Cell Biology Size Scales Summary

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16 Questions

What is the size of a 'typical' vertebrate cell?

10 μm

What is the size of ribosomes?

25 nm

What is the resolution of the light microscope?

0.2 μm

What method can be used to localize proteins in fixed cells?

Immunofluorescence microscopy

What technique transformed cell biological studies by allowing localization of specific proteins in living cells?

Fusing proteins to green fluorescent protein (GFP)

What does TEM allow one to see in cells?

Very fine detail such as ribosomes and membranes

Where is the genetic material (DNA) located in prokaryotes?

In the cytoplasm

What encloses the genetic material (DNA) in Eukaryotic cells?

Double membrane

What is the function of mitochondria in the cell?

Produce ATP

Where are chloroplasts found?

Only in plants

What do the endoplasmic reticulum and Golgi apparatus have in common?

Both are membrane-bound organelles

What accounts for about 50% of the cell volume?

Cytosol

What provides a dynamic three-dimensional framework in the cell?

Cytoskeleton

What do mitochondria and chloroplasts probably evolve from?

'Engulfed bacteria'

What is the major protein in microtubules?

'Tubulin'

What is the function of the plasma membrane in a cell?

'Encloses the cell'

Learn about the important size scales in cell biology, from meters down to nanometers, and the varying sizes of cells, bacteria, organelles, and atoms. Explore the concept of resolving power and the ability to distinguish close objects using the unaided eye, light microscope, and electron microscope.

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