Cell Cycle and DNA Structure

If a cell's DNA polymerase suddenly lost its proofreading ability, which of the following would be the most likely and direct consequence?

A researcher is studying a cell line and observes that the cells are entering S phase much more rapidly than expected. Which alteration would best explain this observation?

During DNA replication, the leading strand is synthesized continuously while the lagging strand is synthesized in fragments. What is the primary reason for this difference?

Imagine a cell where the function of DNA ligase is completely inhibited. Which of the following would you expect to observe?

If a cell were unable to produce histone proteins, which of the following would be a likely consequence?

A mutation occurs in a cell such that it cannot produce single-strand binding proteins. What is the most likely result of this mutation during DNA replication?

If a researcher discovers a new form of DNA polymerase that can synthesize DNA in both the 5' to 3' and 3' to 5' direction, what would be the most significant implication for DNA replication?

During which phase of the cell cycle are chromosomes typically least condensed?

What would be the most likely effect of a drug that prevents the shortening of spindle fibers during anaphase?

A cell with a high mutation rate is found to have a non-functional RNA primase. How does the loss of this enzyme lead to an increased mutation rate?

If a cell is treated with a drug that inhibits the function of helicase, which process would be most directly affected?

What is the significance of bidirectional replication in DNA synthesis?

How would inhibiting topoisomerase activity most directly impact DNA replication?

If a cell lacked the ability to perform cytokinesis, what would be the most likely result?

What is the primary purpose of the sugar and phosphate backbone in a DNA molecule?

Considering the antiparallel nature of DNA, if one strand has the sequence 5'-ATGC-3', what would be the sequence of the complementary strand?

What is the most likely consequence of a mutation that causes the overproduction of cyclin-dependent kinases (CDKs)?

What is the immediate consequence if a cell fails to pass the spindle assembly checkpoint during mitosis?

During which phase of mitosis does the nuclear envelope reform around the separated sister chromatids?

What is the primary function of the centromere during mitosis?

How does the semi-conservative nature of DNA replication contribute to genetic stability?

Why is it essential for chromosomes to condense during prophase of mitosis?

If a cell has 46 chromosomes during G1 phase, how many sister chromatids will it have during prophase after S phase?

What characteristic of DNA allows it to be accurately copied during replication?

Why is DNA replication described as 'semi-conservative'?

Which enzyme is primarily responsible for adding nucleotides to the growing DNA strand during replication?

During which phase of the cell cycle does DNA replication occur?

What is the role of RNA primase in DNA replication?

Which even occurs during anaphase?

Which of the following is the correct order of the phases of mitosis?

During which phase of mitosis are chromosomes completely aligned at the metaphase plate?

A new drug is discovered that disrupts the hydrogen bonds between DNA base pairs. Which cellular process would be most immediately affected?

In the G1 phase of the cell cycle, what primary activity is occurring?

What is the role of cytokinesis in the cell cycle?

Which feature describes the antiparallel nature of DNA?

What is the key distinction between leading and lagging strands during DNA replication?

If a researcher introduces a non-hydrolyzable analog of ATP into a cell, thereby inhibiting all ATP-dependent reactions, what phase of the cell cycle would be most immediately affected?

Which event primarily characterizes the S phase of the cell cycle?

What is the main function of DNA ligase in DNA replication?