Causes of Hyponatraemia Beyond Reduced Plasma Osmolality
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Questions and Answers

What is pseudohyponatraemia?

  • Hyponatraemia due to hyperglycaemia or administration of mannitol
  • An artefactual result due to a reduction in plasma water caused by marked hyperlipidaemia or hyperproteinaemia (correct)
  • Hyponatraemia occurring in association with reduced plasma osmolality
  • Hyponatraemia caused by collection of a blood specimen from a vein close to a site at which fluid is being administered intravenously
  • What is the main cause of hyperosmolar hyponatraemia?

  • Hyperglycaemia (correct)
  • Administration of mannitol
  • Shift of water out of the cells into the ECF in response to osmotic effects
  • Reduced plasma osmolality
  • What can cause artefactual 'hyponatraemia'?

  • Reduced plasma osmolality
  • Collection of a blood specimen from a vein close to a site at which fluid is being administered intravenously (correct)
  • Marked hyperlipidaemia or hyperproteinaemia
  • Hyperglycaemia
  • What characterizes true hyponatraemia?

    <p>Low plasma Na+ occurs in association with reduced plasma osmolality</p> Signup and view all the answers

    What effect can marked hyperlipidaemia or hyperproteinaemia have on sodium concentration measurements?

    <p>'Pseudohyponatraemia', an artefactual result due to a reduction in plasma water</p> Signup and view all the answers

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