Causes of Cardiogenic and Obstructive Shock
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Questions and Answers

What is the main difference between cryoprecipitate and human albumin?

  • Cryoprecipitate contains fibrinogen, factor VIII, and fibronectin, while human albumin contains purified factor VIII and IX concentrates.
  • Cryoprecipitate is stored for up to a year, while human albumin is stored for a shorter duration.
  • Cryoprecipitate is pasteurized at 60°C, while human albumin is frozen at -30°C.
  • Cryoprecipitate has no compatibility requirements, while human albumin does. (correct)
  • In what cases is cryoprecipitate commonly used?

  • To maintain plasma albumin levels in burns.
  • In acute blood volume replacement.
  • When fibrinogen levels are low. (correct)
  • When factor VIII levels are low.
  • What is the process involved in preparing human albumin?

  • It contains fibrinogen, factor VIII, and fibronectin, and is stored for up to a year.
  • It is prepared from large pools of plasma after controlled thawing.
  • It is resuspended in 10-20 ml plasma after freezing to -30°C.
  • It is pasteurized at 60°C for 10 hours after fractionation of large pools of donated plasma. (correct)
  • Which component is common between cryoprecipitate and human albumin?

    <p>Factor VIII</p> Signup and view all the answers

    What is the purpose of resuspending cryoprecipitate in plasma before freezing it again?

    <p>To achieve ABO compatibility.</p> Signup and view all the answers

    Why is cryoprecipitate considered to carry the same basic risk of infection as FFP?

    <p>Because it is concentrated from multiple donor units.</p> Signup and view all the answers

    Which condition may necessitate the use of cryoprecipitate?

    <p>Bleeding associated with uraemia</p> Signup and view all the answers

    Which of the following is NOT a principal category of shock?

    <p>Metabolic</p> Signup and view all the answers

    What is the primary cause of neurogenic shock?

    <p>Spinal cord injury</p> Signup and view all the answers

    Which of the following is NOT a common cause of hypovolaemic shock?

    <p>Septic infection</p> Signup and view all the answers

    What is the primary mechanism by which burns can lead to hypovolaemic shock?

    <p>Both direct fluid loss and fluid sequestration</p> Signup and view all the answers

    Which of the following is a common iatrogenic factor that can contribute to hypovolaemic shock?

    <p>All of the above</p> Signup and view all the answers

    What is the primary mechanism underlying septic shock?

    <p>Vasodilation and decreased vascular resistance</p> Signup and view all the answers

    Which of the following is a common sign of shock?

    <p>All of the above</p> Signup and view all the answers

    What is the primary mechanism underlying anaphylactic shock?

    <p>Vasodilation and increased vascular permeability</p> Signup and view all the answers

    Which of the following is NOT a common treatment for shock?

    <p>Diuretics</p> Signup and view all the answers

    What is the primary mechanism underlying cardiogenic shock?

    <p>Myocardial depression and decreased cardiac output</p> Signup and view all the answers

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