Cardiovascular System - The Heart
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Questions and Answers

What is the name of the structure that prevents the heart from overstretching?

  • Pericardial sac
  • Serous pericardium
  • Visceral layer
  • Fibrous pericardium (correct)
  • Which of the following is NOT a surface of the heart?

  • Posterior
  • Lateral (correct)
  • Anterior
  • Inferior
  • Where is the heart located?

  • Left side of the abdominal cavity
  • Center of the thoracic cavity, in the mediastinum (correct)
  • Right side of the thoracic cavity
  • Left side of the pelvic cavity
  • What is the outermost layer of the heart called?

    <p>Epicardium (A)</p> Signup and view all the answers

    Which layer of the pericardium lines the inner part of the fibrous pericardium?

    <p>Parietal layer (B)</p> Signup and view all the answers

    Which of the following statements about the apex of the heart is TRUE?

    <p>The apex moves during ventricular contraction. (B)</p> Signup and view all the answers

    What is the function of the pericardium?

    <p>To protect and support the heart (B)</p> Signup and view all the answers

    What is the name of the inner layer of the serous pericardium that lines the outer surface of the heart?

    <p>Visceral layer (B)</p> Signup and view all the answers

    What is the primary function of the small cardiac vein?

    <p>Drains the right atrium and ventricle (C)</p> Signup and view all the answers

    Which vein drains directly into the coronary sinus?

    <p>Oblique vein of the left atrium (A)</p> Signup and view all the answers

    What is the unique characteristic of cardiac muscle cells that differentiates them from skeletal muscle cells?

    <p>Cardiac muscle cells function as a single unit. (A)</p> Signup and view all the answers

    What feature is responsible for the unique interconnected network of cardiac muscle cells?

    <p>Intercalated discs (D)</p> Signup and view all the answers

    Which aspect of the cardiomyocyte structure is responsible for increasing the surface area of intercellular contact?

    <p>Interdigitating folds (C)</p> Signup and view all the answers

    What is the role of the transverse tubules (T-tubules) in cardiac muscle cells?

    <p>Conduct electrical impulses (A)</p> Signup and view all the answers

    Which of these characteristics is NOT a feature of cardiomyocytes?

    <p>Lack of sarcoplasmic reticulum (B)</p> Signup and view all the answers

    What is the main function of mechanical junctions found in intercalated discs?

    <p>To provide structural support by tightly linking cells (C)</p> Signup and view all the answers

    What pressure must be exceeded for the semilunar valves to open?

    <p>Aortic pressure (B)</p> Signup and view all the answers

    What is the volume of blood that each ventricle ejects during a single heartbeat?

    <p>70 mL (C)</p> Signup and view all the answers

    What occurs immediately after the closure of the semilunar valves?

    <p>Decrease in ventricular pressure (A)</p> Signup and view all the answers

    What is the term for the volume of blood remaining in the ventricles after ejection?

    <p>End-systolic volume (A)</p> Signup and view all the answers

    What represents the initial cause for the closure of the AV valves?

    <p>Rising ventricular pressure (C)</p> Signup and view all the answers

    During which phase does the dicrotic wave occur?

    <p>Isovolumetric relaxation (C)</p> Signup and view all the answers

    How long does atrial systole last in a resting heart at 75 bpm?

    <p>0.4 seconds (C)</p> Signup and view all the answers

    What causes the AV valves to open during ventricular filling?

    <p>Decreased pressure in the ventricles (C)</p> Signup and view all the answers

    What is the primary function of the left semilunar valve?

    <p>To allow oxygenated blood to enter the aorta (D)</p> Signup and view all the answers

    Which structure prevents blood from moving back into the right atrium during ventricular contraction?

    <p>Tricuspid valve (D)</p> Signup and view all the answers

    What occurs during the contraction of the left atrium?

    <p>Blood is pushed from the left atrium into the left ventricle (B)</p> Signup and view all the answers

    What role do the pulmonary arteries play in the circulatory system?

    <p>They carry deoxygenated blood to the lungs (B)</p> Signup and view all the answers

    Where does blood returning from the lungs enter the heart?

    <p>Left atrium (D)</p> Signup and view all the answers

    Which of these best describes systemic circulation?

    <p>Pumps oxygenated blood to the general systemic circulation (A)</p> Signup and view all the answers

    Which valve is responsible for closing to prevent blood from moving back into the left atrium?

    <p>Bicuspid valve (C)</p> Signup and view all the answers

    What happens to CO2 in the lungs during pulmonary circulation?

    <p>It is exchanged for oxygen (D)</p> Signup and view all the answers

    What does cardiac output primarily measure?

    <p>The actual work done by the heart (C)</p> Signup and view all the answers

    Which of the following is considered intrinsic regulation of cardiac output?

    <p>Functional characteristics of the heart (A)</p> Signup and view all the answers

    What is preload in the context of heart function?

    <p>The stretch of the heart before contraction (C)</p> Signup and view all the answers

    According to the Frank-Starling law, what happens when preload increases?

    <p>The strength of contraction increases (D)</p> Signup and view all the answers

    What role do positive inotropic agents play in myocardial contractility?

    <p>They promote calcium inflow to strengthen contractions (B)</p> Signup and view all the answers

    Which of the following factors affects contractility negatively?

    <p>Inhibition of the sympathetic division (A)</p> Signup and view all the answers

    What does afterload refer to in cardiac physiology?

    <p>The pressure that must be exceeded for blood ejection (D)</p> Signup and view all the answers

    What does regulation of stroke volume ensure in the heart?

    <p>Equal volume of blood pump from the left and right ventricles (C)</p> Signup and view all the answers

    What is the primary function of the cardiovascular center in the medulla oblongata?

    <p>To regulate the speed of the heartbeat and blood pressure (A)</p> Signup and view all the answers

    What neurotransmitter is released by sympathetic postganglionic fibers to increase heart rate?

    <p>Norepinephrine (D)</p> Signup and view all the answers

    What effect does the activation of cyclic AMP have on heart muscle cells?

    <p>It increases the permeability of the plasma membrane to calcium ions (B)</p> Signup and view all the answers

    What is the physiological reason for the limitation on maximum heart rate?

    <p>The refractory period of the SA node prevents it from firing faster. (C)</p> Signup and view all the answers

    Why does cardiac output peak at a heart rate of 160 to 180 bpm and then decline?

    <p>The ventricles do not have sufficient time to fill with blood between beats at higher rates. (A)</p> Signup and view all the answers

    What is the primary mechanism by which parasympathetic vagus nerves reduce heart rate?

    <p>They open potassium channels in the nodal cells, causing hyperpolarization. (A)</p> Signup and view all the answers

    What is the effect of a longer diastolic period on stroke volume?

    <p>It increases stroke volume by allowing for more complete ventricular filling. (D)</p> Signup and view all the answers

    Which of the following is NOT a direct effect of the sympathetic nervous system on the heart?

    <p>Increased blood flow to the skeletal muscles (A)</p> Signup and view all the answers

    Flashcards

    Cardiac Output

    The amount of blood the heart pumps per minute, measuring actual work done.

    Intrinsic Regulation

    Heart regulation based on its own functional characteristics, not influenced by external factors.

    Extrinsic Regulation

    Heart regulation controlled by neural and hormonal factors outside the heart.

    Stroke Volume

    The volume of blood pumped by the heart with each contraction.

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    Preload

    The degree of stretch in the heart muscle before contraction, related to end-diastolic volume.

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    Frank-Starling Law

    The principle that greater preload leads to increased force of contraction, equalizing blood output of both ventricles.

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    Contractility

    The forcefulness of the heart's contraction at a given preload, influenced by inotropic agents.

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    Afterload

    The pressure that must be overcome for blood to be ejected from the ventricles.

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    Heart Rate Regulation

    Heart rate changes are crucial for adjusting cardiac output and blood pressure.

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    Medulla Oblongata Role

    Coordinates the nervous system controls for cardiovascular function.

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    Sympathetic Nervous System

    Stimulates heart speed by releasing norepinephrine at adrenergic fibers.

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    Norepinephrine Function

    Binds to beta-adrenergic receptors, increasing heart rate and calcium inflow.

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    Tachycardia

    Increased heart rate, can reach up to 230 bpm due to adrenergic stimulation.

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    Diastole Duration

    The phase of the cardiac cycle when ventricles fill with blood; shortened at high heart rates.

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    Parasympathetic Effects

    Slows heart rate through vagus nerves by releasing acetylcholine.

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    Aortic Semilunar Valve

    The valve that allows oxygenated blood to flow from the left ventricle into the aorta.

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    Deoxygenated Blood

    Blood that is low in oxygen and high in carbon dioxide, returning from the body to the heart.

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    Right Atrium

    Chamber of the heart receiving deoxygenated blood from the body via vena cavae.

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    Tricuspid Valve

    The valve that prevents backflow of blood from the right ventricle into the right atrium.

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    Pulmonary Circulation

    The pathway where deoxygenated blood is transported from the right side of the heart to the lungs.

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    Left Atrium

    Chamber of the heart that receives oxygenated blood from the lungs through pulmonary veins.

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    Bicuspid Valve

    The valve that prevents blood backflow from the left ventricle into the left atrium, also known as the mitral valve.

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    Systemic Circulation

    The pathway where oxygenated blood is pumped from the left side of the heart to the body.

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    Ventricular ejection

    Phase where ventricles pump blood into aorta and pulmonary trunk.

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    AV valves closure

    Closing of atrioventricular valves produces the first heart sound.

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    End-systolic volume (ESV)

    Volume of blood remaining in ventricles after contraction, about 60 mL.

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    Isovolumetric relaxation

    Phase where ventricles relax and pressure decreases, closing semilunar valves.

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    Dicrotic wave

    Secondary rise in aortic pressure caused by blood rebounding against closed valve.

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    Ventricular filling

    Phase where ventricles fill with blood due to low pressure during diastole.

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    Duration of cardiac cycle

    Total time for one complete heart cycle, about 0.8 seconds at 75 bpm.

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    Heart Structure

    A cone-shaped organ about the size of a clenched fist that pumps blood.

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    Mediastinum

    The area in the chest cavity where the heart is located.

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    Apex of the Heart

    The pointed end of the heart that moves during contractions.

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    Base of the Heart

    The uppermost part of the heart, fixed in position due to attachments.

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    Pericardium

    The protective sac surrounding the heart.

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    Fibrous Pericardium

    A tough layer of connective tissue that prevents heart overstretching.

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    Serous Pericardium

    Delicate inner tissue of the pericardium with parietal and visceral layers.

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    Intercostal Space

    The area between the ribs where the apex can be felt during a heartbeat.

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    Small cardiac vein

    Drains blood from the right atrium and ventricle.

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    Posterior vein of the left ventricle

    Drains blood from the lateral wall of the left ventricle.

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    Oblique vein of the left atrium

    Drains the posterior wall of the left atrium into the coronary sinus.

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    Left marginal vein

    Drains blood from the lateral wall of the left ventricle.

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    Anterior cardiac veins

    Collect blood from the front of the right ventricle into the right atrium.

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    Cardiac muscle cells (cardiomyocytes)

    Striated cells that function as a unit and are responsible for heart contractions.

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    Intercalated discs

    Connect cardiac muscle cells with features for strong connections and communication.

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    Mitochondria in cardiomyocytes

    Larger and more numerous than in skeletal muscle, providing energy for contractions.

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    Study Notes

    Cardiovascular System - The Heart

    • The heart is a cone-shaped organ, roughly the size of a clenched fist, located in the mediastinum of the chest cavity.
    • It pumps blood throughout the body's blood vessels.
    • The heart is tilted diagonally, with two-thirds of its mass positioned to the left of the chest's midline.
    • The pointed end of the heart is called the apex, extending forward, downward, and to the left, between the 5th and 6th ribs roughly at the midclavicular line.
    • The broad superior part is called the base, located superiorly, posteriorly, and to the right.
    • The heart's base is not mobile, fixed by its connections to major blood vessels.
    • The apex moves during ventricular contractions, striking the left chest wall near the 5th intercostal space.

    Structure and Function of the Pericardium

    • The heart is enclosed within a protective sac called the pericardium.
    • Fibrous pericardium is a tough, fibrous outer layer preventing excessive stretching of the heart.
    • Serous pericardium is a thinner inner lining with two layers:
      • Parietal layer: lines the inner surface of the fibrous pericardium.
      • Visceral layer: covers the outer surface of the heart.
    • The space between the parietal and visceral layers is filled with serous pericardial fluid, reducing friction as the heart moves.

    Chambers and Valves of the Heart

    • The heart has four chambers: two atria (upper) and two ventricles (lower).
    • The atria collect blood returning to the heart.
    • The ventricles pump blood out of the heart.
    • A muscular septum (wall) divides the heart into left and right halves.
    • The right and left atria are separated by the interatrial septum.
    • The right and left ventricles are separated by the interventricular septum.
    • Atrioventricular (AV) valves (tricuspid and mitral valves) regulate blood flow between atria and ventricles.
    • Semilunar valves (pulmonary and aortic valves) control flow from the heart to the pulmonary trunk (to the lungs) and the aorta (to the body), respectively.

    Heart Valves

    • The valves in the heart ensure one-way blood flow through the heart.
    • Right and Left Atrioventricular valves (tricuspid and mitral valves) prevent backflow from the ventricles into the atria during ventricular contraction.
    • Semilunar valves (pulmonary and aortic valves) prevent blood from flowing back into the ventricles from the pulmonary artery and aorta, respectively, during ventricular relaxation.

    Cardiac Muscle Tissue

    • Cardiac muscle cells (cardiomyocytes) are striated, branched, and have a single central nucleus.
    • They connect to each other at intercalated discs, facilitating rapid transmission of electrical signals.
    • Cardiac muscle has a unique autorhythmic property, meaning specialized cells in the conduction system spontaneously generate action potentials which drive the heart's rhythmic contractions.

    Cardiac Conduction System

    • The Sinoatrial (SA) node, located in the right atrium, is the heart's natural pacemaker, initiating rhythmic contractions.
    • Action potentials spread from the SA node through the atria and to the Atrioventricular (AV) node.
    • The AV node slows the impulse conduction before it enters the ventricles, allowing the atria to fully empty into the ventricles.
    • Action potentials then spread through the bundle branches and Purkinje fibers, causing the ventricles to contract.

    Cardiac Cycle

    • The cardiac cycle is the sequence of events in one complete heartbeat, including contraction and relaxation of the atria and ventricles.
    • Systole refers to the period of ventricular contraction, and diastole refers to the period of ventricular relaxation.
    • Various phases of the cycle include the ventricular filling, isovolumetric contraction, ventricular ejection, and isovolumetric relaxation.

    Regulation of the Heart

    • Intrinsic regulation involves the heart's inherent properties, such as the Frank-Starling mechanism, which adjusts stroke volume to the amount of blood returning to the heart.
    • Extrinsic regulation occurs due to neural control (sympathetic and parasympathetic) and hormonal influences, notably epinephrine and norepinephrine.

    Electrocardiogram (ECG)

    • An ECG measures the electrical activity of the heart.
    • Characteristic waves (P, QRS, T) on an ECG correspond to different phases of the cardiac cycle.

    Systemic, Pulmonary, and Coronary Circulation

    • Systemic circulation involves the left side of the heart, delivering oxygenated blood to the body and returning deoxygenated blood to the right side of the heart.
    • Pulmonary circulation involves the right side of the heart, carrying deoxygenated blood to the lungs for oxygenation and returning oxygenated blood to the left side of the heart.
    • Coronary circulation provides blood supply to the heart muscle itself, branching off the aorta.

    Heart Disorders

    • Coronary artery disease involves narrowing or blockage of coronary arteries, reducing blood supply to the heart muscle, leading to angina pectoris or myocardial infarction.
    • Arrhythmias are abnormal heart rhythms.
    • Congenital heart defects are structural problems present at birth.

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    Description

    Explore the structure and function of the heart, a vital organ in the cardiovascular system. Learn about its anatomy, including the apex and base, as well as the protective pericardium that surrounds it. This quiz will test your knowledge of the heart's role in pumping blood throughout the body.

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