Cell Cycle Phases

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What is the percentage of time spent in mitosis phase for mammalian cells?

3-5%

What is the function of the G1 phase in the cell cycle?

Cells prepare for DNA replication and growth

What is the main function of kinetochore microtubules?

Attaching to the centromere of the chromosomes

What is the function of astral microtubules during mitosis?

Reaching out to the negative center and binding to membrane proteins

What is the main difference between G0 and G1 phases?

G0 is a quiescent state, while G1 prepares for DNA replication

What is the function of the synthesis phase in the cell cycle?

DNA synthesis occurs, resulting in the replication of the genome

What happens during the G1 phase of the cell cycle?

Cells prepare for DNA replication and growth

What is the main function of microtubules during mitosis?

To facilitate the alignment and segregation of chromosomes

Which type of microtubules interacts with microtubules from the opposite pole of the cell?

Polar microtubules

What is the role of crosslink proteins during mitosis?

To facilitate the alignment and segregation of chromosomes

What is the primary function of the G2 phase?

To prepare cells for mitosis

What is the relationship between the plus end and minus end of microtubules during mitosis?

The plus end is attached to the spindle pole, and the minus end is attached to the kinetochore

What is the purpose of the Mitotic Index?

To measure the percentage of time spent in mitosis phase

What is the primary function of kinetochores during mitosis?

To attach to the centromere of the chromosomes

What is the purpose of the quiescent state in the G0 phase?

To allow cells to enter a state of dormancy

Understand the different stages of the cell cycle, including mitosis, G0, G1, S, and G2 phases. Learn about the processes that occur during each phase, such as DNA replication and cell growth.

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