Cell Cycle and Cell Division Quiz

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Questions and Answers

During which phase of the cell cycle is DNA replicated?

  • G2
  • G0
  • S (correct)
  • G1

Where does the 'restriction point' occur in the cell cycle?

  • G1 (correct)
  • M
  • G0
  • G2

In which phase are nerve and muscle cells typically found?

  • G1
  • G2
  • G0 (correct)
  • S

When is the cyclin component of MPF destroyed in the cell cycle?

<p>M (C)</p> Signup and view all the answers

Which phase of the cell cycle is known as the 'Gap 2' phase?

<p>G2 (A)</p> Signup and view all the answers

What characteristic is commonly observed in cells from an advanced malignant tumor?

<p>Abnormal chromosomes (D)</p> Signup and view all the answers

Why might cancer cells from an advanced malignant tumor have abnormal chromosomes?

<p>Introduction of new chromosomes through transformation (C)</p> Signup and view all the answers

What is a possible consequence of cancer cells no longer being density dependent?

<p>Increased metastasis (C)</p> Signup and view all the answers

Besides overproliferation, what could lead to the formation of a tumor?

<p>Failure to undergo appropriate cell death (B)</p> Signup and view all the answers

What process might contribute to the abnormal chromosome numbers seen in advanced malignant tumors?

<p>Bypassing cell cycle checkpoints (A)</p> Signup and view all the answers

What could logically result in the inability of chromosomes to properly align at the metaphase plate?

<p>Failure to form functional spindles (C)</p> Signup and view all the answers

What did the research team conclude based on the incorporation of labeled nucleotides into a culture of lymphocytes?

<p>Infection causes lymphocytes to divide more rapidly. (D)</p> Signup and view all the answers

What is the outcome if mammalian cells receive a go-ahead signal at the G1 checkpoint?

<p>Complete the cycle and divide. (A)</p> Signup and view all the answers

What happens to cells that are in a nondividing state?

<p>Switch to a nondividing state. (B)</p> Signup and view all the answers

How does the presence of a pathogen affect the labeled nucleotide incorporation in lymphocytes?

<p>Increases nucleotide incorporation in lymphocytes. (D)</p> Signup and view all the answers

What is the significance of the G1 checkpoint in mammalian cells?

<p>Triggers cell division. (C)</p> Signup and view all the answers

How do infections affect cell cultures according to the text?

<p>Stimulate lymphocytes to divide rapidly. (C)</p> Signup and view all the answers

What is the protein that is synthesized at specific times during the cell cycle and associates with a kinase to form a catalytically active complex?

<p>MPF (D)</p> Signup and view all the answers

Which protein, maintained at constant levels throughout the cell cycle, requires cyclin to become catalytically active?

<p>cyclin (D)</p> Signup and view all the answers

What triggers the cell's passage past the G2 checkpoint into mitosis?

<p>MPF (D)</p> Signup and view all the answers

Which one of the following is NOT a correct match between the protein and its role in the cell cycle?

<p>Cdk - Inhibits cell division (B)</p> Signup and view all the answers

During which phase of the cell cycle is cyclin maintained at constant levels?

<p>G1 phase (A)</p> Signup and view all the answers

What is the main function of spindle microtubules that do not attach to kinetochores?

<p>Maintaining the area where fibers overlap in the cell's center (D)</p> Signup and view all the answers

How can radiolabeled nucleotides be used to track their incorporation into newly forming DNA?

<p>To identify the exact location where DNA synthesis initiates (D)</p> Signup and view all the answers

What is the primary purpose of introducing labeled T nucleotides into a culture of dividing human cells at specific times?

<p>To monitor the incorporation of nucleotides into newly forming DNA (C)</p> Signup and view all the answers

Which aspect of cellular activity is NOT directly related to spindle microtubules during mitosis?

<p>Initiation of DNA replication (B)</p> Signup and view all the answers

Why is it significant to introduce labeled T nucleotides into a culture of dividing human cells when studying DNA synthesis?

<p>To track and analyze how nucleotides are integrated into replicating DNA (C)</p> Signup and view all the answers

In the context of monitoring DNA replication, what information can be obtained by tracking the incorporation of radiolabeled nucleotides?

<p>The timing and duration of specific phases in the cell cycle (C)</p> Signup and view all the answers

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