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Questions and Answers
What is the name of the structure that prevents the heart from overstretching?
What is the name of the structure that prevents the heart from overstretching?
Which of the following is NOT a surface of the heart?
Which of the following is NOT a surface of the heart?
Where is the heart located?
Where is the heart located?
What is the outermost layer of the heart called?
What is the outermost layer of the heart called?
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Which layer of the pericardium lines the inner part of the fibrous pericardium?
Which layer of the pericardium lines the inner part of the fibrous pericardium?
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Which of the following statements about the apex of the heart is TRUE?
Which of the following statements about the apex of the heart is TRUE?
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What is the function of the pericardium?
What is the function of the pericardium?
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What is the name of the inner layer of the serous pericardium that lines the outer surface of the heart?
What is the name of the inner layer of the serous pericardium that lines the outer surface of the heart?
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What is the primary function of the small cardiac vein?
What is the primary function of the small cardiac vein?
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Which vein drains directly into the coronary sinus?
Which vein drains directly into the coronary sinus?
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What is the unique characteristic of cardiac muscle cells that differentiates them from skeletal muscle cells?
What is the unique characteristic of cardiac muscle cells that differentiates them from skeletal muscle cells?
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What feature is responsible for the unique interconnected network of cardiac muscle cells?
What feature is responsible for the unique interconnected network of cardiac muscle cells?
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Which aspect of the cardiomyocyte structure is responsible for increasing the surface area of intercellular contact?
Which aspect of the cardiomyocyte structure is responsible for increasing the surface area of intercellular contact?
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What is the role of the transverse tubules (T-tubules) in cardiac muscle cells?
What is the role of the transverse tubules (T-tubules) in cardiac muscle cells?
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Which of these characteristics is NOT a feature of cardiomyocytes?
Which of these characteristics is NOT a feature of cardiomyocytes?
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What is the main function of mechanical junctions found in intercalated discs?
What is the main function of mechanical junctions found in intercalated discs?
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What pressure must be exceeded for the semilunar valves to open?
What pressure must be exceeded for the semilunar valves to open?
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What is the volume of blood that each ventricle ejects during a single heartbeat?
What is the volume of blood that each ventricle ejects during a single heartbeat?
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What occurs immediately after the closure of the semilunar valves?
What occurs immediately after the closure of the semilunar valves?
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What is the term for the volume of blood remaining in the ventricles after ejection?
What is the term for the volume of blood remaining in the ventricles after ejection?
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What represents the initial cause for the closure of the AV valves?
What represents the initial cause for the closure of the AV valves?
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During which phase does the dicrotic wave occur?
During which phase does the dicrotic wave occur?
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How long does atrial systole last in a resting heart at 75 bpm?
How long does atrial systole last in a resting heart at 75 bpm?
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What causes the AV valves to open during ventricular filling?
What causes the AV valves to open during ventricular filling?
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What is the primary function of the left semilunar valve?
What is the primary function of the left semilunar valve?
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Which structure prevents blood from moving back into the right atrium during ventricular contraction?
Which structure prevents blood from moving back into the right atrium during ventricular contraction?
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What occurs during the contraction of the left atrium?
What occurs during the contraction of the left atrium?
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What role do the pulmonary arteries play in the circulatory system?
What role do the pulmonary arteries play in the circulatory system?
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Where does blood returning from the lungs enter the heart?
Where does blood returning from the lungs enter the heart?
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Which of these best describes systemic circulation?
Which of these best describes systemic circulation?
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Which valve is responsible for closing to prevent blood from moving back into the left atrium?
Which valve is responsible for closing to prevent blood from moving back into the left atrium?
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What happens to CO2 in the lungs during pulmonary circulation?
What happens to CO2 in the lungs during pulmonary circulation?
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What does cardiac output primarily measure?
What does cardiac output primarily measure?
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Which of the following is considered intrinsic regulation of cardiac output?
Which of the following is considered intrinsic regulation of cardiac output?
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What is preload in the context of heart function?
What is preload in the context of heart function?
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According to the Frank-Starling law, what happens when preload increases?
According to the Frank-Starling law, what happens when preload increases?
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What role do positive inotropic agents play in myocardial contractility?
What role do positive inotropic agents play in myocardial contractility?
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Which of the following factors affects contractility negatively?
Which of the following factors affects contractility negatively?
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What does afterload refer to in cardiac physiology?
What does afterload refer to in cardiac physiology?
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What does regulation of stroke volume ensure in the heart?
What does regulation of stroke volume ensure in the heart?
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What is the primary function of the cardiovascular center in the medulla oblongata?
What is the primary function of the cardiovascular center in the medulla oblongata?
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What neurotransmitter is released by sympathetic postganglionic fibers to increase heart rate?
What neurotransmitter is released by sympathetic postganglionic fibers to increase heart rate?
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What effect does the activation of cyclic AMP have on heart muscle cells?
What effect does the activation of cyclic AMP have on heart muscle cells?
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What is the physiological reason for the limitation on maximum heart rate?
What is the physiological reason for the limitation on maximum heart rate?
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Why does cardiac output peak at a heart rate of 160 to 180 bpm and then decline?
Why does cardiac output peak at a heart rate of 160 to 180 bpm and then decline?
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What is the primary mechanism by which parasympathetic vagus nerves reduce heart rate?
What is the primary mechanism by which parasympathetic vagus nerves reduce heart rate?
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What is the effect of a longer diastolic period on stroke volume?
What is the effect of a longer diastolic period on stroke volume?
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Which of the following is NOT a direct effect of the sympathetic nervous system on the heart?
Which of the following is NOT a direct effect of the sympathetic nervous system on the heart?
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Flashcards
Cardiac Output
Cardiac Output
The amount of blood the heart pumps per minute, measuring actual work done.
Intrinsic Regulation
Intrinsic Regulation
Heart regulation based on its own functional characteristics, not influenced by external factors.
Extrinsic Regulation
Extrinsic Regulation
Heart regulation controlled by neural and hormonal factors outside the heart.
Stroke Volume
Stroke Volume
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Preload
Preload
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Frank-Starling Law
Frank-Starling Law
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Contractility
Contractility
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Afterload
Afterload
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Heart Rate Regulation
Heart Rate Regulation
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Medulla Oblongata Role
Medulla Oblongata Role
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Sympathetic Nervous System
Sympathetic Nervous System
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Norepinephrine Function
Norepinephrine Function
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Tachycardia
Tachycardia
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Diastole Duration
Diastole Duration
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Parasympathetic Effects
Parasympathetic Effects
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Aortic Semilunar Valve
Aortic Semilunar Valve
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Deoxygenated Blood
Deoxygenated Blood
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Right Atrium
Right Atrium
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Tricuspid Valve
Tricuspid Valve
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Pulmonary Circulation
Pulmonary Circulation
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Left Atrium
Left Atrium
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Bicuspid Valve
Bicuspid Valve
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Systemic Circulation
Systemic Circulation
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Ventricular ejection
Ventricular ejection
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AV valves closure
AV valves closure
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End-systolic volume (ESV)
End-systolic volume (ESV)
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Isovolumetric relaxation
Isovolumetric relaxation
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Dicrotic wave
Dicrotic wave
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Ventricular filling
Ventricular filling
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Duration of cardiac cycle
Duration of cardiac cycle
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Heart Structure
Heart Structure
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Mediastinum
Mediastinum
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Apex of the Heart
Apex of the Heart
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Base of the Heart
Base of the Heart
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Pericardium
Pericardium
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Fibrous Pericardium
Fibrous Pericardium
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Serous Pericardium
Serous Pericardium
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Intercostal Space
Intercostal Space
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Small cardiac vein
Small cardiac vein
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Posterior vein of the left ventricle
Posterior vein of the left ventricle
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Oblique vein of the left atrium
Oblique vein of the left atrium
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Left marginal vein
Left marginal vein
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Anterior cardiac veins
Anterior cardiac veins
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Cardiac muscle cells (cardiomyocytes)
Cardiac muscle cells (cardiomyocytes)
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Intercalated discs
Intercalated discs
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Mitochondria in cardiomyocytes
Mitochondria in cardiomyocytes
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Study Notes
Cardiovascular System - The Heart
- The heart is a cone-shaped organ, roughly the size of a clenched fist, located in the mediastinum of the chest cavity.
- It pumps blood throughout the body's blood vessels.
- The heart is tilted diagonally, with two-thirds of its mass positioned to the left of the chest's midline.
- The pointed end of the heart is called the apex, extending forward, downward, and to the left, between the 5th and 6th ribs roughly at the midclavicular line.
- The broad superior part is called the base, located superiorly, posteriorly, and to the right.
- The heart's base is not mobile, fixed by its connections to major blood vessels.
- The apex moves during ventricular contractions, striking the left chest wall near the 5th intercostal space.
Structure and Function of the Pericardium
- The heart is enclosed within a protective sac called the pericardium.
- Fibrous pericardium is a tough, fibrous outer layer preventing excessive stretching of the heart.
- Serous pericardium is a thinner inner lining with two layers:
- Parietal layer: lines the inner surface of the fibrous pericardium.
- Visceral layer: covers the outer surface of the heart.
- The space between the parietal and visceral layers is filled with serous pericardial fluid, reducing friction as the heart moves.
Chambers and Valves of the Heart
- The heart has four chambers: two atria (upper) and two ventricles (lower).
- The atria collect blood returning to the heart.
- The ventricles pump blood out of the heart.
- A muscular septum (wall) divides the heart into left and right halves.
- The right and left atria are separated by the interatrial septum.
- The right and left ventricles are separated by the interventricular septum.
- Atrioventricular (AV) valves (tricuspid and mitral valves) regulate blood flow between atria and ventricles.
- Semilunar valves (pulmonary and aortic valves) control flow from the heart to the pulmonary trunk (to the lungs) and the aorta (to the body), respectively.
Heart Valves
- The valves in the heart ensure one-way blood flow through the heart.
- Right and Left Atrioventricular valves (tricuspid and mitral valves) prevent backflow from the ventricles into the atria during ventricular contraction.
- Semilunar valves (pulmonary and aortic valves) prevent blood from flowing back into the ventricles from the pulmonary artery and aorta, respectively, during ventricular relaxation.
Cardiac Muscle Tissue
- Cardiac muscle cells (cardiomyocytes) are striated, branched, and have a single central nucleus.
- They connect to each other at intercalated discs, facilitating rapid transmission of electrical signals.
- Cardiac muscle has a unique autorhythmic property, meaning specialized cells in the conduction system spontaneously generate action potentials which drive the heart's rhythmic contractions.
Cardiac Conduction System
- The Sinoatrial (SA) node, located in the right atrium, is the heart's natural pacemaker, initiating rhythmic contractions.
- Action potentials spread from the SA node through the atria and to the Atrioventricular (AV) node.
- The AV node slows the impulse conduction before it enters the ventricles, allowing the atria to fully empty into the ventricles.
- Action potentials then spread through the bundle branches and Purkinje fibers, causing the ventricles to contract.
Cardiac Cycle
- The cardiac cycle is the sequence of events in one complete heartbeat, including contraction and relaxation of the atria and ventricles.
- Systole refers to the period of ventricular contraction, and diastole refers to the period of ventricular relaxation.
- Various phases of the cycle include the ventricular filling, isovolumetric contraction, ventricular ejection, and isovolumetric relaxation.
Regulation of the Heart
- Intrinsic regulation involves the heart's inherent properties, such as the Frank-Starling mechanism, which adjusts stroke volume to the amount of blood returning to the heart.
- Extrinsic regulation occurs due to neural control (sympathetic and parasympathetic) and hormonal influences, notably epinephrine and norepinephrine.
Electrocardiogram (ECG)
- An ECG measures the electrical activity of the heart.
- Characteristic waves (P, QRS, T) on an ECG correspond to different phases of the cardiac cycle.
Systemic, Pulmonary, and Coronary Circulation
- Systemic circulation involves the left side of the heart, delivering oxygenated blood to the body and returning deoxygenated blood to the right side of the heart.
- Pulmonary circulation involves the right side of the heart, carrying deoxygenated blood to the lungs for oxygenation and returning oxygenated blood to the left side of the heart.
- Coronary circulation provides blood supply to the heart muscle itself, branching off the aorta.
Heart Disorders
- Coronary artery disease involves narrowing or blockage of coronary arteries, reducing blood supply to the heart muscle, leading to angina pectoris or myocardial infarction.
- Arrhythmias are abnormal heart rhythms.
- Congenital heart defects are structural problems present at birth.
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Description
Explore the structure and function of the heart, a vital organ in the cardiovascular system. Learn about its anatomy, including the apex and base, as well as the protective pericardium that surrounds it. This quiz will test your knowledge of the heart's role in pumping blood throughout the body.