Cell Biology (PB 121) - Gene Expression and Regulation Lecture

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What is the main function of DNA ligase in DNA synthesis?

Seals the single-strand nick between the nascent chain and Okazaki fragments

What is the function of methylation of histones in gene expression?

Mutes gene expression

Which type of RNA is involved in linking mRNA codons to corresponding amino acids?

Transfer RNA (tRNA)

In which phase of the cell cycle does DNA synthesis occur?

S phase

What is the main function of micro RNA (miRNA) in gene regulation?

Regulates protein expression

Which type of cells contain 40S and 60S ribosomal subunits?

Eukaryotic cells

Which enzyme is responsible for initiating the synthesis of RNA primers during replication?

DNA primase

What is the main function of helicases in the replication process?

Relieve torsional strain in DNA

What role do single-strand binding proteins (SSBs) play in DNA replication?

Prevent reannealing of ssDNA strands

Which class of proteins is involved in deoxynucleotide polymerization during DNA replication?

Helicases

What is the purpose of topoisomerase in DNA replication?

Relieve torsional strain in DNA

Which step involves the identification of the origins of replication in eukaryotic DNA?

Removal of nucleosomes & unwinding of dsDNA

Test your knowledge on gene expression and regulation in cell biology with this quiz from the First level-Pharm D Lecture 4. Topics covered include replication, transcription, translation, and the central dogma of the cell.

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