Cardiovascular System - Lecture 11

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Questions and Answers

What is the primary function of the pressure gradient in the cardiovascular system?

  • To move blood through the circulation (correct)
  • To generate electrical impulses in the heart
  • To regulate body temperature
  • To convert oxygen into carbon dioxide

During which phase does the pressure in the right ventricle reach approximately 15-30 mmHg?

  • Right ventricle systole (correct)
  • Left atrium diastole
  • Left ventricle systole
  • Right atrium diastole

What does MAP stand for in the context of blood pressure values?

  • Median Average Pressure
  • Minimum Arterial Perfusion
  • Mean Arterial Pressure (correct)
  • Maximum Arterial Pressure

How is pulse pressure calculated?

<p>Systolic Pressure - Diastolic Pressure (D)</p> Signup and view all the answers

What role do elastic arteries play in the cardiovascular system?

<p>They act as pressure reservoirs (D)</p> Signup and view all the answers

What is the normal blood pressure value typically recorded at the brachial artery?

<p>120 / 70 mmHg (A)</p> Signup and view all the answers

What is the main purpose of the cardiac cycle?

<p>To coordinate the contraction and relaxation of heart chambers (D)</p> Signup and view all the answers

Which side of the heart operates at higher pressure during the cardiac cycle?

<p>Left side only (A)</p> Signup and view all the answers

What is the primary function of the cardiovascular system?

<p>To transport nutrients and remove waste products (B)</p> Signup and view all the answers

Which of the following factors does NOT influence the flow of blood from one point to another?

<p>Temperature of the surrounding environment (D)</p> Signup and view all the answers

What is represented by the term 'ΔP' in the context of blood flow?

<p>The pressure difference between two points (D)</p> Signup and view all the answers

Which phase of the cardiac cycle is associated with the heart's electrical activity as observed in an ECG?

<p>Systole (B)</p> Signup and view all the answers

What physiological principle explains the relationship between pressure difference, flow rate, and resistance in the cardiovascular system?

<p>Darcy's Law (B)</p> Signup and view all the answers

How does the heart contribute to blood pressure?

<p>By generating a pressure wave during contraction (C)</p> Signup and view all the answers

Which of the following best describes vascular resistance?

<p>The opposition to blood flow through the circulatory system (B)</p> Signup and view all the answers

What is measured to determine blood pressure?

<p>Pressure at systole and diastole (C)</p> Signup and view all the answers

What initiates the contraction of the heart during the cardiac cycle?

<p>Sinoatrial node activation (D)</p> Signup and view all the answers

Which phase of the cardiac cycle involves the heart relaxing and filling with blood?

<p>Diastole (D)</p> Signup and view all the answers

What is the purpose of the Atrioventricular (AV) node in the cardiac conduction system?

<p>To delay impulses allowing for atrial contraction (A)</p> Signup and view all the answers

During which part of the cardiac cycle does the aortic valve open?

<p>Ventricular Systole (A)</p> Signup and view all the answers

What occurs during Isovolumic contraction?

<p>Ventricles contract without blood volume change (A)</p> Signup and view all the answers

What is detected by an electrocardiogram (ECG)?

<p>Electrical activity across the heart (C)</p> Signup and view all the answers

The T wave on an ECG represents which event?

<p>Ventricular repolarization (B)</p> Signup and view all the answers

What is the primary factor that drives blood flow through the heart during the cardiac cycle?

<p>Pressure gradients within the chambers (A)</p> Signup and view all the answers

What does the QRS complex in an ECG primarily represent?

<p>Ventricular depolarization (C)</p> Signup and view all the answers

What is the primary role of the Bundle of His in the cardiac conduction system?

<p>Coordinating ventricular contractions (A)</p> Signup and view all the answers

Which phase marks the beginning of the cardiac cycle?

<p>Ventricular diastole (B)</p> Signup and view all the answers

What event triggers the closure of the aortic valve?

<p>Decrease in left ventricle pressure (B)</p> Signup and view all the answers

During which phase does passive filling of the ventricles occur?

<p>Diastole (B)</p> Signup and view all the answers

Flashcards

Cardiovascular Pressure Gradient

The difference in pressure between two points in the circulatory system.

Pressure Gradient from Heart Contraction

The heart's contraction generates pressure driving blood through the circulatory system. It is highest in the left ventricle during systole.

Elastic Arteries as Pressure Reservoirs

Elastic arteries expand during systole and recoil during diastole, helping to maintain blood flow.

Pressure Gradient and Blood Flow Direction

The pressure difference between the heart and the tissues drives blood flow from the heart to the rest of the body.

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Blood Pressure

The pressure within the arteries, measured at the brachial artery.

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Systolic Pressure

The highest pressure in the arteries, when the heart contracts.

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Diastolic Pressure

The lowest pressure in the arteries, when the heart relaxes.

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Mean Arterial Pressure (MAP)

The average pressure in the arteries over one cardiac cycle. Calculated as Diastolic Pressure plus 1/3 of Pulse Pressure.

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Cardiac Cycle

A series of electrical and mechanical events that coordinate blood flow through the heart and into circulation during one heartbeat.

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Cardiac Conduction System

The specialized tissue in the heart responsible for generating and conducting electrical impulses that initiate and coordinate contraction and relaxation.

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Systole

The period during which the heart muscle contracts, expelling blood from the chambers.

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Diastole

The period during which the heart muscle relaxes, allowing chambers to refill with blood.

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Pacemaker Cells

The specialized cells in the heart that initiate and regulate the heartbeat. They are responsible for generating electrical impulses.

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Sinoatrial (SA) Node

The primary pacemaker of the heart located in the right atrium. It generates electrical impulses for the heart to contract.

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Atrioventricular (AV) Node

The region in the heart that acts as a gate between the atria and ventricles, slowing down electrical impulses to allow the atria to completely contract before the ventricles.

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Bundle of His

A pathway that carries electrical impulses from the AV node to the ventricles, ensuring coordinated ventricular contraction.

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Bundle Branches

The branches of the Bundle of His that spread out to the ventricles, further distributing electrical impulses for coordinated contraction.

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Purkinje Fibers

Fibers in the ventricles that receive electrical impulses from the bundle branches and rapidly distribute them to all parts of the ventricular muscle, ensuring coordinated contraction.

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Electrocardiogram (ECG)

A recording of the electrical activity of the heart, reflecting the depolarization and repolarization of cardiac muscle cells during the cardiac cycle.

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P Wave

The first wave on an ECG that represents atrial depolarization, leading to atrial contraction.

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QRS Complex

The complex on an ECG that represents ventricular depolarization, leading to ventricular contraction.

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T Wave

The wave on an ECG that represents ventricular repolarization, leading to ventricular relaxation.

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Ventricular Systole

The period during which the heart's ventricles contract, increasing internal pressure, leading to the opening of the aortic valve and ejection of blood into the aorta for circulation.

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What is the main function of the cardiovascular system?

The cardiovascular system is responsible for transporting blood throughout the body, delivering essential nutrients and oxygen to tissues while removing waste products.

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What are the components of the cardiovascular system?

The cardiovascular system consists of the heart, blood vessels (arteries, veins, capillaries), and blood.

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What is haemodynamics?

Haemodynamics is the study of blood flow and the forces that govern it. It involves understanding how blood pressure, vessel diameter, and blood viscosity influence blood flow.

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What is the pressure difference (ΔP) in blood flow?

Pressure difference (ΔP) is the difference in pressure between two points in a blood vessel, driving blood from the higher pressure area to the lower pressure area.

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What is vascular resistance in blood flow?

Vascular resistance opposes blood flow and is determined by factors like vessel diameter, blood viscosity, and vessel length. Narrower vessels and thicker blood create more resistance.

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What is Darcy's Law?

Darcy's Law states that the flow of a fluid (blood) through a porous medium (blood vessels) is directly proportional to the pressure difference and inversely proportional to the resistance. This means higher pressure difference leads to higher flow, while higher resistance leads to lower flow.

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What is the cardiovascular pressure gradient?

The cardiovascular pressure gradient refers to the difference in blood pressure between the heart and the rest of the body. This pressure gradient drives blood flow from the heart to the tissues.

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What are blood pressure values?

Blood pressure values are measures of the force of blood against the walls of blood vessels. They are typically expressed as systolic pressure over diastolic pressure (e.g., 120/80 mmHg).

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Study Notes

Cardiovascular System - Lecture 11: Circulation of Blood

  • The cardiovascular system's function is to maintain an adaptable blood supply to tissues, delivering nutrients and signaling molecules, and removing waste products.
  • This is achieved by generating pressure differentials across tissues to facilitate capillary exchange.
  • The lecture covers the components and function of the cardiovascular system.
  • It also outlines the general features of blood circulation and the principles of haemodynamics involved in blood flow.
  • The role of the heart in creating pressure waves and measuring blood pressure is discussed.
  • The cardiac cycle, the cardiac conduction system, and the electrocardiogram (ECG) as mechanics of blood flow are detailed.

Objectives

  • Students should be able to describe the components and function of the cardiovascular system, along with general circulation features.
  • They should describe general principles of haemodynamics and blood flow.
  • Students should recall the heart's role in generating pressure waves and describe blood pressure measurement methods.
  • They should describe the cardiac cycle, cardiac conduction system, and the electrocardiogram (ECG).

Content Outline

  • Introduction to the Cardiovascular System
  • Haemodynamics - The Physics of Blood Flow
    • Pressure
    • Vascular Resistance
  • The Cardiovascular Pressure Gradient
  • Blood Pressure Values
  • The Cardiac Cycle
    • Electrical Events (ECG)
    • Mechanical Events

What Does the Cardiovascular System Do?

  • Delivers oxygen and nutrients to the body's tissues.
  • Removes waste products from tissues.

Function of the Cardiovascular System

  • To maintain an adaptable blood supply to tissues.
  • To supply nutrients and signaling molecules and remove waste products.
  • To achieve this, it creates pressure differences across tissues to permit capillary exchange.

Components of the Cardiovascular System

  • Heart: Cardiac output.
  • Blood vessels: Arterial blood pressure, Peripheral resistance, capillary pressure, venous pressure, Blood vessels. Regulation by brain, neural and hormonal influences.

Haemodynamics - The Physics of Blood Flow

  • Blood flow (F) is determined by pressure difference (ΔP) and resistance (R): F = ΔP/R
  • Darcy's Law illustrates fluid flow through a porous medium.

Vascular Resistance

  • Resistance to blood flow is dependent on vessel length (L), vessel radius (r), and blood viscosity (η).
  • Flow is proportional to the radius to the power of four (r4).
  • Changes in vessel radius significantly impact blood flow.
  • The Hagen-Poiseuille equation (F = ΔP. Πr4 / 8Lη) describes blood flow.

Blood Pressure Values

  • Systolic: the top number, arterial pressure during ventricular contraction.
  • Diastolic: bottom number, arterial pressure during ventricular relaxation.
  • BP values (e.g., 120/80 mmHg) are measured at the brachial artery.
  • Different ranges (e.g., high blood pressure, ideal blood pressure) are categorized for health assessment.

Cardiac Cycle

  • The sequence of electrical and mechanical events during one heartbeat.
  • Electrical Events (ECG):
    • P wave: atrial depolarization
    • QRS complex: ventricular depolarization
    • T wave: ventricular repolarization
  • Mechanical Events:
    • Contraction and relaxation phases of the heart chambers.
    • Valve opening and closing, with pressure gradients impacting flow.
  • The pressure-volume changes describe various phases of the cardiac cycle: late diastole, atrial systole, ventricular systole, and ventricular diastole. Measurements of pressure and volume associated with each of these phases are essential to understand the cycle.

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