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Cell-Free DNA in Maternal Plasma

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Questions and Answers

What is the reason why maternal blood should not be taken before 10 weeks gestation?

There is too much fetally derived cfDNA in the maternal circulation before 10 weeks gestation

There is not enough fetally derived cfDNA in the maternal circulation before 10 weeks gestation (correct)

The placenta has not undergone apoptosis before 10 weeks gestation

Taking maternal blood before 10 weeks gestation can harm the fetus

What does a D positive test result in non-invasive cell free fetal DNA testing mean?

All fetuses are predicted to be D positive

The mother is RhD positive

The mother is RhD negative

At least one fetus is predicted to be D positive (correct)

What is the advantage of using non-invasive cell free fetal DNA testing to determine fetal blood group for RhD negative pregnant women?

It is less expensive than invasive testing

It offers an improved and more efficient service (correct)

It can be done earlier in gestation

It is more accurate than invasive testing

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Description

Test your knowledge about cell-free DNA in maternal plasma during pregnancy with our quiz! Learn about the role of the placenta in releasing fragmented DNA, the increasing levels of fetally derived cfDNA with gestational age, and the importance of waiting until at least 10 weeks gestation to take maternal blood samples. Keywords: pregnancy, placenta, apoptosis, cell-free DNA, maternal plasma, gestational age.