Cell Biology: Nondisjunction and the Cell Cycle
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Questions and Answers

What does nondisjunction of chromosomes mean?

  • Duplicating DNA
  • Formation of end cells
  • Failure of chromosomes to separate (correct)
  • Abnormal transverse division of chromosomes
  • During the G1 stage, the cell performs its specialized functions and does not divide.

    True

    What are the four stages of inter-phase?

    G0, G1, S, G2

    What is formed during the S-stage of the cell cycle?

    <p>DNA is duplicated.</p> Signup and view all the answers

    What happens during the G2 stage?

    <p>Chromatids join at the centromere and centrioles are duplicated.</p> Signup and view all the answers

    The abnormal transverse division of chromosomes is known as ________.

    <p>isochromosomes</p> Signup and view all the answers

    How many centrioles are present in the cell in G2-Stage?

    <p>4</p> Signup and view all the answers

    Study Notes

    Nondisjunction

    • Nondisjunction is the failure of chromosomes or chromatids to separate properly during cell division.
    • This results in one daughter cell having extra chromosomes and the other having fewer.

    Isochromosomes

    • Isochromosomes form due to abnormal transverse division of the chromosome instead of longitudinal division.
    • The resulting chromosomes have four short arms or four long arms.
    • The sticky ends of these chromosomes join together to form a ring chromosome.

    The Cell Cycle

    • The cell cycle consists of the mitotic period (cell division) and interphase (rest and preparation).
    • Interphase is further divided into G0, G1, S, and G2 stages.

    G0 Stage

    • Cells may exit the cell cycle during G0 and re-enter later.
    • Cells that stay in G0 permanently are called end cells and do not divide further.

    G1 Stage

    • The period between the end of mitosis and the beginning of S-stage.
    • Each daughter cell has 46 chromatids called interphase chromosomes (S-chromosomes).

    S Stage

    • The cell duplicates its DNA during this stage.
    • Each cell now has 92 S-chromosomes.

    G2 Stage

    • A short period between S-stage and the beginning of mitosis.
    • Identical pairs of chromatids join at the centromere to form d-chromosomes.
    • The number of centrioles and the amount of tubulin protein increase.
    • By the end of G2, the cell contains 46 pairs of identical chromatids (d-chromosomes) and 4 centrioles.

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    Description

    Explore the crucial concepts of nondisjunction, isochromosomes, and the various stages of the cell cycle, including G0 and G1. This quiz covers important definitions and details that are essential for understanding chromosomal behavior during cell division. Test your knowledge and grasp these fundamental biological principles.

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