Cell Biology Basics

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Questions and Answers

What primarily drives active transport?

  • DNA
  • Pressure
  • H+
  • ATP (correct)

Lysosomes are filled with what?

  • DNA
  • Cilia
  • Blood
  • Powerful enzymes that destroy cellular debris and pathogens (correct)

What process is also known as cellular drinking?

  • Active transport
  • Exocytosis
  • Diffusion
  • Pinocytosis (correct)

Which of the following best describes normal saline?

<p>Isotonic (D)</p> Signup and view all the answers

What is the name for the process where a vesicle fuses with the cell membrane to expel its contents?

<p>Exocytosis (C)</p> Signup and view all the answers

What term describes the bursting of red blood cells?

<p>Hemolysis (D)</p> Signup and view all the answers

What term describes a lysosome eating a bacterium?

<p>Phagocytosis (A)</p> Signup and view all the answers

Where is most of a cell's DNA found?

<p>Nucleus (C)</p> Signup and view all the answers

Which of the following best describes the extensive internal membrane system that forms channels and is concerned with synthesis of proteins and steroids?

<p>Endoplasmic reticulum (B)</p> Signup and view all the answers

Which type of solution causes crenation of red blood cells?

<p>Hypertonic (D)</p> Signup and view all the answers

Which cellular structure is characterized as rough or smooth?

<p>Endoplasmic reticulum (A)</p> Signup and view all the answers

Which of the following best describes phagocytosis and pinocytosis?

<p>Endocytosis (B)</p> Signup and view all the answers

What is the gel-like substance inside a cell, outside the nucleus called?

<p>Cytoplasm (C)</p> Signup and view all the answers

Which of the following most accurately describes diffusion?

<p>Passive transport (A)</p> Signup and view all the answers

Prophase, metaphase, anaphase, and telophase are phases of what?

<p>Mitosis (B)</p> Signup and view all the answers

What organelle puts the finishing touches on proteins and packages them for export?

<p>Golgi apparatus (A)</p> Signup and view all the answers

Plasma oncotic pressure is also known as what type of pressure?

<p>Osmotic pressure (C)</p> Signup and view all the answers

What condition may develop if plasma protein leaks into the tissue spaces?

<p>Edema (C)</p> Signup and view all the answers

Mitosis results in the production of how many cells, and what is their genetic relationship?

<p>Two genetically identical cells (D)</p> Signup and view all the answers

During which phase of the cell cycle do the G1, G2, and S phases occur?

<p>Interphase (A)</p> Signup and view all the answers

An anticancer drug that only interferes with mitosis is what?

<p>Cell cycle M phase–specific (D)</p> Signup and view all the answers

Cell division occurs during which phase of the cell cycle?

<p>M phase (B)</p> Signup and view all the answers

What is the name for when a cell 'drops out' of the cell cycle?

<p>G0 (C)</p> Signup and view all the answers

Which of the following best describes a necrotic cell?

<p>Dead (D)</p> Signup and view all the answers

Which process is the RER primarily involved with?

<p>Phagocytosis (B)</p> Signup and view all the answers

A beaker has two compartments (A and B) with a membrane permeable to salt and water. Compartment A has 10% salt, and Compartment B has 20% salt. At equilibrium, what is true?

<p>The volume is the same in both compartments (A)</p> Signup and view all the answers

A beaker has two compartments (A and B) with a membrane permeable only to water. Compartment A has 10% salt, and Compartment B has 20% salt. At equilibrium, what is true?

<p>The volume in A is less than the volume in B (A)</p> Signup and view all the answers

Most potassium ($K^+$) is located inside cells. What accounts for the movement of additional $K^+$ into the cells?

<p>$K^+$ is actively pumped into the cell (C)</p> Signup and view all the answers

A child experiences a head injury causing a slow bleed. After the bleeding stops, the blood clot expands because...

<p>The particles of the blood clot are osmotically active and draw water into the clot (B)</p> Signup and view all the answers

What is the primary difference between diffusion and facilitated diffusion?

<p>Facilitated diffusion uses a 'helper' molecule to move a substance passively (D)</p> Signup and view all the answers

What is the effect of an intravenous infusion of pure water?

<p>The RBCs burst (C)</p> Signup and view all the answers

Which of the following describes the response of a red blood cell (RBC) to immersion in an isotonic solution?

<p>There is no net movement of water between the RBC and solution (A)</p> Signup and view all the answers

Telophase and cytokinesis are stages of what?

<p>Mitosis (D)</p> Signup and view all the answers

What do telophase and cytokinesis complete?

<p>The splitting of a single cell into two identical cells (B)</p> Signup and view all the answers

Methotrexate is most effective when a cancer cell is in which phase of the cell cycle?

<p>S phase (D)</p> Signup and view all the answers

Methotrexate interferes with cell replication, what best describes this?

<p>Cell cycle phase–specific (D)</p> Signup and view all the answers

What process is exemplified when a stem cell develops into a muscle cell?

<p>Differentiation (C)</p> Signup and view all the answers

In a scenario where Compartment A contains a 5% glucose solution and Compartment B contains a 15% glucose solution, where might the membrane (dividing the beaker into compartments A and B) be permeable to both solute and solvent? What will happen to the water's net flux initially?

<p>Water diffuses from compartment A to compartment B. (B)</p> Signup and view all the answers

If Compartment A contains a 25% glucose solution and Compartment B a 15% glucose solution, and the dividing membrane is permeable only to water, what is true regarding the initial net flux?

<p>Water diffuses from compartment B to compartment A. (D)</p> Signup and view all the answers

In which scenario would the volume in compartment B be greater than in compartment A at equilibrium, with a membrane separating them?

<p>5% glucose in A, 15% in B, membrane impermeable to solute, permeable to solvent. (A)</p> Signup and view all the answers

If a compartment A contains a 25% glucose solution and compartment B contains a 5% glucose solution, separated by a membrane permeable to solvent but not glucose, what will occur?

<p>Water will move from compartment B to compartment A. (D)</p> Signup and view all the answers

Given a capillary filtration pressure of 30 mm Hg at the arterial end and 7 mm Hg at the venous end, and a capillary oncotic pressure of 15 mm Hg, what typically happens at the arterial end of the capillary?

<p>Most water is filtered out of the capillary into the interstitium. (D)</p> Signup and view all the answers

How does potassium (K+) typically move from the extracellular compartment to the intracellular compartment to maintain the high intracellular concentration?

<p>Active transport pump (C)</p> Signup and view all the answers

What happens to a red blood cell (RBC) when it is placed in a hypertonic saline solution?

<p>The RBC will shrink. (A)</p> Signup and view all the answers

Which of the following statements about glycogen is NOT true?

<p>Glycogen is an alcohol to which three fatty acids attach thereby forming a triglyceride. (B)</p> Signup and view all the answers

Flashcards

Facilitated Diffusion

Movement of substances from an area of high concentration to an area of low concentration using a carrier molecule; requires no energy input.

Exocytosis

The process where an intracellular vesicle fuses with the cell membrane to expel its contents outside the cell.

Endocytosis

The process by which cells engulf substances, bringing them into the cell.

Hemolysis

The bursting of red blood cells.

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Hypotonic Solution

A solution with a lower solute concentration than inside the cell.

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Crenation

Cell shrinks due to water moving out.

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Hypertonic Solution

A solution with a higher solute concentration than inside the cell, causing the cell to shrink.

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Mitosis

The division of a cell's nucleus into two identical nuclei; includes prophase, metaphase, anaphase, and telophase.

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Pinocytosis

Cellular 'drinking'; the engulfing of small amounts of fluid by the cell membrane.

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Isotonic Solution

A solution with the same concentration of solutes as another solution (e.g., cell's cytoplasm).

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Phagocytosis

Cellular 'eating'; the engulfing of large particles or cells by a cell (e.g., a white blood cell engulfing bacteria).

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Nucleus

The control center of the cell; contains most of the cell's DNA.

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Cytoplasm

A gel-like substance inside the cell, outside the nucleus, where organelles are located.

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Diffusion

The movement of molecules from an area of high concentration to an area of low concentration; passive transport.

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Filtration

The pushing of water and solutes through a membrane from an area of high pressure to an area of low pressure.

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Golgi Apparatus

Packages and modifies proteins for transport; forms lysosomes.

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RER function

Phagocytosis.

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Equilibrium with permeable membrane

The volume is the same in both compartments at equilibrium.

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Equilibrium with water-permeable membrane

The volume in Compartment A (10% salt) is greater at equilibrium.

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Potassium (K+) Movement into Cells

K+ is actively pumped into the cell.

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Expanding Blood Clot

Particles of the blood clot are osmotically active and draw water into the clot, causing it to expand.

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Facilitated Diffusion vs. Diffusion

Facilitated diffusion uses a 'helper' molecule to move a substance passively.

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IV Infusion of Pure Water

The RBCs burst due to influx of water.

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RBC in Isotonic Solution

There is no net movement of water between the RBC and solution.

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Plasma Oncotic Pressure

The pressure that tends to draw water into the capillary from the tissue spaces due to plasma proteins.

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Edema Development

If plasma proteins escape into tissues, water follows, leading to swelling.

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Gap Phases (G1, G2) and Synthesis (S)

Phases of the cell cycle where the cell grows and prepares for division; (G1), (G2), and synthesis phase (S).

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Cell Cycle M Phase-Specific Drugs

Specifically targets cells during the M phase (mitosis) of the cell cycle.

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G0 Phase

A cell that exits the cell cycle and enters a state of quiescence.

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Necrotic Cell

Cell death due to injury or disease.

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Benign Neoplasm

A noncancerous growth that does not spread to other parts of the body.

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Telophase & Cytokinesis

Telophase and cytokinesis involves the splitting of a single cell into two identical cells.

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Phase-specific drugs

Cell cycle phase–specific drugs like methotrexate are most effective during specific phases of the cell cycle, such as the S phase (DNA synthesis).

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Cell Differentiation

Differentiation is the process by which a stem cell becomes a specialized cell type, such as a muscle cell.

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Water Diffusion

In initial net flux, water diffuses from a compartment with a lower solute concentration (5% glucose) to a compartment with a higher solute concentration (15% glucose).

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Osmosis with Impermeable Solute

Water diffuses from compartment B (15% glucose) to compartment A (25% glucose) because the membrane is impermeable to glucose.

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Volume Increase at Equilibrium

This would occur when there is a higher concentration of glucose in compartment B and the membrane is impermeable to glucose.

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Osmosis

Water moves from low to high solute concentration across a semipermeable membrane.

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Capillary Filtration Pressure

Pushes water out of capillaries at the arterial end; higher pressure overcomes oncotic pressure.

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Active Transport Pump

Moves substances against their concentration gradient, requiring energy (ATP).

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Glycogen

A polysaccharide that is the storage form of glucose in animals, found primarily in the liver and muscles.

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Study Notes

  • The nucleus is the control center of the cell.
  • Mitochondria are the power plants of the cell, most ATP is produced within them.
  • Ribosomes are found on the rough endoplasmic reticulum (ER).
  • The rough ER is responsible for protein synthesis.
  • Ribosomes are most associated with protein synthesis.
  • Osmosis is a passive transport mechanism where water moves from an area of high concentration to an area of low concentration.
  • Filtration is a passive transport mechanism driven by pressure differences.
  • In a beaker with two compartments (A and B) separated by a semipermeable membrane, where A has 20% NaCl and B has 50% NaCl and the membrane is permeable to water but not to Na+ or Cl-, water diffuses from compartment A to compartment B initially.
  • At equilibrium, the volume in compartment B will be greater than the volume in compartment A.
  • If the membrane is permeable to water, Na+, and Cl-, then Na+ and Cl- diffuse from compartment B to compartment A initially.
  • At equilibrium, with a membrane permeable to water, Na+, and Cl-, concentrations and volumes will be the same in both compartments.
  • Cilia are hairlike structures located on the outer surface of the cell membrane.
  • The endoplasmic reticulum is an extensive internal membrane system that forms channels and synthesizes proteins and steroids.
  • Lysosomes are filled with powerful enzymes that destroy cellular debris and pathogens.
  • ATP best describes the power or driving force for active transport.
  • Facilitated diffusion is a passive transport mechanism using a carrier molecule to move a solute from high to low concentration.
  • Exocytosis is the process where an intracellular protein-containing vesicle fuses with the cell membrane and expels the protein outside the cell.
  • Endocytosis describes phagocytosis and pinocytosis.
  • Hemolysis means the bursting of red blood cells.
  • A cell placed in a hypotonic solution such as water will swell and burst.
  • A hypertonic solution causes crenation or shrinkage of submerged red blood cells.
  • Prophase, metaphase, anaphase, and telophase are phases of mitosis.
  • G1, G2, the S phase, and the M phase are phases of the cell cycle.
  • Pinocytosis is a passive process that refers to cellular drinking.
  • Normal saline is isotonic.
  • Phagocytosis describes the eating of a bacterium by a lysosome.
  • Most DNA is found in the nucleus.
  • The endoplasmic reticulum can be rough or smooth.
  • Cytoplasm is the gel-like substance inside the cell but outside the nucleus.
  • Diffusion is passive transport.
  • A skunk makes his presence known by diffusion.
  • Oxygen moves from the lungs (high concentration) into the blood (low concentration) by diffusion.
  • Filtration describes the pushing of water across the capillary (blood vessel) membrane.
  • The Golgi apparatus puts the finishing touches on and packages proteins for export from the cell.
  • Ribosomes make the rough endoplasmic reticulum look like sandpaper.
  • The cell membrane is a semipermeable lipid bilayer.
  • The selectively permeable membrane determines which substances enter and leave the cell.
  • Most ATP is produced in the mitochondria.
  • A beaker contains two compartments, A (10% salt) and B (20% salt), separated by a membrane permeable to salt and water.
  • At equilibrium, the volume is the same in both compartments.
  • A beaker contains two compartments, A (10% salt) and B (20% salt), separated by a membrane permeable to only water: at equilibrium, the volume in CA is less than the volume in CB.
  • K+ is actively pumped into the cells.
  • Particles of a blood clot draw water into the clot due to osmotic activity.
  • Facilitated diffusion uses a "helper" molecule to move a substance passively.
  • Intravenous infusion of pure water causes RBCs to burst.
  • Red blood cells (RBC) in an isotonic solution - there is no net movement of water between the RBC and solution.
  • Plasma proteins determine plasma oncotic (osmotic) pressure.
  • If plasma protein leaks into the tissue spaces, edema develops.
  • Mitosis produces two genetically identical cells.
  • The first gap phase (G1), second gap phase (G2), and synthesis phase (S) occur during interphase.
  • An anticancer drug that interferes only with mitosis is cell cycle M phase-specific.
  • Cell division occurs during the M phase of the cecl cycle.. -A cell that "drops out" of the cell cycle enters G0.
  • A necrotic cell is dead.
  • A benign neoplasm is a noncancerous tumor.
  • Well-differentiated cells in a cervical Pap smear indicate a normal cellular appearance.
  • The mitochondrium contains the enzymes of the Krebs cycle and electron transport chain and primarily produces ATP..
  • Apoptosis is a programmed sequence of events that helps rid the body of old, unnecessary, and unhealthy cells.
  • Ribosomes, rough ER, and the Golgi apparatus are all involved in protein synthesis.
  • Prophase, metaphase, anaphase, and telophase are stages of mitosis.
  • Telophase and cytokinesis complete the splitting of a single cell into two identical cells.
  • Methotrexate, an anticancer drug that interferes with cell replication,is cell cycle phase-specific.
  • A stem cell develops into a muscle cell because of differentiation.
  • Compartment A (5% glucose) and Compartment B (15% glucose), with a membrane permeable to both solute and solvent means water diffuses from compartment A to compartment B.
  • Compartment A (25% glucose) and Compartment B (15% glucose), with a membrane permeable to water but impermeable to glucose, water diffuses from compartment B to compartment A.
  • To achieve a greater volume in compartment B at equilibrium: compartment A has a 5% glucose solution and compartment B has a 15% glucose solution, and the membrane is impermeable to the solute but permeable to the solvent.
  • Capillary filtration pressure at the arterial end (30 mm Hg) exceeds capillary oncotic pressure (15 mm Hg), most water is filtered out of the capillary into the interstitium at the arterial end of the capillary.
  • Potassium (K +) moves from the extracellular to the intracellular compartment via an active transport pump.
  • A red blood cell (RBC) in hypertonic saline will shrink.
  • Glycogen is a storage form of glucose, helps in the regulation of blood glucose, and is stored within the liver and skeletal muscle and not an alcohol.
  • A substance composed of glycerol and three fatty acids is triglyceride.

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