Podcast
Questions and Answers
Which journal published the highest number of articles among the top 50 cited articles?
Which journal published the highest number of articles among the top 50 cited articles?
- European Spine Journal
- British Journal of Neurosurgery
- Spine (correct)
- Journal of Neurosurgery
In which decade were the most articles on cauda equina syndrome published?
In which decade were the most articles on cauda equina syndrome published?
- 1980s
- 2000s (correct)
- 1990s
- 1950s
How many articles were published in the British Medical Journal related to the top 50 cited articles?
How many articles were published in the British Medical Journal related to the top 50 cited articles?
- 2 (correct)
- 3
- 5
- 4
Which article represents the earliest publication related to cauda equina syndrome?
Which article represents the earliest publication related to cauda equina syndrome?
How many articles were published in the Journal of Bone and Joint Surgery?
How many articles were published in the Journal of Bone and Joint Surgery?
What condition can lead to permanent neurological deficits if not diagnosed and addressed promptly?
What condition can lead to permanent neurological deficits if not diagnosed and addressed promptly?
Which journal had the same number of articles published as the European Spine Journal?
Which journal had the same number of articles published as the European Spine Journal?
What was the primary objective of the authors in this article?
What was the primary objective of the authors in this article?
What bibliographic database was used for article selection in the study?
What bibliographic database was used for article selection in the study?
Which of the following journals featured only 2 articles among the top cited articles?
Which of the following journals featured only 2 articles among the top cited articles?
Which article was written most recently in the context of cauda equina syndrome?
Which article was written most recently in the context of cauda equina syndrome?
How many articles matched the search criteria for cauda equina syndrome?
How many articles matched the search criteria for cauda equina syndrome?
In what year did the authors conduct their search for impactful articles on CES?
In what year did the authors conduct their search for impactful articles on CES?
What types of prognoses can lead to cauda equina syndrome?
What types of prognoses can lead to cauda equina syndrome?
What citation range was noted for the top 50 impactful articles on CES?
What citation range was noted for the top 50 impactful articles on CES?
What element was NOT recorded while analyzing the top articles on CES?
What element was NOT recorded while analyzing the top articles on CES?
What is the estimated false positive rate for the clinical diagnosis of cauda equina syndrome?
What is the estimated false positive rate for the clinical diagnosis of cauda equina syndrome?
Which symptom is widely regarded as the most important factor for diagnosing cauda equina syndrome?
Which symptom is widely regarded as the most important factor for diagnosing cauda equina syndrome?
What is the range of timelines for the progression of symptoms related to cauda equina syndrome?
What is the range of timelines for the progression of symptoms related to cauda equina syndrome?
Which of the following conditions has the same number of articles as anesthetic complications in the table?
Which of the following conditions has the same number of articles as anesthetic complications in the table?
Which factor is NOT mentioned as a common presentation for cauda equina syndrome?
Which factor is NOT mentioned as a common presentation for cauda equina syndrome?
What is a significant challenge in diagnosing cauda equina syndrome?
What is a significant challenge in diagnosing cauda equina syndrome?
During which annual meeting was the diagnosis and treatment of cauda equina syndrome discussed?
During which annual meeting was the diagnosis and treatment of cauda equina syndrome discussed?
What is the total number of articles focused on fractures/dislocations as per the table?
What is the total number of articles focused on fractures/dislocations as per the table?
What does the author propose as a potential solution for the complications observed in the patients?
What does the author propose as a potential solution for the complications observed in the patients?
Which publication discusses irreversible conduction block caused by high concentrations of local anesthetics?
Which publication discusses irreversible conduction block caused by high concentrations of local anesthetics?
What was the effect of 5% lidocaine or 0.5% tetracaine on the isolated nerves?
What was the effect of 5% lidocaine or 0.5% tetracaine on the isolated nerves?
What was the focus of the 2000 article by Ahn et al.?
What was the focus of the 2000 article by Ahn et al.?
How many patient outcomes were evaluated in the meta-analysis mentioned?
How many patient outcomes were evaluated in the meta-analysis mentioned?
What characteristic of the nerves exposed to lower concentrations of local anesthetics was observed?
What characteristic of the nerves exposed to lower concentrations of local anesthetics was observed?
What complication was noted in all four patients mentioned in the study?
What complication was noted in all four patients mentioned in the study?
Which local anesthetic concentration was NOT mentioned as causing irreversible conduction block?
Which local anesthetic concentration was NOT mentioned as causing irreversible conduction block?
Which of the following factors can affect the long-term outcome for patients with cauda equina syndrome?
Which of the following factors can affect the long-term outcome for patients with cauda equina syndrome?
What is a common cause of cauda equina syndrome in the context of surgical procedures?
What is a common cause of cauda equina syndrome in the context of surgical procedures?
What is the significance of timing in surgical interventions for cauda equina syndrome?
What is the significance of timing in surgical interventions for cauda equina syndrome?
Which of the following conditions is least likely to cause cauda equina syndrome?
Which of the following conditions is least likely to cause cauda equina syndrome?
What aspect of cauda equina syndrome is directly impacted by anatomical variations in the lumbar spinal canal?
What aspect of cauda equina syndrome is directly impacted by anatomical variations in the lumbar spinal canal?
What kind of treatment is primarily suggested for cauda equina syndrome?
What kind of treatment is primarily suggested for cauda equina syndrome?
Which of the following complications is frequently associated with cauda equina syndrome?
Which of the following complications is frequently associated with cauda equina syndrome?
In the context of cauda equina syndrome, what does a meta-analysis suggest about urinary retention?
In the context of cauda equina syndrome, what does a meta-analysis suggest about urinary retention?
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Study Notes
Cauda Equina Syndrome (CES)
- A rare condition leading to permanent neurological deficits if not diagnosed and treated promptly
- Prognosis varies, including retropulsed fracture fragments, disc herniations, and epidural abscesses
- CES is often caused by compression of sacral and lumbar nerve roots
- The exact symptoms of CES are unclear, but often include:
- Sensory loss
- Bladder dysfunction (often regarded as the most important indicator for diagnosis)
- Back pain
- Weakness
- Symptoms can progress rapidly over days or slowly over months, making diagnosis challenging
Research on CES
- 2096 articles on CES were identified in the Web of Science Core Collection bibliographic database from 1900 to 2021
- The top 50 most cited articles ranged from 43 to 439 citations
- The most common journals for these articles are:
- Spine
- Anesthesiology
- British Journal of Neurosurgery
- European Spine Journal
- Journal of Neurosurgery
- The Journal of Bone and Joint Surgery
- The 2000s was the most active decade for CES publications (20 articles)
- The oldest article is from 1938 and the most recent is from 2014
- The most common topics are:
- Disc Herniations
- Anesthetic Complications
- Timing of Surgical Intervention
- False positive rate for CES is 43%
Key Studies
- Lambert et al. (1991)
- Four patients developed CES, presumably due to a high local anesthetic dose during epidural anesthesia
- Authors suggest a ceiling to local anesthetic dose as a potential solution to this complication
- Wilson (1969)
- Examined the significance of a small lumbar spinal canal and cauda equina compression syndromes due to spondylosis
- Drasner et al. (1992)
- Investigated CES following intended epidural anesthesia
- McCarthy et al. (2007)
- Analyzed factors impacting functional and sphincteric outcome in CES
- DeLong et al. (2008)
- Meta-analyzed observational studies on the timing of surgery in CES with urinary retention
- Orendácová et al. (2001)
- Reviewed the history and current understanding of CES
- Tatter and Cosgrove (1994)
- Reported a case of CES caused by hemorrhage into a lumbar synovial cyst
- Delamarter et al. (1991)
- Studied the neurological recovery following early, late, or immediate decompression in CES
- Qureshi and Sell (2007)
- Evaluated the influence of timing on surgical outcomes in CES treated by surgical decompression
- Ahn et al. (2000)
- Analyzed surgical outcomes of CES secondary to lumbar disc herniation, focusing on clinical outcomes of patients with surgical decompression at varying lengths following the onset of symptoms.
Additional Notes
- The pathophysiology of CES remains unclear
- There is no consensus on the exact symptoms of CES
- The British Association of Spine Surgeons stated that clinical signals for CES are diverse and have no predictive value on patient outcomes
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