Cell Biology MD 201: Cell Theory & Structure

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Questions and Answers

Considering the historical context surrounding the formulation of the cell theory, what was the MOST substantial paradigm shift that enabled its eventual acceptance, overcoming the limitations imposed by prevailing scientific beliefs?

  • The refinement of microscopic lenses, which provided the necessary resolution to observe cellular division.
  • The advent of advanced staining techniques that allowed for better visualization of cellular structures, disproving spontaneous generation.
  • The integration of experimental observations with a theoretical framework that supported the concept of biogenesis. (correct)
  • The widespread adoption of germ theory, which provided a causal mechanism for the origin of cells from pre-existing cells.

In the context of the modern cell theory, which statement provides the MOST comprehensive explanation for the observed diversity in cellular function across various cell types within a multicellular organism?

  • Variations in the lipid composition of the plasma membrane create functional differences between cell types.
  • All cells possess the same basic machinery, but differential gene expression patterns dictate the unique functional profiles of specialized cells. (correct)
  • The presence or absence of specific organelles determines the functional specialization of different cell types.
  • Differences in the total amount of DNA in each cell type account for the observed functional diversity.

Considering the principle that cells are the basic structural and functional units of life, what experimental approach would MOST effectively refute the claim that a newly discovered, self-replicating vesicle should be classified as a living entity?

  • Demonstrating that the vesicle lacks the ability to perform metabolic reactions.
  • Showing that the vesicle cannot maintain a stable internal environment (homeostasis). (correct)
  • Proving that the vesicle does not contain DNA or RNA.
  • Establishing that the vesicle is unable to evolve or adapt to changing environmental conditions.

If an alien life form was discovered with a different hereditary molecule than Earth-based organisms, which statement below would MOST meaningfully challenge the universality of the modern cell theory?

<p>If the alien organism demonstrates emergent properties solely from interactions between its constituent molecules, without compartmentalization. (A)</p> Signup and view all the answers

If spontaneous generation were proven to be true under specific circumstances, which tenet of the cell theory would require the MOST extensive revision, and what implications would this have for our understanding of biology.

<p>The tenet that all cells arise from pre-existing cells; this would disrupt our understanding of evolutionary and developmental biology. (D)</p> Signup and view all the answers

Given that cell theory provides a foundational framework for understanding life, what inherent limitation does cell theory impose on our comprehension of abiogenesis and the transition from non-living matter to cellular life?

<p>Cell theory presupposes a pre-existing cellular state, thus it cannot fully explain how the first cells originated from non-cellular components. (B)</p> Signup and view all the answers

Considering the metabolic capabilities of cells, which biochemical process provides the MOST compelling evidence for the evolutionary conservation of fundamental life processes across all three domains of life (Archaea, Bacteria, and Eukarya)?

<p>The utilization of a universal genetic code for protein synthesis. (C)</p> Signup and view all the answers

Imagine the discovery of a novel cellular structure within a eukaryotic cell that is NOT derived from the endomembrane system and does not contain DNA. What experimental approach would be MOST appropriate to determine its evolutionary origin and function?

<p>Compare its protein sequence to those of known bacterial proteins. (C)</p> Signup and view all the answers

Considering that cell size is constrained by surface area-to-volume ratios, which cellular adaptation would MOST effectively overcome these constraints in a metabolically active cell requiring high rates of nutrient exchange and waste removal?

<p>Developing a flattened or elongated morphology with extensive membrane folding. (D)</p> Signup and view all the answers

Given the evolutionary pressures on cells to maintain genomic integrity, what mechanism do cells employ to deal with DNA damage?

<p>The use of homologous recombination repair pathways during DNA replication. (A)</p> Signup and view all the answers

Many laboratory experiments were key to developing cell theory, for example Pasteur disproved spontaneous generation. What was the MOST important aspect of Pasteur's experimental design that allowed him to effectively disprove spontaneous generation?

<p>Using swan-necked flasks to prevent airborne particles from entering the broth, while allowing air exchange. (D)</p> Signup and view all the answers

Consider a hypothetical situation where a new type of cell is discovered that violates the third tenet of cell theory. What might this cell look like?

<p>A cell that can arise from non-cellular material through a process resembling crystallization. (D)</p> Signup and view all the answers

If a biologist discovers a new organism that does not contain cells, what would be the MAIN implications for cell theory and evolutionary biology?

<p>Cell theory may not be universally applicable to all life forms. (A)</p> Signup and view all the answers

What key role did Anton van Leeuwenhoek's lenses play in biology?

<p>Were able to observe single-celled organisms ('animalcules') with unprecedented clarity. (A)</p> Signup and view all the answers

Given the characteristics of cells, which property is essential for maintaining structural integrity and facilitating interactions with the extracellular environment and other cells?

<p>The presence of a plasma membrane. (D)</p> Signup and view all the answers

How do cells self-regulate?

<p>Through feedback mechanisms that maintain internal stability and respond to stimuli. (B)</p> Signup and view all the answers

Many animal cells specialize, taking different shapes and functions according to their purpose. What is the primary mechanism by which cells with the same genetic material can exhibit such striking differences in function and morphology?

<p>Epigenetic modifications. (C)</p> Signup and view all the answers

What is the major difference between prokaryotic and eukaryotic cells?

<p>Eukaryotic cells possess a membrane-bound nucleus and complex organelles, while prokaryotic cells lack these features. (D)</p> Signup and view all the answers

What is the significance of ribosomes in both prokaryotic and eukaryotic cells?

<p>They are responsible for protein synthesis. (A)</p> Signup and view all the answers

If a drug was developed to specifically target and inhibit the function of the Golgi apparatus, which cellular process would be MOST directly affected?

<p>Protein modification and sorting. (B)</p> Signup and view all the answers

How would we classify protozoa?

<p>Eukaryotes that are unicellular. (A)</p> Signup and view all the answers

If a researcher is studying the process of exocytosis in a cell, what aspect of cell biology are they PRIMARILY focused on?

<p>Cell's ability to transport molecules across membranes. (A)</p> Signup and view all the answers

Which cellular component is responsible for generating energy through cellular respiration?

<p>Mitochondria. (C)</p> Signup and view all the answers

What is the role of the cell wall for cells?

<p>To provide structural support and protection. (A)</p> Signup and view all the answers

What implications would a cell's inability to acquire and utilize energy have?

<p>It would violate cell theory. (B)</p> Signup and view all the answers

What aspect of the cell do 'signal transduction' processes affect?

<p>How cells sense and respond to external cues. (B)</p> Signup and view all the answers

What could be seen as a challenge to cell theory from newly discovered organisms?

<p>Organisms that do not contain DNA. (D)</p> Signup and view all the answers

How would you describe 'cell biology'?

<p>The study of cells. (C)</p> Signup and view all the answers

Why is it important that cells can replicate independently?

<p>To allow for growth and repair. (C)</p> Signup and view all the answers

Which of the following cell characteristics is MOST associated with 'growth'?

<p>Replicating independently. (C)</p> Signup and view all the answers

What would be the BEST example of tissues performing 'mechanical activities'?

<p>Muscle contraction. (A)</p> Signup and view all the answers

If it was found that spontaneous generation DOES occur, what scientists that contributed towards cell theory would that realization negate?

<p>Louis Pasteur. (A)</p> Signup and view all the answers

What are some of the main components of cells?

<p>All of the above. (D)</p> Signup and view all the answers

If a cell theory was proposed that stated cells were NOT the basic unit of life, what would have to be shown about cells?

<p>That cells are dependent on other structures. (B)</p> Signup and view all the answers

What implications did Schleiden and Schwann NOT contribute to cell theory?

<p>All matter is made of cells. (B)</p> Signup and view all the answers

How would you BEST describe the statement 'Cells vary from individual single cell organisms (bacteria) to multi structures (tissues, organs) and organisms (animals and plants)'?

<p>An example of how cells differ based on their structure. (B)</p> Signup and view all the answers

What is an important fact about cell division?

<p>The cell contains hereditary information, which is passed on from cell to cell during cell division. (B)</p> Signup and view all the answers

How can cells respond to external stimuli?

<p>Through self-regulation. (B)</p> Signup and view all the answers

Flashcards

What is a cell?

The basic structural and functional unit of all living organisms.

What is Cell Biology?

The branch of biology studying cells, including their structure, function, and organization.

Biological organization

Cells join together in a coordinated fashion to form tissue, tissue structures aggregate to produce organs, groups of organs interact in organ systems and they constitute the individual anatomy.

Who is Robert Hooke?

Observed cells in cork slices under a microscope and named them "cells" in 1665.

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Who is Anton van Leeuwenhoek?

Observed single-celled organisms and called them 'animalcules'.

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Cell Theory: 1st Point

All living organisms are composed of one or more cells.

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Cell Theory: 2nd Point

The cell is the basic unit of life in all living things.

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Cell Theory: 3rd Point

All cells are produced by the division of pre-existing cells.

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Modern Cell Theory: Heredity

Cells contain hereditary information (DNA) passed during cell division.

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Modern Cell Theory: Composition

All cells are similar in chemical composition and metabolic activities.

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Modern Cell Theory: Functions

Basic chemical and physiological functions are carried out inside cells.

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Modern Cell Theory: Activity

Cell activity depends on subcellular structures.

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What is Catabolism?

A process where complex molecules are broken down into simpler ones to release energy.

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What is Anabolism?

A process where simple molecules are combined to form complex ones, requiring energy.

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What are Eukaryotic cells?

Cells that contain a nucleus and other complex organelles.

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What are Prokaryotic cells?

Single celled organisms with no nucleus or membrane bound organelles.

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Eukaryotes features

Cells that can be single-celled or multicellular, contain a nucleus and organelles, and reproduce sexually or asexually.

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Prokaryotes features

The characteristics of cells including cell membrane and asexually reproduction via binary fission

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Study Notes

Cell Biology MD 201

  • The course covers cell theory, structure, and function.
  • Topics include the cell wall, plasma membrane, and cell components.
  • Cell components include: centrioles, chloroplasts, cytoskeleton, endoplasmic reticulum, lysosomes, Golgi apparatus, mitochondria, ribosomes, and the nucleus.
  • Further study in cell growth, proliferation, apoptosis, cancer, exocytosis and endocytosis.
  • Focus on the transport of biological molecules, membrane function, signal transduction, cell signaling, and quorum sensing.
  • Lecture topics include Cell theory, Cell types, Cell wall, Cell membrane ,Cell organelles, Nucleus, DNA structure, DNA replication, Membrane transport, Cell signaling, Cell cycle, Cell division, Cancer and abnormal cell growth.
  • Grading consists of a Midterm(10%), Practical(20%), Final(50%), Oral(10%), Quizzes(5%), and Class Activity(5%).
  • Credit hour is (1+1), lecture time is 60 min, and the final exam time is 1 hour.

Cell & Cell Theory

  • A cell is the basic structural and functional unit of all living organisms.
  • It is the smallest unit of life and replicates independently.
  • The study of cells is called Cell Biology.
  • Cells range from single-celled organisms like bacteria to multicellular structures like tissues, organs, animals, and plants.
  • The average human is composed of around 100 trillion cells.
  • Cell biology deals with the study of structure, function, molecular organization, growth, reproduction, and genetics of cells
  • It is mainly concerned with the study of the structure of cells and the function of specialized cells.
  • Robert Hooke discovered cells in 1665 using a microscope.
  • Hooke observed cells in thin slices of bottle cork.
  • He named the tiny pores he saw "cells" from the Latin word "Colla," which means small room.
  • Anton van Leeuwenhoek used a handmade microscope in 1673 to look at pond scum and discovered single-celled organisms.
  • Leeuwenhoek called the single-celled organisms "animalcules."
  • He observed blood cells from fish, birds, frogs, dogs, and humans.
  • Spontaneous Generation delayed advancements in cell study between Hooke/Leeuwenhoek's discoveries and the mid-19th century.
  • Louis Pasteur disproved spontaneous generation in the 19th century.
  • In 1838, Matthias Schleiden, a German botanist, stated that all plant parts are made of cells.
  • In 1839, Theodor Schwann, a German physiologist determined that all animal tissues are composed of cells.
  • In 1858, Rudolf Virchow, a German physician, concluded that cells must arise from preexisting cells after studying cellular pathology extensively.

Cell Properties

  • Cells are highly complex and organized.
  • Cells possess a genetic program and the means to use it.
  • They are capable of producing more of themselves.
  • Cells acquire and utilize energy and carry out a variety of chemical reactions.
  • They engage in mechanical activities.
  • Cells are able to respond to stimuli and are capable of self-regulation.

Cell Theory

  • All organisms are composed of one or more cells.
  • The cell is the basic unit of life in all living things.
  • All cells are produced by the division of preexisting cells.

Modern Cell Theory

  • It contains 4 statements in addition to the original cell theory.
  • Cells contain hereditary information (DNA) is passed from cell to cell during cell division.
  • All cells are the same in chemical composition and metabolic activities.
  • All basic chemical and physiological functions are carried out inside the cells (movement, digestion, etc.).
  • Cell activity varies based on the activities of subcellular structures.
  • Sub-cellular structures that make up cell activity include organelles, nucleus, and plasma membrane.

Eukaryotes versus Prokaryotes

  • Eukaryotes are either single-celled or multi-celled organisms.
  • They have a nucleus and organelles.
  • Eukaryotes have a cell membrane.
  • They reproduce by both sexual and asexual reproduction (meiosis and mitosis).
  • Prokaryotes are single-celled organisms only.
  • They do not have a nucleus or other organelles except ribosomes.
  • Prokaryotes contain a cell membrane and cell wall.
  • They reproduce only by asexual reproduction (binary fission).

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