Cell Cycle and Cell Division Quiz
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Questions and Answers

During which phase of the cell cycle is DNA replicated?

  • G2
  • G0
  • S (correct)
  • G1
  • Where does the 'restriction point' occur in the cell cycle?

  • G1 (correct)
  • M
  • G0
  • G2
  • In which phase are nerve and muscle cells typically found?

  • G1
  • G2
  • G0 (correct)
  • S
  • When is the cyclin component of MPF destroyed in the cell cycle?

    <p>M</p> Signup and view all the answers

    Which phase of the cell cycle is known as the 'Gap 2' phase?

    <p>G2</p> Signup and view all the answers

    What characteristic is commonly observed in cells from an advanced malignant tumor?

    <p>Abnormal chromosomes</p> Signup and view all the answers

    Why might cancer cells from an advanced malignant tumor have abnormal chromosomes?

    <p>Introduction of new chromosomes through transformation</p> Signup and view all the answers

    What is a possible consequence of cancer cells no longer being density dependent?

    <p>Increased metastasis</p> Signup and view all the answers

    Besides overproliferation, what could lead to the formation of a tumor?

    <p>Failure to undergo appropriate cell death</p> Signup and view all the answers

    What process might contribute to the abnormal chromosome numbers seen in advanced malignant tumors?

    <p>Bypassing cell cycle checkpoints</p> Signup and view all the answers

    What could logically result in the inability of chromosomes to properly align at the metaphase plate?

    <p>Failure to form functional spindles</p> Signup and view all the answers

    What did the research team conclude based on the incorporation of labeled nucleotides into a culture of lymphocytes?

    <p>Infection causes lymphocytes to divide more rapidly.</p> Signup and view all the answers

    What is the outcome if mammalian cells receive a go-ahead signal at the G1 checkpoint?

    <p>Complete the cycle and divide.</p> Signup and view all the answers

    What happens to cells that are in a nondividing state?

    <p>Switch to a nondividing state.</p> Signup and view all the answers

    How does the presence of a pathogen affect the labeled nucleotide incorporation in lymphocytes?

    <p>Increases nucleotide incorporation in lymphocytes.</p> Signup and view all the answers

    What is the significance of the G1 checkpoint in mammalian cells?

    <p>Triggers cell division.</p> Signup and view all the answers

    How do infections affect cell cultures according to the text?

    <p>Stimulate lymphocytes to divide rapidly.</p> Signup and view all the answers

    What is the protein that is synthesized at specific times during the cell cycle and associates with a kinase to form a catalytically active complex?

    <p>MPF</p> Signup and view all the answers

    Which protein, maintained at constant levels throughout the cell cycle, requires cyclin to become catalytically active?

    <p>cyclin</p> Signup and view all the answers

    What triggers the cell's passage past the G2 checkpoint into mitosis?

    <p>MPF</p> Signup and view all the answers

    Which one of the following is NOT a correct match between the protein and its role in the cell cycle?

    <p>Cdk - Inhibits cell division</p> Signup and view all the answers

    During which phase of the cell cycle is cyclin maintained at constant levels?

    <p>G1 phase</p> Signup and view all the answers

    What is the main function of spindle microtubules that do not attach to kinetochores?

    <p>Maintaining the area where fibers overlap in the cell's center</p> Signup and view all the answers

    How can radiolabeled nucleotides be used to track their incorporation into newly forming DNA?

    <p>To identify the exact location where DNA synthesis initiates</p> Signup and view all the answers

    What is the primary purpose of introducing labeled T nucleotides into a culture of dividing human cells at specific times?

    <p>To monitor the incorporation of nucleotides into newly forming DNA</p> Signup and view all the answers

    Which aspect of cellular activity is NOT directly related to spindle microtubules during mitosis?

    <p>Initiation of DNA replication</p> Signup and view all the answers

    Why is it significant to introduce labeled T nucleotides into a culture of dividing human cells when studying DNA synthesis?

    <p>To track and analyze how nucleotides are integrated into replicating DNA</p> Signup and view all the answers

    In the context of monitoring DNA replication, what information can be obtained by tracking the incorporation of radiolabeled nucleotides?

    <p>The timing and duration of specific phases in the cell cycle</p> Signup and view all the answers

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