • Insufficient cyclin prevents DNA replication during the cell cycle.
  • Cancer cells lack normal cell cycle controls, leading to uncontrolled growth.

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Description

Explore cell growth limitations, the cell cycle stages (Interphase, Mitosis), and the phases of mitosis (prophase, metaphase, anaphase, and telophase). Understand how cells divide and the importance of each phase in creating new cells.

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