Cell Biology Review Part 1

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Questions and Answers

What is the primary function of the cell nucleus?

  • Regulation of transport across the membrane
  • Energy production
  • Storage of genetic material (correct)
  • Synthesis of proteins

Which organelle is primarily involved in energy production within the cell?

  • Ribosome
  • Golgi apparatus
  • Mitochondrion (correct)
  • Lysosome

Which statement correctly describes the function of the plasma membrane?

  • It exclusively allows all substances to pass freely.
  • It regulates transport and maintains cellular homeostasis. (correct)
  • It synthesizes cellular proteins.
  • It is solely involved in cell division.

What is a key characteristic of eukaryotic cell division?

<p>It involves complex processes like mitosis and cytokinesis. (B)</p> Signup and view all the answers

Which component of the cell is primarily responsible for protein synthesis?

<p>Ribosome (A)</p> Signup and view all the answers

What is the main distinguishing feature of eukaryotic cells compared to prokaryotic cells?

<p>Eukaryotic cells are generally larger and have membrane-bound organelles. (A)</p> Signup and view all the answers

What role do membrane-associated proteins play in the cell membrane?

<p>They determine cell function by serving as enzymes and receptors. (D)</p> Signup and view all the answers

Which of the following correctly defines the cytoplasm of a eukaryotic cell?

<p>The part of the cell that lies between the plasma membrane and the nuclear envelope. (C), The fluid component surrounding organelles within the cell. (B)</p> Signup and view all the answers

What is true about viruses in relation to living organisms?

<p>They do not possess the characteristics of living organisms. (C)</p> Signup and view all the answers

Which of the following describes the main function of the cell membrane?

<p>To serve as a selective barrier and support membrane proteins. (B)</p> Signup and view all the answers

What is found within the cytosol of eukaryotic cells?

<p>Dissolved ions and macromolecules, including proteins. (A)</p> Signup and view all the answers

Which structure is NOT found in prokaryotic cells?

<p>Nucleus (D)</p> Signup and view all the answers

What is one of the functions of lysosomes in eukaryotic cells?

<p>Digestion of macromolecules and cellular debris. (B)</p> Signup and view all the answers

What is the main function of the Rough Endoplasmic Reticulum (rER)?

<p>Protein synthesis (D)</p> Signup and view all the answers

Which of the following statements about the Smooth Endoplasmic Reticulum (sER) is true?

<p>It is involved in the metabolism of drugs and toxins. (D)</p> Signup and view all the answers

How are proteins delivered to the Golgi body from the Rough Endoplasmic Reticulum?

<p>Via transport vesicles (A)</p> Signup and view all the answers

Which structure is primarily responsible for processing and packaging proteins?

<p>Golgi body (C)</p> Signup and view all the answers

What occurs to processed proteins after they leave the Golgi complex?

<p>They are moved into the cytosol or transported to the plasma membrane. (D)</p> Signup and view all the answers

Which of the following describes the structure of the Golgi body?

<p>Series of flattened membrane-bound sacs (B)</p> Signup and view all the answers

The Smooth Endoplasmic Reticulum lacks what feature?

<p>Ribosomes on its surface (C)</p> Signup and view all the answers

What is a primary function of the Golgi body in relation to proteins?

<p>It modifies and sorts proteins for delivery. (A)</p> Signup and view all the answers

What is one of the primary functions of the cytoskeleton in cells?

<p>Facilitate intracellular transport of organelles (D)</p> Signup and view all the answers

Which class of cytoskeletal proteins is NOT responsible for positioning the nucleus?

<p>Ribosomal proteins (A)</p> Signup and view all the answers

What is the primary function of ribosomes within a cell?

<p>Synthesize proteins from mRNA (C)</p> Signup and view all the answers

What distinguishes fixed ribosomes from free ribosomes?

<p>Fixed ribosomes are attached to the rough Endoplasmic Reticulum (A)</p> Signup and view all the answers

Which cytoskeletal component is primarily involved in transport and mitosis?

<p>Microtubules (B)</p> Signup and view all the answers

What role do actin microfilaments play in a cell?

<p>They provide structural support (C)</p> Signup and view all the answers

Which statement about free ribosomes is accurate?

<p>They can move throughout the cytosol (C)</p> Signup and view all the answers

What is the main composition of ribosomes?

<p>Ribosomal RNA and proteins (D)</p> Signup and view all the answers

What is the primary function of mitochondria?

<p>Generation of adenosine triphosphate (ATP) (B)</p> Signup and view all the answers

Which cellular process is not typically associated with mitochondria?

<p>Digestion of nucleic acids (B)</p> Signup and view all the answers

What characteristic is NOT seen in mitochondria?

<p>Produces lysosomal enzymes (C)</p> Signup and view all the answers

What do lysosomes primarily contain?

<p>Acid hydrolases (B)</p> Signup and view all the answers

Which function is not associated with lysosomes?

<p>Production of ATP (C)</p> Signup and view all the answers

How do lysosomes contribute to cellular health?

<p>By breaking down waste materials (C)</p> Signup and view all the answers

What type of compounds do lysosomes digest?

<p>Most chemical compounds including nucleic acids (D)</p> Signup and view all the answers

Which process is directly facilitated by mitochondria?

<p>Oxidative phosphorylation (C)</p> Signup and view all the answers

What structure is responsible for packaging DNA into nucleosomes?

<p>Histone proteins (D)</p> Signup and view all the answers

Which process is essential for ensuring that genetic information is accurately passed to daughter cells?

<p>Cell division (D)</p> Signup and view all the answers

What role do cyclin dependent kinases (CDKs) play in cellular functions?

<p>Control cell growth and division (D)</p> Signup and view all the answers

What is a consequence of dysregulation of growth in cells?

<p>Uncontrolled proliferation and cancer (B)</p> Signup and view all the answers

What is the main purpose of the cell cycle?

<p>To coordinate cell division and growth (C)</p> Signup and view all the answers

How does chromatin form from DNA?

<p>By wrapping around histone proteins (D)</p> Signup and view all the answers

What factor can trigger cell division in an organism?

<p>Increased demand for new cells (B)</p> Signup and view all the answers

What is the structure that carries genetic information within a cell?

<p>Chromosomes (B)</p> Signup and view all the answers

What stages are interphase during the cell cycle?

<p>G1 + S + G2 (A)</p> Signup and view all the answers

Flashcards

Cell Structure

The major components of a cell, including the cytoplasm, organelles, and nucleus.

Cytoplasm and Organelles

The region inside the cell membrane, excluding the nucleus, that contains various organelles with specific functions.

Cell Nucleus

The control center of the cell, containing the genetic material (DNA).

Eukaryotic Cell Division

The process by which a eukaryotic cell divides into two daughter cells.

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Plasma Membrane

The outer boundary of the cell, regulating the passage of substances in and out of the cell.

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Prokaryotic cells

Bacteria cells, the simplest type of cell.

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Eukaryotic cells

Cells with a nucleus and membrane-bound organelles, like animal and plant cells.

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Cell membrane

Phospholipid bilayer that surrounds cells and regulates what enters and leaves.

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Cytoplasm

The jelly-like substance inside the cell membrane, excluding the nucleus.

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Cytosol

The fluid portion of the cytoplasm, containing water, ions, and molecules.

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Mitochondria

The powerhouses of the cell, producing energy.

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Nucleus

The control center of the cell, containing DNA.

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Viruses

Not cells; not considered living organisms.

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Cytoskeleton

A network of protein fibers that provides support, shape, and movement to cells. It also helps organize organelles.

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Actin Microfilaments

Thin filaments made of the protein actin that are involved in cell shape, movement, and muscle contraction.

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Microtubules

Hollow tubes made of the protein tubulin that are involved in cell division, movement, and transport of organelles.

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Intermediate Filaments

Strong, rope-like fibers that provide structural support and help to position the nucleus.

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Ribosomes

Small organelles that synthesize proteins based on instructions from messenger RNA (mRNA).

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Free Ribosomes

Ribosomes that move freely in the cytoplasm and synthesize proteins for use within the cell.

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Fixed Ribosomes

Ribosomes attached to the endoplasmic reticulum, producing proteins for secretion or integration into the cell membrane.

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Rough Endoplasmic Reticulum (rER)

A network of membrane-bound sacs and tubules studded with ribosomes, involved in protein synthesis and modification.

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Rough ER

A network of flattened sacs with attached ribosomes, responsible for protein synthesis.

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Smooth ER

A network of flattened sacs without ribosomes, involved in lipid, steroid, and carbohydrate synthesis, as well as detoxifying substances.

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Golgi Body Structure

A series of flattened sacs that process and package proteins.

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Golgi Body Function

The Golgi body processes and packages proteins into vesicles for release or use by the cell.

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What does rER produce?

The rough endoplasmic reticulum produces proteins.

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What does sER synthesize?

The smooth endoplasmic reticulum synthesizes lipids, steroids, and carbohydrates.

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What is the role of transport vesicles?

Transport vesicles move proteins from the rER to the Golgi body.

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What is the function of secretory vesicles?

Secretory vesicles release processed proteins from the Golgi body.

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Mitochondria: Shape

Mitochondria are dynamic organelles that can change their shape, split (fission), merge (fusion), and move around inside the cell.

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Mitochondrial Genome

Mitochondria have their own DNA, called mtDNA, which is circular in shape.

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Mitochondria's Main Job

The primary function of mitochondria is to generate energy (ATP) through oxidative phosphorylation.

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Mitochondria: Other Roles

Besides energy production, mitochondria are involved in programmed cell death (apoptosis), signaling, cell differentiation, and growth.

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Lysosomes: Function

Lysosomes are responsible for breaking down most chemical compounds within the cell, including nucleic acids, carbohydrates, proteins, and lipids.

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Lysosome Contents

Lysosomes are membrane-bound sacs containing enzymes called acid hydrolases.

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Lysosome Origin

Lysosomes break down both substances produced by the cell itself and those taken in from outside.

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Lysosomes: Endocytosis/Phagocytosis

Lysosomes digest substances that enter the cell through endocytosis (engulfing small particles) or phagocytosis (engulfing large particles like bacteria).

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Nucleus Function

The nucleus is the control center of the cell, responsible for storing and protecting genetic information (DNA) and directing protein synthesis.

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Nucleolus Function

The nucleolus is a dense region within the nucleus where ribosomal RNA (rRNA) is synthesized, a key component for protein production.

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DNA Condensation

DNA molecules are incredibly long and are packaged tightly around histone proteins to form nucleosomes. These nucleosomes further condense into chromatin fibers, allowing the massive amount of DNA to fit within the nucleus.

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Cell Division Purpose

Cells divide and multiply for growth, repair, and to meet increased demands. This process allows organisms to develop, heal wounds, and maintain tissues.

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Cell Division Requirement

Before a cell can divide, it must accurately duplicate its entire genetic information (DNA) to ensure each daughter cell inherits a complete set of chromosomes.

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Cell Cycle Regulation

The cell cycle is a tightly controlled process, with key proteins called cyclin-dependent kinases (CDKs) regulating cell growth and division.

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Dysregulated Growth

If the cell cycle is not properly regulated, it can lead to uncontrolled cell proliferation and the development of cancer.

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What is this process?

The image shows the process of cell division, where a single cell divides into two daughter cells.

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Study Notes

Cell Biology Review 1

  • Learning Objectives:
    • Describe the major structural components of the cell
    • Outline the structure and function of the cytoplasm and its organelles
    • Explain the structure and function of the cell nucleus
    • Outline the process of eukaryotic cell division and its regulation
    • Describe the structure and function of the plasma membrane including how transport across the membrane is regulated
    • Outline the structural-functional relationships of different cell types

What are Cells?

  • Structural and functional units of all living things
  • Prokaryotic cells (bacteria): simple
  • Eukaryotic cells (animal and plant cells): larger, more complex, have a nucleus and membrane-bound organelles
  • Viruses are not cells, not living organisms

Eukaryotic Cell Overview

  • Cell membrane (plasma membrane): outer boundary
  • Cytoskeleton: gives shape, support, and movement
  • Mitochondria: produce ATP (energy)
  • Lysosomes: contain enzymes for digestion
  • Cytoplasm: all the material inside the cell membrane, excluding the nucleus
  • Cytosol: fluid portion of the cytoplasm
  • Golgi Body : modifies, sorts, and packages proteins
  • Rough Endoplasmic Reticulum (RER): protein synthesis
  • Smooth Endoplasmic Reticulum (SER): lipid synthesis, detoxification
  • Ribosomes: protein synthesis
  • Nucleus: controls cell activities, contains DNA
  • Nucleolus: site of ribosome assembly
  • Chromatin: DNA-protein complex

Functions of Cellular Structures

  • Cell Membrane: Fluid phospholipid bilayer, barrier and regulates transport
  • Cytoplasm and Cytosol: Cytoplasm is everything inside. Cytosol is the fluid portion with dissolved ions and macromolecules.
  • Cytoskeleton: Gives shape, maintains polarity, organizes organelles
  • Ribosomes: Synthesize proteins
  • Free ribosomes are in the cytosol.
  • Endoplasmic Reticulum (ER):
  • Rough ER: protein synthesis, ribosomes attached.
  • Smooth ER: lipid, steroid, and some carbohydrate synthesis; detoxification.
  • Golgi Body: Processes, packages, and delivers proteins.
  • Mitochondria: Produces ATP via oxidative phosphorylation
  • Lysosomes: Digest waste and foreign materials
  • Nucleus and Nucleolus: Nucleus controls cell activities, contains DNA. Nucleolus assembles ribosomes.
  • DNA: DNA in chromosomes is wrapped, around histone proteins, becoming nucleosomes, which pack to form chromatin fibers. This condensation makes the DNA much more compact.
  • Cell Cycle: Cells divide to grow and repair. Cells only divide when genetic material (DNA) has been accurately duplicated. The genetic material is equally distributed between two daughter cells.

Summary of Cell Cycle

  • Cell cycle is regulated; CDKs regulate cell growth and division. Dysregulation leads to uncontrolled proliferation and cancer.

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