Cell and Molecular Biology (BIOL 4803) Final Exam
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Questions and Answers

What is the primary function of the Golgi apparatus?

  • Modification and sorting of proteins for transport (correct)
  • Energy production through ATP synthesis
  • Support of cell structure and shape
  • Lipid metabolism and detoxification
  • What is a characteristic of the mitochondrial genome?

  • Linear DNA inherited from both parents
  • Contains genes solely for lipid metabolism
  • Encodes proteins necessary for glycolysis
  • Circular DNA inherited maternally (correct)
  • Which of the following best describes the role of actin filaments in the cytoskeleton?

  • Assist in cell shape and movement (correct)
  • Form the structure of the mitotic spindle
  • Provide structural support to the cell
  • Facilitate intracellular transport
  • Which type of transport mechanism is characterized by the simultaneous movement of two substances in the same direction?

    <p>Symport system</p> Signup and view all the answers

    Which of the following is NOT a mode of cell signaling?

    <p>Esophageal</p> Signup and view all the answers

    What is the primary function of lysosomes in a cell?

    <p>Degradation of waste materials and cellular debris</p> Signup and view all the answers

    What structure in the plasma membrane is primarily responsible for its fluidity?

    <p>Cholesterol</p> Signup and view all the answers

    Which type of cytoskeletal element is primarily involved in muscle contraction?

    <p>Actin filaments</p> Signup and view all the answers

    What distinguishes mitochondrial DNA from nuclear DNA?

    <p>Mitochondrial DNA is circular and codes for a limited number of proteins</p> Signup and view all the answers

    Which mechanism involves the movement of molecules down their concentration gradient without the need for energy?

    <p>Facilitated diffusion</p> Signup and view all the answers

    Which type of signaling involves hormones released into the bloodstream affecting distant cells?

    <p>Endocrine signaling</p> Signup and view all the answers

    What is the role of heat-shock proteins (HSP) in protein processing?

    <p>Assisting in protein folding</p> Signup and view all the answers

    Which coat protein is primarily involved in vesicle transport from the Golgi apparatus to the endoplasmic reticulum?

    <p>COP1</p> Signup and view all the answers

    What is the primary function of glycosylation in protein processing?

    <p>Stabilization for proper protein function</p> Signup and view all the answers

    Where are nuclear localization signals primarily located in proteins?

    <p>At the N-terminus</p> Signup and view all the answers

    What is the function of gap junctions in cell membranes?

    <p>Facilitating direct communication between adjacent cells</p> Signup and view all the answers

    What structure is responsible for assembling ribosomal RNA and proteins into ribosome subunits?

    <p>Nucleolus</p> Signup and view all the answers

    Which statement accurately describes lipid rafts?

    <p>They serve as organizing centers for the assembly of signaling molecules</p> Signup and view all the answers

    Which of the following statements about the endoplasmic reticulum (ER) is true?

    <p>Rough ER is characterized by the presence of ribosomes.</p> Signup and view all the answers

    Which of the following is a characteristic feature of peroxisomes?

    <p>They are involved in fatty acid oxidation and detoxification</p> Signup and view all the answers

    What is the primary role of ubiquitin in protein degradation?

    <p>To tag proteins for degradation</p> Signup and view all the answers

    What type of bonds are present in cellulose?

    <p>β-1,4 glycosidic bonds</p> Signup and view all the answers

    Which structure is primarily responsible for aiding in proper protein folding?

    <p>Chaperones and heat-shock proteins</p> Signup and view all the answers

    What is the role of nucleotides in cellular function?

    <p>Energy carriers like ATP</p> Signup and view all the answers

    Which statement correctly describes the rough endoplasmic reticulum (ER)?

    <p>Ribosome-studded, facilitating protein synthesis</p> Signup and view all the answers

    What is the primary composition of the bacterial cell wall?

    <p>Peptidoglycan</p> Signup and view all the answers

    What is the function of the glycocalyx?

    <p>Facilitates cell-cell interactions and protects the cell surface</p> Signup and view all the answers

    What is the role of the nucleolus in the cell?

    <p>Synthesis of ribosomal RNA (rRNA)</p> Signup and view all the answers

    Which of the following is NOT a restructuring protein in the cell?

    <p>Glycocalyx</p> Signup and view all the answers

    Study Notes

    Cell and Molecular Biology (BIOL 4803) - Final Exam Topics Fall 2024

    • Chapter 1: Overview of Cells and Cell Research
      • Plasma membrane structure and function
        • Phospholipids (structure and where they are made)
        • Glycolipids (location and function)
        • Cholesterol's role in the plasma membrane
      • Model organisms in cell research and the origin of eukaryotic genomes
      • Bacterial cell structure and cell wall composition
    • Chapter 2: Molecules of Life
      • Bonds present in starch, glycogen, and cellulose
      • Structure of lipids
      • Role/functions of nucleotides
      • Structure of proteins (primary, secondary, tertiary, etc.)
      • Carrier proteins
      • Active transport, facilitated diffusion, and channel-mediated and passive diffusion (rates)
    • Chapter 10: Protein Processing and Regulation
      • Chaperones/chaperonins/HSPs (heat-shock proteins) and their functions
      • Cystic Fibrosis (detailed information)
      • Protein disulfide isomerase (PDI)/Peptidyl prolyl isomerase (location and functions)
      • Signal sequences (what they are and their functions/roles)
      • Signal peptidase (role/function)
      • Glycosylation, including its purpose
      • Regulation of protein function
      • Allosteric regulation
      • Protein degradation pathway
    • Chapter 11: The Nucleus
      • Nuclear envelope (structure and function)
      • Nuclear lamina (structure)
      • RNA processing (splicing, capping, polyadenylation)
      • Nucleolus (site of ribosomal RNA synthesis)
    • Chapter 12: Protein Sorting and Transport
      • ER structure and functions (rough ER, smooth ER)
      • Translocon (protein-conducting channel)
      • Golgi apparatus structure and function
      • Transport mechanisms (tight junctions, gap junctions, hemidesmosomes)
      • Modifications and sorting of proteins in the Golgi for transport
    • Chapter 13: Mitochondria and Peroxisomes
      • Mitochondrial genome (structure)
      • Peroxisomes (enzymes & functions)
    • Chapter 14: The Cytoskeleton
      • Cytoskeletal elements (actin filaments, microtubules, intermediate filaments, and their roles)
    • Chapter 15: Plasma Membrane
      • Phospholipids (structure/roles)
      • Lipid rafts (composition and signaling role)
      • Transport mechanisms (symport, antiport, uniport)
    • Chapter 16: Cell Signaling
      • Signaling modes (autocrine, paracrine, endocrine)
      • G protein-coupled receptors (GPCRs)
      • Second messengers (cAMP, cGMP, nitric oxide)
      • Peptide hormones (insulin, glucagon)

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    Prepare for your final exam in Cell and Molecular Biology with this comprehensive quiz. Cover key topics including cell structure, molecules of life, and protein processing. Test your understanding of the essential concepts that shape the field of cell biology.

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