30 Questions
During which phase of the cell cycle does the c number double?
S phase
Which phase of meiosis is responsible for generating haploid gametes?
Meiosis I
During which phase of meiosis does crossing-over or homologous recombination occur?
Prophase I
What is the ploidy number throughout the cell cycle?
2n
How many copies of DNA double helices are there in each chromosome during G2 phase?
4
Which phase of meiosis is responsible for pulling apart sister chromatids into daughter cells?
Anaphase II
How many possible combinations of chromosomes can be generated through independent assortment?
8.4 million
What is the average number of times crossing-over or homologous recombination occurs in humans?
2
What is the percentage of variation in human genomic sequences?
0.1%
What is the term for different versions of a gene?
Alleles
During which phase of the cell cycle does DNA and chromosomes replicate?
S
What are the functions of the cell cycle and cell division?
Both of the above
What is the main difference between spermatogenesis and oogenesis?
Spermatogenesis occurs in males, while oogenesis occurs in females.
What is the purpose of mitosis and cytokinesis?
To divide the cell and segregate chromosomes into daughter cells
How does genetic diversity generate during sexual reproduction?
Through the combination of genetic material from two parents
What is the relationship between race and genetics?
Race is a social construct that does not directly correspond to genetic differences
What changes through the cell cycle and meiosis?
Both chromosome content (n) and DNA content (c)
What are DNA sequence variants?
Differences in DNA sequence between individuals
Where is the distribution of human genetic diversity highest?
Africa
What happens during the G1 phase of the cell cycle?
Growth and metabolism
Which term refers to the most common allele of a gene in a population?
Wild-type allele
What is the definition of a mutation?
A DNA sequence variant arising due to DNA replication errors or other DNA damage
What is the definition of polymorphisms?
A variant found in less than 1% of the population
What is the definition of a variant?
Any alteration in DNA sequence from the wild-type
What is the Out of Africa Hypothesis?
All of the above
How many waves of migration are associated with the Out of Africa Hypothesis?
2
When did the first wave of migration associated with the Out of Africa Hypothesis occur?
130,000-115,000 years ago
Where did the second wave of migration associated with the Out of Africa Hypothesis potentially establish?
China
What percentage of the population is associated with the second wave of migration?
1%
What is the definition of a rare variant?
A variant found in less than 1% of the population
Test your knowledge on cell division and human genetic diversity with this quiz by Dr. David Rodda, PhD. Learn about the segregation of chromosomes in mitosis and meiosis, changes in chromosome and DNA content, differences between spermatogenesis and oogenesis, and more. Challenge yourself and expand your understanding of this fascinating topic.
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