Podcast
Questions and Answers
What is the first visible change of cytokinesis in an animal cell?
What is the first visible change of cytokinesis in an animal cell?
- Division of the cell in two
- Assembly of actin filaments
- Formation of a contractile ring
- Appearance of a cleavage furrow (correct)
Which structure is responsible for the division of an animal cell during cytokinesis?
Which structure is responsible for the division of an animal cell during cytokinesis?
- Myosin II filaments
- Contractile ring (correct)
- Actin filaments
- RhoA protein
What triggers the assembly and contraction of the contractile ring during cytokinesis?
What triggers the assembly and contraction of the contractile ring during cytokinesis?
- Activation of RhoA by RhoGEF (correct)
- Division of the cell in two
- Assembly of actin filaments
- Release of GDP by Myosin II
What is the function of RhoA in cytokinesis?
What is the function of RhoA in cytokinesis?
Which protein is involved in the formation of the contractile ring in animal cells?
Which protein is involved in the formation of the contractile ring in animal cells?
What is the role of a guanine nucleotide exchange factor (RhoGEF) during cytokinesis?
What is the role of a guanine nucleotide exchange factor (RhoGEF) during cytokinesis?
Which process occurs just beneath the plasma membrane during anaphase?
Which process occurs just beneath the plasma membrane during anaphase?
What is the main structure underlying cytokinesis in an animal cell?
What is the main structure underlying cytokinesis in an animal cell?
Where does the contractile ring assemble during cytokinesis?
Where does the contractile ring assemble during cytokinesis?
What is the function of RhoA during cytokinesis?
What is the function of RhoA during cytokinesis?
Which protein is essential for the contraction of the contractile ring during animal cell cytokinesis?
Which protein is essential for the contraction of the contractile ring during animal cell cytokinesis?
What triggers the formation of the cleavage furrow during cytokinesis in animal cells?
What triggers the formation of the cleavage furrow during cytokinesis in animal cells?
Which factor stimulates the release of GDP and binding of GTP to RhoA during cytokinesis?
Which factor stimulates the release of GDP and binding of GTP to RhoA during cytokinesis?
What is the role of actin filaments in the contractile ring during cytokinesis?
What is the role of actin filaments in the contractile ring during cytokinesis?
During which cell cycle phase does the contractile ring assemble in preparation for cell division?
During which cell cycle phase does the contractile ring assemble in preparation for cell division?
What is the role of cyclins in the activity of Cdks?
What is the role of cyclins in the activity of Cdks?
Which class of cyclins helps govern the activities of G1/S-cyclins in late G1?
Which class of cyclins helps govern the activities of G1/S-cyclins in late G1?
When do M-cyclin levels decrease?
When do M-cyclin levels decrease?
Which type of cyclin stimulates entry into mitosis at the G2/M transition?
Which type of cyclin stimulates entry into mitosis at the G2/M transition?
What happens to S-cyclin levels until mitosis begins?
What happens to S-cyclin levels until mitosis begins?
What is the role of securin destruction at the end of metaphase?
What is the role of securin destruction at the end of metaphase?
What is the consequence of APC/C targeting S- and Mcyclins for destruction?
What is the consequence of APC/C targeting S- and Mcyclins for destruction?
How does APC/C activation occur?
How does APC/C activation occur?
What is the significance of M-Cdk promoting Cdc20–APC/C activity?
What is the significance of M-Cdk promoting Cdc20–APC/C activity?
What occurs when Cdk becomes inactivated in the cell cycle?
What occurs when Cdk becomes inactivated in the cell cycle?
What is the role of the Anaphase-Promoting Complex/Cyclosome (APC/C) in late M phase events?
What is the role of the Anaphase-Promoting Complex/Cyclosome (APC/C) in late M phase events?
What is the function of Cdk-activating kinase (CAK) during M-Cdk activation?
What is the function of Cdk-activating kinase (CAK) during M-Cdk activation?
What triggers the activation of the 'stockpile' of M-Cdk at the end of G2 phase?
What triggers the activation of the 'stockpile' of M-Cdk at the end of G2 phase?
What is the role of protein phosphatase Cdc25 in M-Cdk activation?
What is the role of protein phosphatase Cdc25 in M-Cdk activation?
How does positive feedback loops contribute to M-Cdk activation during mitosis?
How does positive feedback loops contribute to M-Cdk activation during mitosis?
What is the role of cyclin in the activation of Cdk?
What is the role of cyclin in the activation of Cdk?
Which type of phosphorylation inhibits the activity of a cyclin–Cdk complex?
Which type of phosphorylation inhibits the activity of a cyclin–Cdk complex?
What structural change occurs in the Cdk protein upon binding with cyclin?
What structural change occurs in the Cdk protein upon binding with cyclin?
Which protein phosphorylates an amino acid near the entrance of the Cdk active site for full activation of the cyclin–Cdk complex?
Which protein phosphorylates an amino acid near the entrance of the Cdk active site for full activation of the cyclin–Cdk complex?
What effect does dephosphorylation by Cdc25 have on a cyclin–Cdk complex?
What effect does dephosphorylation by Cdc25 have on a cyclin–Cdk complex?
