Cell Cycle and Mitosis
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Questions and Answers

During which phase of the cell cycle is DNA replicated?

  • G1 phase
  • M phase
  • S phase (correct)
  • G2 phase
  • In which phase of the cell cycle do some cells remain nonproliferative but viable and functional?

  • G1 phase
  • M phase
  • S phase
  • Go phase (correct)
  • Which phase of the cell cycle is known for active RNA and protein synthesis?

  • G2 phase
  • G1 phase (correct)
  • M phase
  • Go phase
  • Which phase of the cell cycle has the highest variability in duration, leading to the overall variability of cell cycle times?

    <p>G1 phase</p> Signup and view all the answers

    In which phase of the cell cycle are chromosomes duplicated to become tetraploid?

    <p>S phase</p> Signup and view all the answers

    Which family of proteins governs the transition of a cell from one phase to another in the cell cycle?

    <p>Cyclins</p> Signup and view all the answers

    What initiates the cell cycle?

    <p>Growth factor receptor</p> Signup and view all the answers

    Which complex catalyzes the phosphorylation of the retinoblastoma (Rb) protein?

    <p>Cyclin D-CDK4/CDK6</p> Signup and view all the answers

    Which complex forms in late G1 and is necessary for the progression from G1 to S phase in the cell cycle?

    <p>Cyclin E &amp; CDK2</p> Signup and view all the answers

    What becomes active once separated from the dephosphorylated Rb protein in the cell cycle?

    <p>E2F</p> Signup and view all the answers

    What is the duration of the G1 phase in the cell cycle?

    <p>6-12 hours</p> Signup and view all the answers

    Which phase of the cell cycle is characterized by the active synthesis of RNA and proteins?

    <p>G1 phase</p> Signup and view all the answers

    What represents the time spent by a cell prior to preparation for active division?

    <p>Resting phase (Go)</p> Signup and view all the answers

    In which phase of the cell cycle are chromosomes duplicated to become tetraploid?

    <p>S phase</p> Signup and view all the answers

    What is the main reason for the high variability of cell cycle times?

    <p>Variability of G1 phase</p> Signup and view all the answers

    What is the primary role of cyclin D in the cell cycle?

    <p>Forming a complex with CDK4 and CDK6 to activate E2F</p> Signup and view all the answers

    What is the function of cyclin E in the late G1 phase of the cell cycle?

    <p>Rapidly degrading to release CDK2</p> Signup and view all the answers

    Which proteins govern the transition of a cell from one phase to another in the cell cycle?

    <p>Cyclins</p> Signup and view all the answers

    What does the binding of a growth factor to the growth factor receptor on the plasma membrane initiate in the cell cycle?

    <p>Production of cyclins</p> Signup and view all the answers

    What is the role of the retinoblastoma (Rb) protein in the cell cycle?

    <p>Separating from E2F to become active</p> Signup and view all the answers

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