Cardiovascular System Quiz - Anatomy and Physiology
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Questions and Answers

Which of the following factors directly influences cardiac output?

  • Blood Pressure
  • Heart Rate
  • Stroke Volume
  • All of the Above (correct)
  • Which of the following hormones increases contractility?

  • Epinephrine (correct)
  • Aldosterone
  • Cortisol
  • Insulin
  • What is the primary role of the parasympathetic nervous system in regulating heart rate?

  • Increase heart rate
  • Decrease heart rate (correct)
  • Maintain a constant heart rate
  • Increase contractility
  • Which of the following factors contributes to increased stroke volume?

    <p>Both A and B (B)</p> Signup and view all the answers

    What is the role of the cardioinhibitory center (CIC) in regulating heart rate?

    <p>Inhibits heart rate (D)</p> Signup and view all the answers

    Which of the following is NOT a factor that decreases contractility?

    <p>Increased sympathetic activity (C)</p> Signup and view all the answers

    What is the relationship between stroke volume and cardiac output?

    <p>Stroke volume is a component of cardiac output (A)</p> Signup and view all the answers

    Which of the following factors does NOT directly affect stroke volume?

    <p>Heart rate (A)</p> Signup and view all the answers

    Which of the following structures is responsible for anchoring the AV valves to the papillary muscles?

    <p>Chordae tendineae (B)</p> Signup and view all the answers

    What is the main function of the pulmonary circuit?

    <p>Transporting deoxygenated blood to the lungs (A)</p> Signup and view all the answers

    Which of the following statements accurately describes the function of the left ventricle?

    <p>Pumps oxygenated blood to the body (A)</p> Signup and view all the answers

    What is the name of the layer of tissue that forms the bulk of the heart wall?

    <p>Myocardium (B)</p> Signup and view all the answers

    The structure that separates the left and right atria is called the:

    <p>Interatrial septum (D)</p> Signup and view all the answers

    Which type of muscle tissue is found in the heart?

    <p>Cardiac muscle (C)</p> Signup and view all the answers

    What is the name of the fluid-filled space between the parietal and visceral layers of the pericardium?

    <p>Pericardial cavity (D)</p> Signup and view all the answers

    Which of the following valves prevents backflow of blood from the right ventricle into the right atrium?

    <p>Tricuspid valve (A)</p> Signup and view all the answers

    What is the name of the specialized cells in the heart that initiate and conduct electrical impulses?

    <p>Autorhythmic cells (B)</p> Signup and view all the answers

    The coronary circulation is responsible for:

    <p>Delivering oxygenated blood to the heart muscle (A)</p> Signup and view all the answers

    Which of the following statements is TRUE about the cardiac action potential plateau phase?

    <p>It is caused by a prolonged influx of calcium ions (Ca2+) (B)</p> Signup and view all the answers

    Which of the following components of the heart is NOT directly involved in the conduction system?

    <p>Papillary muscles (D)</p> Signup and view all the answers

    What is the name of the vessel that carries deoxygenated blood from the lower body to the right atrium?

    <p>Inferior vena cava (B)</p> Signup and view all the answers

    Which of the following statements is TRUE regarding the differences between cardiac muscle and skeletal muscle?

    <p>Cardiac muscle contracts more slowly than skeletal muscle (C)</p> Signup and view all the answers

    Which of the following structures are responsible for increasing the surface area of the atria?

    <p>Pectinate muscles (D)</p> Signup and view all the answers

    What is the term used to describe the ability of the heart to beat without external stimulation?

    <p>Autorhythmicity (B)</p> Signup and view all the answers

    Which of the following is NOT a factor that contributes to congestive heart failure (CHF)?

    <p>Decreased physical activity (C)</p> Signup and view all the answers

    The Atrial (Bainbridge) reflex is initiated by:

    <p>Increased blood flow in the atria (D)</p> Signup and view all the answers

    Which of the following statements is TRUE regarding heart rate regulation?

    <p>Heart rate generally decreases with age. (D)</p> Signup and view all the answers

    The Carotid Sinus Reflex primarily functions to:

    <p>Prevent major changes in blood supply to the brain (B)</p> Signup and view all the answers

    What is the primary effect of epinephrine and thyroxine on heart rate?

    <p>Increases heart rate (C)</p> Signup and view all the answers

    What is the term for the sequence of events associated with blood flow through the heart?

    <p>Cardiac cycle (D)</p> Signup and view all the answers

    Which phase of the cardiac cycle marks the beginning of ventricular relaxation?

    <p>Isovolumetric relaxation (D)</p> Signup and view all the answers

    What is the name of the brief rise in aortic pressure caused by the backflow of blood rebounding off the semilunar valves?

    <p>Dicrotic notch (B)</p> Signup and view all the answers

    What is the amount of blood remaining in a ventricle after contraction called?

    <p>End systolic volume (C)</p> Signup and view all the answers

    What does the QRS complex on an electrocardiogram (ECG) correspond to?

    <p>Ventricular depolarization (B)</p> Signup and view all the answers

    Which of the following is NOT a component of the cardiac cycle?

    <p>Blood pressure in the aorta (B)</p> Signup and view all the answers

    Which statement accurately describes the Frank-Starling Law of the Heart?

    <p>The strength of ventricular contraction is directly related to the degree of stretch of the cardiac muscle cells. (D)</p> Signup and view all the answers

    What is meant by the term 'afterload' in the context of the heart?

    <p>The pressure the ventricles must overcome to eject blood (B)</p> Signup and view all the answers

    Which of the following accurately describes the role of the atrioventricular (AV) node in the cardiac conduction system?

    <p>Delays the impulse to allow complete atrial contraction (A)</p> Signup and view all the answers

    What causes the rapid depolarization of the membrane potential in the initial phase of the action potential?

    <p>The opening of Na+ channels allowing Na+ influx (B)</p> Signup and view all the answers

    What is the primary reason for the plateau phase in the action potential?

    <p>Slow influx of Ca2+ ions (B)</p> Signup and view all the answers

    What is the primary mechanism responsible for repolarization of the membrane potential?

    <p>Inactivation of Na+ channels and opening of K+ channels (A)</p> Signup and view all the answers

    What is the role of the absolute refractory period in the action potential?

    <p>It prevents the generation of a new action potential during a previous one (C)</p> Signup and view all the answers

    Why is the membrane potential more positive during the plateau phase?

    <p>Due to the influx of Ca2+ ions (C)</p> Signup and view all the answers

    What is the significance of the tension development phase in the action potential?

    <p>It is the phase where the cell is contracting due to the influx of Ca2+ ions (A)</p> Signup and view all the answers

    What would happen if the K+ channels failed to open during repolarization?

    <p>The plateau phase would be prolonged (B)</p> Signup and view all the answers

    What is the primary difference between the absolute refractory period and the relative refractory period?

    <p>The absolute refractory period requires a stronger stimulus to generate a new action potential, while the relative refractory period does not (D)</p> Signup and view all the answers

    Flashcards

    Positive Feedback Cycle

    A process that amplifies signals, leading to rapid opening of Na+ channels.

    Membrane Potential (mV)

    The electrical charge difference across a cell membrane.

    Ca2+ Influx

    Movement of calcium ions into the cell, crucial for depolarization.

    Plateau Phase

    A steady state during cardiac muscle contraction when the membrane remains depolarized.

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    Repolarization

    The process when the cell membrane returns to its resting potential after depolarization.

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    K+ Efflux

    The movement of potassium ions out of the cell, restoring the resting potential.

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    Channel Inactivation

    The process where ion channels close and stop allowing ions to flow.

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    Absolute Refractory Period

    The time during which a new action potential cannot be initiated due to inactivation of Na+ channels.

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    Sinoatrial (SA) Node

    The heart's primary pacemaker that generates electrical impulses.

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    Atrioventricular (AV) Node

    Delays the electrical impulse to allow the atria to fully contract before ventricles.

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    QRS Complex

    An ECG representation of ventricular depolarization.

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    Cardiac Cycle

    All events associated with blood flow through the heart including contraction and relaxation.

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    Systole

    The phase of the cardiac cycle when the heart muscle contracts.

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    Diastole

    The relaxation phase of the cardiac cycle when the heart fills with blood.

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    Stroke Volume (SV)

    The amount of blood pumped by a ventricle with each heartbeat.

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    Cardiac Output (CO)

    The total amount of blood pumped by each ventricle in one minute.

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    Preload

    The degree to which cardiac muscle fibers are stretched before contraction.

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    Frank-Starling Law

    The principle that the stroke volume increases with increased preload.

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    Pericardium

    A double-walled sac around the heart made of fibrous connective tissue and serous membrane.

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    Epicardium

    The outer layer of the heart, also known as the visceral layer of the serous pericardium.

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    Myocardium

    The middle layer of the heart, composed of cardiac muscle tissue that contracts to pump blood.

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    Endocardium

    The innermost layer of the heart, lining the chambers and valves.

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    Atria

    The upper chambers of the heart that receive blood from the veins.

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    Ventricles

    The lower chambers of the heart that pump blood out to the lungs and body.

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    Atrioventricular valves

    Valves that regulate blood flow between atria and ventricles; includes the tricuspid and bicuspid valves.

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    Semilunar valves

    Valves that control blood flow from the ventricles to the arteries; includes pulmonary and aortic valves.

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    Coronary circulation

    The flow of blood to and from the tissues of the heart muscle itself.

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    Cardiac muscle

    Striated, branched muscle tissue that makes up the heart and is involuntary.

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    Autorhythmicity

    The ability of the heart muscle to generate its own rhythm without external stimuli.

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    Pacemaker cells

    Cells that initiate electrical impulses to regulate heartbeats.

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    Action potential

    An electrical signal that travels along cardiac cells, leading to contraction.

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    Intercalated discs

    Structures that connect cardiac muscle cells, allowing communication and synchronized contraction.

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    Atrial (Bainbridge) Reflex

    A sympathetic reflex triggered by increased blood volume in the atria, enhancing heart rate and cardiac output.

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    Carotid Sinus Reflex

    A reflex that prevents major blood supply changes to the brain, mediated by carotid sinus baroreceptors.

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    Chemical Regulation of the Heart

    The influence of hormones like epinephrine and thyroxine that increase heart rate and support ion balance.

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    Tachycardia

    An abnormally fast heart rate over 100 beats/min, which can lead to serious heart issues.

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    Congestive Heart Failure (CHF)

    A condition caused by various heart and blood vessel issues, leading to inadequate blood circulation.

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    Contractility

    The ability of the heart muscle to contract with strength, independent of muscle stretch.

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    Factors increasing contractility

    Includes increased sympathetic stimuli, certain hormones, calcium ions, and some drugs.

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    Factors decreasing contractility

    Includes acidosis, high extracellular potassium, and calcium channel blockers.

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    Sympathetic Nervous System (SNS)

    Part of the autonomic nervous system that increases heart rate during stress or exercise.

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    Parasympathetic Nervous System (PNS)

    Part of the autonomic nervous system that slows down the heart rate, promoting relaxation.

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    Cardioacceleratory Center (CAC)

    The sympathetic center that stimulates the heart to increase heart rate.

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    Cardioinhibitory Center (CIC)

    The parasympathetic center that inhibits the heart's activity, reducing heart rate.

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    Regulation of Heart Rate

    Heart rate is influenced by autonomic signals from both SNS and PNS, balancing heart activity.

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    Study Notes

    Heart Anatomy

    • The heart is located in the mediastinum, between the lungs.
    • It's positioned behind the sternum and above the diaphragm.
    • The apex of the heart points towards the left hip.
    • The heart is enclosed in a double-walled sac called the pericardium.
    • The inner layer, the epicardium, is a part of this sac.
    • The outer layer, the parietal pericardium, forms the outer protective barrier.
    • Fluid within the pericardial cavity minimizes friction during heart movements.

    Structure of the Heart Wall

    • The wall of the heart comprises three layers:
    • The epicardium (visceral pericardium). The outermost layer.
    • The myocardium. The middle layer forming most of the heart, containing cardiac muscle tissue.
    • The endocardium. The thin lining of the inner myocardial surface, continuous with the cardiovascular system's endothelium.
    • The fibrous skeleton of the heart is a fibrous connective tissue layer encircling the cardiac muscle.

    Heart Chambers

    • The heart has four chambers: two atria and two ventricles.
    • The atria receive blood returning to the heart.
    • The ventricles pump blood out of the heart.
    • Pectinate muscles are ridges within the right atrium.

    Heart Valves

    • Heart valves ensure unidirectional blood flow.
    • The atrioventricular valves (AV valves) are between the atria and ventricles.
    • The right AV valve is tricuspid, with three flaps.
    • The left AV valve is bicuspid (mitral) with two flaps.
    • Chordae tendineae connect the AV valve cusps to the papillary muscles.
    • Semilunar valves (SL valves) are between the ventricles and arteries leaving the heart.
    • The pulmonary semilunar valve is between the right ventricle and the pulmonary artery.
    • The aortic semilunar valve is between the left ventricle and the aorta.

    Blood Pathway Through the Heart and Lungs

    • Deoxygenated blood arrives at the right atrium via superior and inferior vena cava.
    • It then flows through the tricuspid valve to the right ventricle.
    • The right ventricle pumps blood through the pulmonary semilunar valve to the pulmonary artery towards the lungs.
    • In the lungs, blood is oxygenated.
    • Oxygenated blood returns to the left atrium through pulmonary veins.
    • It passes through the bicuspid valve to the left ventricle.
    • The left ventricle pumps blood through the aortic semilunar valve to the aorta and onward to systemic circulation.

    Heart Valves Function

    • AV valves open when atrial pressure exceeds ventricular pressure, allowing blood flow into the ventricles.
    • AV valves close when ventricular pressure exceeds atrial pressure to prevent backflow.
    • SL valves open when ventricular pressure exceeds arterial pressure, allowing blood ejection into the arteries.
    • SL valves close when ventricular pressure falls below arterial pressure to prevent backflow into the ventricles.

    Coronary Circulation

    • This is the functional blood supply to the heart muscle itself.
    • Coronary arteries branch from the aorta and supply oxygenated blood to the myocardium.
    • Coronary veins collect deoxygenated blood and return it to the coronary sinus, which empties into the right atrium.

    Cardiac Muscle

    • Cardiac muscle is striated, branched, and interconnected.
    • Cardiac muscle cells are uni- or binucleate.
    • Intercalated discs join cardiac cells and transmit impulses between cells, allowing for synchronized contraction.
    • Cardiac muscle contracts as a functional syncytium.
    • Cardiac muscle tissue is self-excitable (autorhythmic).

    Cardiac Muscle Contraction

    • Depolarization leads to Ca2+ influx, a prolonged process generating a plateau phase.
    • Repolarization results from inactivation of Ca2+ channels and opening of voltage-gated K+ channels.
    • Cardiac muscle action potentials last much longer than skeletal muscle potentials.

    Heart Physiology: Intrinsic Conduction System

    • The intrinsic conduction system is the specialized network that coordinates the heartbeat.
    • Autorhythmic cells have unstable resting potentials called pacemaker potentials.
    • The SA node (sinoatrial node), the heart's pacemaker, initiates action potentials.

    Heart Physiology: Sequence of Excitation

    • The SA node generates electrical impulses, initiating atrial depolarization approximately 75 times per minute.
    • The AV node delays the impulse approximately 0.1 second.
    • The impulse then travels to the AV bundle, which branches into the bundle branches and Purkinje fibers in the interventricular septum and walls.

    Electrocardiography (ECG)

    • ECG records the electrical activity of the heart.
    • The P wave represents atrial depolarization, QRS represents ventricular depolarization, and the T wave represents ventricular repolarization.
    • Atrial repolarization is obscured by the QRS complex.

    Cardiac Cycle

    • The cardiac cycle includes all events associated with blood flow through the heart. It contains electrical, mechanical events and phases such as systole and diastole.
    • Phases of the cardiac cycle include: ventricular filling, atrial systole, ventricular systole, and isovolumetric relaxation.

    Cardiac Output (CO)

    • Cardiac output (CO) is the amount of blood pumped out by each ventricle in one minute.
    • CO is directly correlated to the product of heart rate (HR) and stroke volume (SV).

    Stroke Volume (SV)

    • SV is the volume of blood pumped out of one ventricle per contraction.
    • SV is determined by the difference between end-diastolic volume (EDV) and end-systolic volume (ESV).

    Factors Affecting Stroke Volume

    • Preload is the amount of stretching of the cardiac muscle cells before contraction (related to EDV).
    • Contractility is the force of contraction independent of stretch.
    • Afterload is the resistance against which the ventricles pump blood during systole.
    • Increased sympathetic stimulation and certain hormones increase contractility, whereas acidosis and increased extracellular K+ decrease it.

    Regulation of Heart Rate-Autonomic Nervous System

    • The autonomic nervous system (ANS) governs heart rate.
    • The sympathetic nervous system increases heart rate (accelerates).
    • The parasympathetic nervous system decreases heart rate (inhibits), mediated by acetylcholine.

    Extrinsic Factors Affecting Cardiac Output

    • Various factors, like exercise, body temperature, age, and gender affect the heart rate.

    Homeostatic Imbalance

    • Tachycardia is an abnormally fast heart rate.
    • Bradycardia is an abnormally slow heart rate.

    Congestive Heart Failure (CHF)

    • Congestive heart failure (CHF) is a condition in which the pumping efficiency of the heart is impaired.
    • CHF can be brought on from several factors, including coronary atherosclerosis, persistent high blood pressure and others.

    Cardiac Conditioning

    • Exercise increases cardiac muscle mass.
    • Cardiac muscle mass increase contributes to increased strength of contraction
    • Increased conditioning results in less frequent heartbeat and a greater resting period.

    Special Cardiovascular Reflexes

    • Atrial (Bainbridge) reflex is a sympathetic reflex initiated by increased blood volume within the atria.
    • Carotid sinus reflex and aortic sinus reflex control blood flow to the brain and systemic circulation using baroreceptors.

    Chemical Regulation of the Heart

    • Hormones like epinephrine and thyroxine can directly influence heart rate among other factors.

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    Description

    Test your knowledge of the cardiovascular system with this quiz focused on cardiac output, contractility, heart rate regulation, and more. Dive into the roles of various hormones and nervous system influences on heart function. Perfect for students of anatomy and physiology!

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