Cardiovascular System Quiz
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Questions and Answers

What is the role of the pectinate muscles in the atria?

  • They facilitate blood flow from the atria to the ventricles.
  • They are involved in the conduction system of the heart.
  • They form the valve structures of the heart.
  • They provide muscular support to the atrial walls. (correct)

Which structure is primarily responsible for attaching the septal cusps of the AV valves to the ventricle walls?

  • Trabeculae carnae
  • Fossa ovalis
  • Papillary muscles
  • Chorae tendinae (correct)

What is the conus arteriosis?

  • A conical prolongation of the right ventricle. (correct)
  • A depression in the interatrial septum.
  • A muscular ridge in the left atrium.
  • An opening for the vena cava.

What does the fossa ovalis represent in the heart?

<p>A depression on the interatrial septum. (B)</p> Signup and view all the answers

Which of the following is NOT a feature of the right ventricle?

<p>A.V. orifice (A)</p> Signup and view all the answers

What does stroke volume (SV) refer to?

<p>The volume of blood pumped from one ventricle during each contraction (C)</p> Signup and view all the answers

How is cardiac output (CO) calculated?

<p>CO = stroke volume x heart rate (B)</p> Signup and view all the answers

What role does the parasympathetic nervous system play in heart rate regulation?

<p>It decreases the intrinsic rate of the SA node at rest (C)</p> Signup and view all the answers

Which component is considered part of the cardiac muscle structure?

<p>Striated, short, fat, branched, and interconnected cells (A)</p> Signup and view all the answers

What effect do thyroid hormones have on heart rate?

<p>They facilitate a slow and sustained increase in heart rate (C)</p> Signup and view all the answers

What is the significance of gap junctions in cardiac muscle cells?

<p>They allow ions to pass between cells, enabling electrical conduction (C)</p> Signup and view all the answers

What prevents tetanic contractions in cardiac myocytes?

<p>The longer absolute refractory period (A)</p> Signup and view all the answers

Which factor does NOT typically increase cardiac output (CO)?

<p>Decreased end diastolic volume (A)</p> Signup and view all the answers

What happens to the AV valves during late systole?

<p>They close due to increasing ventricular pressure. (A)</p> Signup and view all the answers

During early diastole, what occurs in the ventricles?

<p>Ventricles experience brief repolarization. (A)</p> Signup and view all the answers

What characterizes Mobitz II type of heart block?

<p>Non-conducting P waves without PR interval elongation. (C)</p> Signup and view all the answers

What happens to atrial pressure during mid-late diastole?

<p>It exceeds ventricular pressure. (A)</p> Signup and view all the answers

What does the Frank-Starling Law state?

<p>Stroke volume increases with an increase in blood filling volume. (A)</p> Signup and view all the answers

During which phase of the cardiac cycle do the aortic and pulmonary valves close?

<p>Early diastole. (A)</p> Signup and view all the answers

When does the SA node fire during the cardiac cycle?

<p>At the end of diastole. (C)</p> Signup and view all the answers

What is the consequence of pressure rising in the ventricles during early systole?

<p>The AV valves close. (D)</p> Signup and view all the answers

What is the primary mode of transmission for hantavirus pulmonary syndrome?

<p>Spread via rodents (D)</p> Signup and view all the answers

Which of the following symptoms is NOT commonly associated with hantavirus pulmonary syndrome?

<p>Severe abdominal pain (C)</p> Signup and view all the answers

What is the source of the left anterior descending coronary artery?

<p>Left coronary artery (B)</p> Signup and view all the answers

Which bacteria is most commonly associated with infective endocarditis in a patient with a ventricular septal defect?

<p>Streptococcus viridans (C)</p> Signup and view all the answers

Which of the following characterizes the difference between cardiac and skeletal muscle contraction?

<p>Cardiac muscle contracts more slowly than skeletal muscle (C)</p> Signup and view all the answers

Which of the following best describes valvular dysfunctions?

<p>Both diastolic and systolic dysfunctions can affect heart function (D)</p> Signup and view all the answers

What is the significance of the aortic sinus in relation to coronary circulation?

<p>It is a dilation above the aortic valve that aids in coronary artery perfusion (C)</p> Signup and view all the answers

Which term refers to the major branches off the aorta important for understanding cardiac anatomy?

<p>Major branches of the aorta (A)</p> Signup and view all the answers

Which artery is responsible for supplying the right atrium and ventricle?

<p>Right Coronary Artery (RCA) (D)</p> Signup and view all the answers

From which part of the aorta does the Left Coronary Artery (LCA) originate?

<p>Left aortic sinus (A)</p> Signup and view all the answers

What is a branch of the Right Coronary Artery (RCA)?

<p>SA nodal artery (A)</p> Signup and view all the answers

Which of the following supplies the left atrium?

<p>LCA (D)</p> Signup and view all the answers

Which arteries provide anastomoses between the RCA and LCA?

<p>Posterior interventricular branch and anterior interventricular branch (A)</p> Signup and view all the answers

What does the Left Coronary Artery (LCA) primarily supply?

<p>Most of the left ventricle (D)</p> Signup and view all the answers

Which artery runs along the AV groove?

<p>Right Coronary Artery (RCA) (B)</p> Signup and view all the answers

Which artery supplies the AV node?

<p>SA nodal artery (C)</p> Signup and view all the answers

What is the primary unknown function of lipoprotein (A)?

<p>It does not have a known function (B)</p> Signup and view all the answers

Which of the following conditions is not classified under hypertensive heart diseases?

<p>Vascular neoplasms (C)</p> Signup and view all the answers

What characterizes pulmonary hypertension?

<p>Average pressure &gt;25 mm Hg in pulmonary vessels (D)</p> Signup and view all the answers

Which group of pulmonary hypertension is associated with left heart disease?

<p>Group II (C)</p> Signup and view all the answers

What is a potential consequence of systemic hypertension?

<p>Chronic renal failure (C)</p> Signup and view all the answers

What measurement indicates systemic hypertension?

<p>Elevated either systolic or diastolic blood pressure on three separate occasions (C)</p> Signup and view all the answers

In pulmonary hypertension, what symptom is aggravated by exertion?

<p>Dyspnea (D)</p> Signup and view all the answers

Which of the following can contribute to elevated systemic blood pressure?

<p>Chronic inflammation (C)</p> Signup and view all the answers

Which type of pulmonary hypertension is characterized as idiopathic or familial?

<p>Group I (B)</p> Signup and view all the answers

What effect does low potassium intake have in relation to systemic hypertension?

<p>Contributes to elevated blood pressure (A)</p> Signup and view all the answers

Flashcards

Fossa ovalis

A depression on the interatrial septum, a remnant of the foramen ovale.

Pectinate muscles

Muscular ridges found in the atria, particularly prominent in the right atrium.

Trabeculae carnae

Muscular elevations or ridges that project into the lumen(inner space) of the ventricles.

Papillary muscles

Muscular projections within the ventricles that attach to the chordae tendinae (tendinous cords) of the AV valves.

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Conus arteriosus

A cone-shaped region where the pulmonary trunk emerges from the right ventricle.

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What do coronary arteries supply?

Coronary arteries supply the outer layer (epicardium) and the middle layer (myocardium) of the heart.

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Where do the LCA and RCA originate?

The Left Coronary Artery (LCA) originates from the left aortic sinus, while the Right Coronary Artery (RCA) originates from the right aortic sinus.

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What is the location of the LCA?

The Left Coronary Artery (LCA) runs along the coronary groove.

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What is the location of the RCA?

The Right Coronary Artery (RCA) runs along the AV groove.

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What are the branches of the LCA?

The Left Coronary Artery (LCA) branches into the SA nodal artery, the anterior interventricular branch, the circumflex branch, and the left marginal branch.

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What are the branches of the RCA?

The Right Coronary Artery (RCA) branches into the SA nodal artery, the right marginal branch, the AV nodal branch, and the posterior interventricular branch.

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What are the anastomoses of the LCA?

The LCA anastomoses with the anterior interventricular branches of the RCA and the circumflex artery.

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What does the RCA supply?

The RCA supplies the SA and AV nodes, the right atrium, the majority of the right ventricle, and a portion of the left ventricle and the AV septum.

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Stroke Volume (SV)

The amount of blood pumped out of the left ventricle with each heartbeat.

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Cardiac Output (CO)

The total amount of blood pumped by the heart per minute.

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What factors influence Cardiac Output?

Cardiac Output is determined by two main factors: Stroke Volume (SV) and Heart Rate (HR). CO = SV x HR.

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How does the nervous system affect heart rate?

The parasympathetic nervous system slows down the heart rate (rest and digest), while the sympathetic nervous system speeds it up (fight or flight).

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How do thyroid hormones impact heart rate?

Thyroid hormones increase heart rate over a longer period of time, and they enhance the effects of adrenaline.

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What are intercalated discs?

Intercalated discs are specialized junctions that connect cardiac muscle cells, allowing them to act as a single unit.

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How do gap junctions in cardiac muscle work?

Gap junctions allow ions to flow freely between cardiac muscle cells, enabling synchronized contractions.

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How do cardiac muscle action potentials differ from skeletal muscle action potentials?

Cardiac action potentials are much longer than skeletal muscle action potentials, and they have a plateau phase caused by calcium influx. They are also resistant to tetanic contractions.

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Mid-Late Diastole

The phase where the ventricles passively fill with blood. The AV valves are open, while the aortic and pulmonary valves are closed. Atrial pressure increases, and the SA node fires at the end, causing atrial contraction.

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Early Systole

The beginning of ventricular contraction. Pressure increases, causing the AV valves to close. The aortic and pulmonary valves remain closed, and ventricular pressure continues to rise.

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Late Systole

The peak of ventricular contraction. The aortic and pulmonary valves open, allowing blood to flow out to the aorta and pulmonary trunk. The remaining blood in the ventricle is called the end-systolic volume.

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Early Diastole

A brief phase of ventricular relaxation. Pressure drops rapidly, the aortic and pulmonary valves close, and the AV valves open because atrial pressure exceeds ventricular pressure.

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Primary Heart Block

A heart condition characterized by a prolonged PR interval on an EKG.

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Mobitz 1 Heart Block

Characterized by progressive lengthening of the PR interval until two atrial depolarizations occur before a ventricular complex.

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Mobitz II Heart Block

Non-conducting P waves with no prolongation of the PR interval. It is more likely to progress to complete heart block.

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Complete Heart Block

Complete blockage of the electrical signal between the atria and ventricles, leading to no QRS wave (Bundle branch block) on an EKG.

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Hantavirus Pulmonary Syndrome (HPS)

A severe respiratory illness caused by infection with hantaviruses, spread through contact with infected rodents.

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HPS Symptoms

High fever, shortness of breath, cough, diarrhea, fatigue, low platelet count, and potential kidney failure.

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Left Anterior Descending (LAD) Coronary Artery

One of the two major branches of the left coronary artery, supplying blood to the front and bottom of the left ventricle.

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Ventricular Septal Defect (VSD)

A hole in the wall separating the left and right ventricles, allowing blood to flow abnormally.

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Infective Endocarditis

An infection of the inner lining of the heart, usually affecting heart valves, commonly caused by bacteria.

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Septic Emboli

Blood clots that travel from the heart to other parts of the body, carrying bacteria and causing infection.

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Streptococcus Viridans

A type of bacteria commonly associated with infective endocarditis in patients with congenital heart conditions like VSD.

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Staphylococcus Aureus

A type of bacteria that can cause infective endocarditis but more often associated with infections elsewhere in the body.

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Lipoprotein (a)

A lipoprotein complex consisting of LDL bound to apo(a). Its function is not fully understood.

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Pulmonary Hypertension

Increased blood pressure in the pulmonary arteries, veins, or capillaries, typically exceeding 25 mmHg. It's often caused by increased resistance in the pulmonary vascular system.

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Systemic Hypertension

Elevated blood pressure in the systemic circulation, typically defined as a systolic pressure of at least 140 mmHg or a diastolic pressure of at least 90 mmHg.

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What are the major complications of systemic hypertension?

Chronic renal failure, retinopathy, aneurysm ruptures, and congestive heart failure.

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What are the potential causes of systemic hypertension?

Excess salt intake with low potassium, chronic inflammation, low magnesium, chronic stress or anxiety, insulin resistance, renal hormone imbalance, obesity, and arteriosclerosis.

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Group 1 Pulmonary Hypertension

Pulmonary arterial hypertension (PAH) that is idiopathic, familial, or associated with systemic diseases like scleroderma or HIV infection.

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Group II Pulmonary Hypertension

Pulmonary hypertension associated with left heart disease, such as atrial or ventricular dysfunction, or valvular disease like mitral stenosis.

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Group III Pulmonary Hypertension

Pulmonary hypertension associated with lung diseases or hypoxemia, such as COPD, interstitial lung disease, or sleep apnea.

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What are the key symptoms of pulmonary hypertension?

Dyspnea, fainting, dizziness, dry cough, angina (worse with exertion), peripheral edema, and orthopnea (difficulty breathing when lying flat).

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What are the characteristic features of Group 1 Pulmonary Hypertension?

Idiopathic, familial, or associated with systemic diseases. It's usually characterized by a significant occlusion of the pulmonary arterial tree (>30-50%).

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Study Notes

Cardiovascular System

  •  This section covers the cardiovascular system, including its embryology, anatomy, physiology, biochemistry, and pathology.
  •  A sample case study regarding hypercholesteremia and its role in atherosclerotic plaque formation is included.
  •  The key regulating enzyme in cholesterol synthesis is HMG-CoA reductase.
  •  A second sample case study discusses a 4-week-old male patient with a ventricular septal defect.
  •  Endocardial cushions are crucial for the proper formation of the heart's septa.
  •  Fetal circulation involves the placenta, umbilical vein, ductus venosus, ductus arteriosus, and foramen ovale.
  •  These structures facilitate the transfer of oxygenated blood from the placenta to the developing fetus.
  •  Cardiac muscle is a striated muscle and is composed of myosin (thick) and actin (thin) filaments.
  •  Cardiac muscle cells are branched and organized into sarcomeres.
  •  Intercalated discs and gap junctions enable rapid depolarization signal propagation.
  •  A description of the three layers of blood vessel walls (Intima, Media, and Adventitia) is included.
  •  Capillaries do not have a media or adventitia layer.
  •  Different types of blood vessels (arteries, arterioles, capillaries, venules, and veins) and their functions are detailed.
  •  The structure and function of cardiac valves (mitral, tricuspid, and semilunar) and their corresponding sounds are explained.
  •  Vascular dysfunction is defined as a malfunctioning blood vessels with examples like regurgitation, stenosis, and other similar conditions.
  •  A detailed diagram of the heart and its anatomy is provided, as well as important blood flows associated with the heart.
  •  Cardiac muscle layers (endocardium, myocardium, and epicardium) and their contributions are detailed.
  •  Different parts of the heart (right atrium, left atrium, right ventricle, and left ventricle) and their functions are elaborated.
  •  The cardiovascular system, including its structure, function, related factors (pressure differences and resistances), and various conditions are described in the later parts of the notes.

Cardiovascular Disease

  •  A discussion of various cardiovascular diseases with examples like hypertensive heart diseases (pulmonary and systemic hypertension), Congestive heart failure with its classifications (left and right-sided), Ischemic heart disease (angina pectoris, chronic ischemic heart disease), and myocardial infarction (MI).
  •  Specific causes and symptoms of each condition are included.
  •  Specific pathologies related to the heart and its structure (e.g., valvular disease), congenital conditions (e.g., bicuspid aortic valve, patent ductus arteriosus and septal defects), and hemodynamic conditions (e.g., embolism, hemorrhage, and infarction), are noted in the discussion of the cardiovascular system.
  •  Detailed descriptions of the roles of different organs, valves, and other anatomical components of the heart are provided to understand how various diseases impact the cardiovascular system.

Lipids

  •  Fatty acids are covered as building blocks of lipids.
  •  The length of the carbon chain and number of double bonds in the tails are used to determine the degree of saturation for fatty acids
  •  Types of fatty acids (saturated, monounsaturated, and polyunsaturated) and examples are described.
  •  Essential fatty acids (EFAs) like linoleic and alpha-linolenic acid, and their roles as precursors to important molecules (eicosanoids) are detailed.
  •  Short-chain fatty acids (SCFA), especially butyrate, in the context of their roles in various aspects of bodily functions are discussed.
  •  Fatty Acid Oxidation, Synthesis, and the importance of different enzymes and intermediate molecules are covered.
  •  A discussion of different Lipoproteins, their classifications and functions is included in these notes.

Cholesterol and Steroid Synthesis

  •  Cholesterol synthesis, in the liver and intestines, as well as its role in regulating membrane fluidity.
  •  The rate-limiting enzyme HMG-CoA reductase involved in Cholesterol synthesis.
  •  Important regulators and factors affecting cholesterol synthesis.
  •  Steroid synthesis, as a process of producing steroid hormones, and includes the specific hormones produced, as well as the precursors, in these notes.
  •  The role of cholesterol as a precursor to various other important biological molecules is included.
  •  The role of lipoproteins in transporting cholesterol and other lipids throughout the body is emphasized.

Other Notes

  •  Specific details on the various pathologies discussed are presented.
  •  Information on the types of diseases discussed and their importance in the cardiovascular system is described.

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Test your knowledge on the cardiovascular system with questions covering heart anatomy, function, and physiology. This quiz delves into topics such as cardiac muscle structure, heart rate regulation, and the roles of various cardiac components. Ideal for students of human biology or any enthusiast wanting to enhance their understanding of the heart.

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