1.8: Cell Division

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Questions and Answers

A cell spends most of its time in which phase of the cell cycle?

  • M phase
  • Mitotic phase
  • Interphase (correct)
  • Cytokinesis

Which of the following represents the correct sequence of events during interphase?

  • G2, S, G1
  • S, G1, G2
  • G1, S, G2 (correct)
  • G1, G2, S

DNA replication occurs during which phase of the cell cycle?

  • S phase (correct)
  • G1 phase
  • G2 phase
  • Mitotic phase

Which of the following processes occurs during the mitotic phase?

<p>Nuclear division (B)</p> Signup and view all the answers

What is the primary function of cytokinesis?

<p>Division of the cytoplasm (C)</p> Signup and view all the answers

In which phase of the cell cycle does the cell prepare for division by synthesizing proteins and organelles?

<p>G2 phase (B)</p> Signup and view all the answers

Which of the following is NOT a function of cell division?

<p>Energy production (D)</p> Signup and view all the answers

During which phase does a cell increase in size and synthesize new proteins and organelles?

<p>G1 phase (A)</p> Signup and view all the answers

What would be the immediate consequence if cytokinesis did not occur following mitosis?

<p>The cell would have two nuclei. (B)</p> Signup and view all the answers

A researcher introduces a drug that inhibits DNA synthesis. In which phase of the cell cycle would cells likely arrest?

<p>S phase (B)</p> Signup and view all the answers

What is the primary function of the centromere in a chromosome?

<p>Attaching sister chromatids and serving as a point of attachment for spindle microtubules. (C)</p> Signup and view all the answers

During what phase of the cell cycle does chromosome duplication primarily occur?

<p>S phase (B)</p> Signup and view all the answers

What are sister chromatids?

<p>Two identical copies of a single chromosome that are connected at the centromere. (A)</p> Signup and view all the answers

Where does the assembly of spindle microtubules start?

<p>Centrosome (A)</p> Signup and view all the answers

If a cell has 46 chromosomes during G1 phase, how many sister chromatids will be present after the S phase?

<p>92 (D)</p> Signup and view all the answers

What is the relationship between a chromosome and a DNA molecule?

<p>A chromosome is a single, long DNA molecule along with associated proteins. (A)</p> Signup and view all the answers

Which of the following events directly relies on the separation of sister chromatids?

<p>Equal distribution of genetic material to daughter cells during cell division. (C)</p> Signup and view all the answers

How would disruption of the centrosome affect cell division?

<p>It would disrupt spindle microtubule formation and chromosome segregation. (B)</p> Signup and view all the answers

If a drug prevented the duplication of the centromere, what would be the most likely consequence?

<p>Failure of sister chromatids to separate correctly during cell division. (D)</p> Signup and view all the answers

Which of the following correctly describes the order of events during cell division?

<p>Chromosome duplication → spindle microtubule assembly → separation of sister chromatids (D)</p> Signup and view all the answers

In organisms exhibiting alternation of generations, such as plants and some algae, what process directly follows meiosis?

<p>Mitosis (B)</p> Signup and view all the answers

What is the ploidy of the zygote in organisms that undergo sexual reproduction?

<p>Diploid (2n) (C)</p> Signup and view all the answers

What is the primary component driving the formation of the cleavage furrow during cytokinesis in animal cells?

<p>Actin microfilaments interacting with myosin (C)</p> Signup and view all the answers

Which of the following is a key difference between meiosis in animals and meiosis in fungi?

<p>Animals produce gametes directly through meiosis, while fungi produce spores. (B)</p> Signup and view all the answers

In plant cells, what is the origin of the materials that build the new cell wall during cytokinesis?

<p>Golgi apparatus (C)</p> Signup and view all the answers

A cell with 46 chromosomes undergoes meiosis. How many chromosomes will each daughter cell have at the end of meiosis II?

<p>23 (B)</p> Signup and view all the answers

What is the main purpose of meiosis in sexually reproducing organisms?

<p>To reduce the chromosome number in gametes. (B)</p> Signup and view all the answers

Which of the following structures is characteristic of animal cell cytokinesis but not plant cell cytokinesis?

<p>Cleavage furrow (B)</p> Signup and view all the answers

What is the relationship between the metaphase plate and the location of the cleavage furrow in animal cell cytokinesis?

<p>The cleavage furrow forms near where the old metaphase plate was located. (C)</p> Signup and view all the answers

Which process contributes to genetic variation in sexually reproducing organisms?

<p>Meiosis during gamete formation (C)</p> Signup and view all the answers

How do sister chromatids and homologous chromosomes differ during meiosis?

<p>Sister chromatids are identical copies of each other, while homologous chromosomes are similar but not identical and carry the same genes but may have different alleles. (D)</p> Signup and view all the answers

Which of the following best describes the phragmoplast's role in plant cell cytokinesis?

<p>It directs the formation of the cell plate from Golgi-derived vesicles. (C)</p> Signup and view all the answers

What would be the most likely outcome if myosin were inhibited during animal cell cytokinesis?

<p>The cell would be unable to form a cleavage furrow and divide. (C)</p> Signup and view all the answers

In the context of sexual life cycles, what is the role of fertilization?

<p>To produce diploid cells from haploid gametes. (A)</p> Signup and view all the answers

A karyotype reveals that a human cell has 47 chromosomes. Which of the following most likely occurred?

<p>A gamete with an extra chromosome was fertilized. (D)</p> Signup and view all the answers

How does cytokinesis differ fundamentally between animal and plant cells?

<p>Animal cells divide by pinching the cell membrane; plant cells build a new cell wall. (C)</p> Signup and view all the answers

A researcher introduces a drug into plant cells that prevents the Golgi apparatus from producing vesicles. What is the most likely consequence?

<p>The cells would be unable to complete cytokinesis. (B)</p> Signup and view all the answers

If a plant species has a diploid number of 12 ($2n = 12$), what is the haploid number ($n$) in its gametes?

<p>6 (C)</p> Signup and view all the answers

If a cell lacked centrioles, what aspect of cell division would be most directly affected?

<p>Organization of the microtubule-organizing center in animal cells. (C)</p> Signup and view all the answers

During plant cell cytokinesis, what initiates the formation of the cell plate?

<p>Initiation by spindle microtubules to form the phragmoplast. (D)</p> Signup and view all the answers

Flashcards

Cell Cycle

The repeating series of growth, DNA replication, and division.

Interphase

The stage involving cell growth and preparation for division.

G1 Phase

The first growth phase of interphase.

S Phase

The phase of interphase where DNA is replicated.

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G2 Phase

The second growth phase of interphase, preparing for mitosis.

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Mitosis

The phase involving nuclear division.

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Cytokinesis

The phase involving division of the cytoplasm.

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Cell Division Functions

Cell division results in reproduction, growth, and repair.

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Mitotic (M) Phase

The phase of the cell cycle that includes mitosis and cytokinesis.

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Interphase Duration

Longest part of the cell cycle, where the cell grows and prepares for division.

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Chromosome

A cellular structure carrying hereditary information.

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DNA molecules

A complex of DNA and proteins that makes up chromosomes.

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Sister Chromatids

One of the two identical copies of a chromosome formed after DNA replication.

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Centromere

The region of a chromosome where the two sister chromatids attach.

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Chromosome Arm Duplication

The duplication of a chromosome, resulting in two identical copies.

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Centromere

The point of attachment for sister chromatids on a chromosome.

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Separation of Sister Chromatids

The process where sister chromatids are pulled apart.

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Centrosome

An organelle near the nucleus of a cell that contains the centrioles (in animal cells) and from which the spindle fibers develop in cell division.

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Spindle Microtubules

Fibers that form the mitotic spindle and help separate sister chromatids during cell division.

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Microtubule Assembly

Assembly of the spindle microtubules starts here.

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Diploid

Cells with two sets of chromosomes (2n).

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Haploid

Cells with one set of chromosomes (n).

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Fertilization

The union of haploid gametes to produce a diploid zygote.

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Karyotype

A display of homologous chromosomes arranged in order of size.

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Gamete

A reproductive cell containing only one set of chromosomes (n).

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Diploid Zygote

Having two sets of chromosomes, one from each parent.

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Spores

Reproductive cells produced by plants and some algea.

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Homologous Chromosomes

Pair of chromosomes with same length, centromere position, and staining pattern that possess genes for the same characters at corresponding loci.

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Centrioles

Organelles located within the centrosome, whose function is somewhat undefined

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Cleavage Furrow

The first visible sign of cytokinesis in animal cells.

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Contractile Ring

Ring responsible for the cleavage furrow.

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Cell Plate

A structure formed during telophase in plant cells for cytokinesis.

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Phragmoplast

Vesicles from the Golgi that merge to form the cell plate during cytokinesis in plant cells.

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Telophase

Stage of mitosis when the nuclear envelope reforms and chromosomes decondense.

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Actin microfilaments

Associated with myosin during the cleavage furrow.

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Coalesce

A structure in plant cells where vesicles from the Golgi apparatus coalesce during telophase and cytokinesis.

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Study Notes

  • Cell division functions in reproduction, growth, and repair/tissue renewal

Cell Cycle Overview

  • Cell cycle stages are interphase and mitotic phase
  • Mitotic (M) phase alternates with the much longer interphase
  • Interphase accounts for about 90% of the cell cycle

Interphase Details

  • Interphase consists of G1 phase, S phase, and G2 phase
  • G1 phase involves cell growth
  • S phase involves growth and DNA synthesis
  • G2 phase involves growth and preparation for cell division

Mitotic Phase Details

  • Mitotic phase includes mitosis and cytokinesis
  • Mitosis is nuclear division
  • Cytokinesis is division of the cytoplasm

Chromosomes

  • Chromosomes are made of DNA molecules
  • Chromosome duplication includes DNA synthesis
  • Sister chromatids form after duplication
  • Sister chromatids separate during cell division at the centromere

Mitosis Stages

  • Mitosis includes prophase, prometaphase, metaphase, anaphase, telophase
  • During prophase, chromatin condenses, nucleoli disappear, and the mitotic spindle forms
  • The centrosomes move away from each other, propelled by microtubules
  • In prometaphase, the nuclear envelope fragments
  • Microtubules extend into nuclear area and attach to kinetochores
  • Metaphase involves the chromosomes aligning at the metaphase plate
  • In anaphase, sister chromatids separate and move to opposite ends of the cell
  • Telophase involves the formation of two daughter nuclei
  • Nuclear envelopes reform, chromosomes decondense

Spindle Microtubules

  • Assembly of the spindle microtubules starts in the centrosome
  • The centrosome is the microtubule-organizing center
  • Animal cells have a pair of centrioles at the center of the centrosome
  • The function of centrioles is somewhat undefined

Cytokinesis

  • Cytokinesis, division of the cytoplasm typically follows mitosis
  • In animal cells, the first sign of cytokinesis (cleavage) is the appearance of a cleavage furrow
  • The cleavage furrow is a contractile ring of actin microfilaments associated with myosin
  • The ring contracts and deepens to divide the cell
  • In plant cells, during telophase, vesicles from the Golgi coalesce (phragmoplast) at the metaphase plate, forming a cell plate
  • The cell plate grows until it fuses with plasma membrane

Meiosis and Sexual Life Cycles

  • Meiosis is a type of cell division that reduces the number of sets of chromosomes from two to one
  • Fertilization is union of gametes
  • Results in offspring with the same number of chromosomes as their parents

Karyotype

  • Karyotype is the number and appearance of chromosomes in the nucleus of a eukaryotic cell
  • Pair of homologous replicated chromosomes with centromere and sister chromatids
  • Metaphase chromosome with sister chromatids

Chromosome Sets

  • 2n = 6 means maternal set of chromosomes (n = 3) and paternal set of chromosomes (n = 3)
  • Two sister chromatids of one replicated chromosome connected at the centromere
  • Pair of homologous chromosomes (one from each set)

Meiosis I and II

  • Interphase I of meiosis features a homologous pair of chromosomes in a diploid parent cell (2n)
  • Chromosomes replicate forming homologous pair of replicated chromosomes with sister chromatids
  • Meiosis I involves the separation of homologous chromosomes resulting in haploid cells with replicated chromosomes
  • Meiosis II involves the separation of sister chromatids, resulting in haploid cells with unreplicated chromosomes

Meiosis I Details

  • During prophase I, homologous chromosomes pair and crossing over occurs
  • In metaphase I, homologous pairs line up at the metaphase plate
  • In anaphase I, homologous chromosomes separate
  • In telophase I, two haploid cells form, each with duplicated chromosomes

Meiosis II Details

  • During prophase II, a spindle apparatus forms
  • In metaphase II, sister chromatids align at the metaphase plate
  • In anaphase II, sister chromatids separate

MITOSIS vs MEIOSIS

  • During mitosis Parent cell chromosome replication, chromosomes align at the metaphase plate, sister chromatids separate during anaphase
  • Results in two identical daughter cells
  • During meiosis Parent cell chromosome replication, tetrads align at the metaphase plate during Meiosis I
  • Homologous chromosomes separate during anaphase I and sister chromatids separate during anaphase II
  • Results in four genetically distinct daughter cells

Microsporogenesis

  • Microsporogenesis is formation of spores called microspores
  • Development of microspore into the microgametophyte or the pollen tube
  • Includes meiotic and mitotic division in the development of pollen

Megagametogenesis

  • Megasporogenesis refers to the development of a female gametophyte or embryo sac

Mitosis vs Meiosis - Summary

Feature Mitosis Meiosis
DNA replication Occurs during interphase before nuclear division begins Occurs once, during the interphase before meiosis I begins
Number of divisions One, including prophase, metaphase, anaphase, and telophase Two, each including prophase, metaphase, anaphase, and telophase
Synapsis of homologous chromosomes Does not occur Synapsis is unique to meiosis, involves homologous chromosomes joining along their length forming tetrads; associated with crossing over between nonsister chromatids
Number of daughter cells and genetic composition Two diploid (2n) are genetically identical to the parent cell Four haploid (n), each with chromosome half as parent has; Genetic non identical to parent cells
Role Enables multicellular adult to arise from zygote; produces cells for growth and tissue repair Produces gametes; reduces chromosome number by half and introduces genetic variability among the gametes

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