Podcast
Questions and Answers
Which process leads to the tumour outgrowing its blood supply?
Which process leads to the tumour outgrowing its blood supply?
- Apoptosis resistance
- Immune evasion
- Altered metabolism
- Sustained angiogenesis (correct)
What is the hypothesis called where one genetic change is inherited, and the second mutation occurs in a retinal cell?
What is the hypothesis called where one genetic change is inherited, and the second mutation occurs in a retinal cell?
- Wahlberg effect
- Knudson's Two Hit Hypothesis (correct)
- Li-Fraumeni hypothesis
- APC/Beta-catenin pathway
In viral carcinogenesis, what does insensitivity to growth inhibition lead to?
In viral carcinogenesis, what does insensitivity to growth inhibition lead to?
- Apoptosis evasion (correct)
- Tumour growth promotion
- Immune system activation
- Altered metabolism
Which protein enables DNA damage repair and is rendered ineffective by a BRCA mutation?
Which protein enables DNA damage repair and is rendered ineffective by a BRCA mutation?
What is the most common cancer associated with Li-Fraumeni syndrome?
What is the most common cancer associated with Li-Fraumeni syndrome?
What neoplasm is associated with APC/Beta-catenin gene mutation?
What neoplasm is associated with APC/Beta-catenin gene mutation?
Which tumour suppressor gene is widely disregulated in cancer?
Which tumour suppressor gene is widely disregulated in cancer?
What causes a mutant cell to arise due to DNA remaining damaged?
What causes a mutant cell to arise due to DNA remaining damaged?
What is the main function of Nivolumab in immunotherapy for head and neck cancer?
What is the main function of Nivolumab in immunotherapy for head and neck cancer?
Which process is responsible for making cancer cells evade detection by cytotoxic T cells?
Which process is responsible for making cancer cells evade detection by cytotoxic T cells?
