Cell Cycle & Genetics

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Questions and Answers

Cytogenetic analysis reveals a pericentric inversion and a paracentric inversion in a chromosome. What can cytogeneticists determine based on this information?

  • The location and type of inversions. (correct)
  • The specific proteins affected by the inversions.
  • The rate of transcription of genes near the inversion breakpoints.
  • The exact gene sequence within the inverted regions.

A researcher observes a cell undergoing DNA replication. In which phase of the cell cycle is this cell?

  • Telophase
  • S phase (correct)
  • Prophase
  • G1 phase

A student is creating a model of the cell cycle but mixes up the order of the stages. Which of the following sequences accurately represents the cell cycle?

  • Prophase, interphase, metaphase, anaphase, telophase.
  • Telophase, metaphase, anaphase, prophase, interphase.
  • Prophase, anaphase, telophase, interphase, metaphase.
  • Interphase, prophase, metaphase, anaphase, telophase. (correct)

A geneticist is analyzing a human karyotype and notices an abnormality. Which of the following observations would indicate a normal human karyotype?

<p>karyotype displays 46 different chromosomes (A)</p> Signup and view all the answers

Comparing homologous chromosomes, which statement is true?

<p>Homologous chromosomes are referred to in karyograms using the same number (C)</p> Signup and view all the answers

In comparing mitotic to meiotic anaphase, which of the following is true?

<p>Anaphase in mitotic cells is quite similar to Anaphase II in meiotic cells. (B)</p> Signup and view all the answers

A researcher is studying a cell undergoing division and observes that sister chromatids are being pulled apart towards opposite poles. Which stage of cell division is the researcher observing?

<p>Anaphase (D)</p> Signup and view all the answers

A student observes a cellular process where the nuclear envelope is re-forming around separated sets of chromosomes. Which stage of the cell cycle is the student observing?

<p>Telophase (B)</p> Signup and view all the answers

A researcher is examining cells under a microscope and notices that the nuclear envelope is breaking down in several cells. Which stage of cell division are these cells likely entering?

<p>Metaphase (D)</p> Signup and view all the answers

A researcher is observing cells and notes that chromosomes are becoming more tightly coiled and condensed. Which stage of mitosis is characterized by chromosome condensation?

<p>Prophase (C)</p> Signup and view all the answers

Flashcards

Anaphase

The stage of the cell cycle when sister chromatids separate.

Telophase

The stage of the cell cycle when the nuclear envelope reassembles.

Pseudoautosomal genes

Genes present on both sex chromosomes.

Sex determination in fruit flies

The ratio of X chromosomes to autosomes

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Polyploidy

The presence of extra chromosome sets (more than diploid)

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Metacentric chromosome

A chromosome with a centrally located centromere and equally sized arms.

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Pericentric inversions

Change the relative lengths of the chromosomal arms

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Formation of allopolyploids

A hybridization event between two different species

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Hemizygous

Possessing only one copy of a gene in a diploid organism.

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Study Notes

  • Cytogeneticists use pericentric and paracentric inversions to determine the timing of certain events
  • Sister chromatids form during the S phase of the cell cycle
  • The appropriate order of the cell cycle is interphase, prophase, metaphase, anaphase, telophase (IPMAT)
  • A normal human karyotype contains 23 pairs of homologues, 46 different chromosomes, 22 pairs of autosomes, and 2 sex chromosomes
  • Homologous chromosomes do not represent identical DNA strands.
  • Anaphase in mitotic cells is similar to anaphase II in meiotic cells
  • Sister chromatids separate during anaphase
  • The nuclear envelope assembles during telophase
  • Metaphase happens right after the nuclear envelope breaks down
  • Chromosome condensation occurs during prophase
  • Chromosome decondensation occurs during telophase
  • Interphase is the longest stage.
  • Crossing a dwarf pea plant with a true-breeding tall plant yields 0% dwarf pea plants in the F1 generation
  • From the previous cross, there is one genotype produced
  • In a self-cross of yellow, round, tall hybrid plants (Gg Ww DD), approximately 3/16 of the progeny will be yellow, wrinkled, and tall
  • Codominant alleles are represented by symbols with superscripts
  • Variable phenotypes in flies with the Lobe eye mutation is the best example of expressivity
  • AB blood type from an A and B cross is the best example for codominance
  • A cross between AB and O parents can result in a maximum of 2 blood types
  • An organism with only one copy of a gene called hemizygous
  • A female and normal individual results when an XX individual has two copies of the mutant testicular feminization gene
  • Pseudoautosomal genes are present on both sex chromosomes.
  • In fruit flies, sex determination is based on the ratio of X chromosomes to autosomes
  • An "XY" human lacking the SRY region will be female
  • The maximum number of Barr bodies in each cell of an XXXY human is 2
  • The letter "p" denotes the short arm of a chromosome. The long arm is denoted by the letter “q”
  • The presence of extra chromosome sets is common in plants, which makes polyploid organisms
  • A hybridization event between two different species most likely results in the formation of allopolyploids
  • Turner syndrome is an example of a hypoploid organism
  • A metacentric chromosome contains a centrally located centromere and equally sized arms
  • Pericentric inversions change the relative lengths of the chromosomal arms
  • Two genes located on the same chromosome will not always appear to be linked after the appropriate cross is examined

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