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Questions and Answers
What does the G2 checkpoint primarily assess?
What does the G2 checkpoint primarily assess?
- The number of chromosomes present
- Availability of nutrients and growth factors
- Cell size and metabolic activity
- The integrity of DNA and completeness of DNA replication (correct)
What happens if the G2 checkpoint detects DNA damage?
What happens if the G2 checkpoint detects DNA damage?
- Cell division occurs immediately.
- The cell attempts to repair the damage or complete replication. (correct)
- The cell continues to divide without checks.
- The cell moves to the G1 phase.
Which of the following outcomes may occur if DNA damage is irreparable during the G2 checkpoint?
Which of the following outcomes may occur if DNA damage is irreparable during the G2 checkpoint?
- The cell undergoes apoptosis. (correct)
- The cell undergoes meiosis.
- The cell continues through the cell cycle normally.
- The cell enters a prolonged G1 phase.
What role does the G2 checkpoint play in cancer prevention?
What role does the G2 checkpoint play in cancer prevention?
During the G2 checkpoint, if DNA replication is detected as incomplete, what action does the cell take?
During the G2 checkpoint, if DNA replication is detected as incomplete, what action does the cell take?
Flashcards
G2 Checkpoint
G2 Checkpoint
A cell cycle checkpoint that occurs before mitosis, checking for DNA errors and damage.
DNA Damage
DNA Damage
Impaired DNA integrity detected by the G2 checkpoint.
DNA Replication
DNA Replication
The complete copying of the DNA's genetic material during the S phase.
Cell Cycle Halt
Cell Cycle Halt
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Apoptosis
Apoptosis
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Study Notes
G2 Checkpoint
- Ensures smooth cell division, producing healthy daughter cells with undamaged DNA.
- Occurs before M phase.
- Checks for DNA integrity and replication.
- If errors/damage detected, cell pauses to repair.
- Cell cycle halted if DNA problems are detected.
- Cell attempts DNA replication completion or repair.
- Irreparable damage triggers apoptosis (programmed cell death).
- Apoptosis prevents damaged DNA from being passed to daughter cells.
- Apoptosis crucial for cancer prevention.
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