Cardiovascular System: Key Terms and Processes

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Questions and Answers

Which of the following best describes the role of troponin in muscle contraction?

  • It directly binds to actin, causing the filaments to shorten.
  • It provides the energy for the power stroke of the myosin head.
  • It blocks the active site on actin, preventing myosin from binding in a relaxed muscle.
  • It anchors tropomyosin to actin filaments and regulates myosin binding. (correct)

A patient is diagnosed with ventricular fibrillation. What is the primary issue occurring in the heart?

  • The ventricles are quivering erratically, resulting in ineffective blood pumping. (correct)
  • The ventricles are contracting too forcefully, leading to increased blood pressure.
  • The ventricles are contracting in a coordinated, but rapid, manner.
  • The ventricles are blocked, preventing blood from exiting the heart.

What is the fundamental difference between cardiac muscle and skeletal muscle?

  • Cardiac muscle is under voluntary control, while skeletal muscle is involuntary.
  • Cardiac muscle cells are connected by intercalated discs, allowing for coordinated contraction, while skeletal muscle fibers are independent. (correct)
  • Cardiac muscle contains multiple nuclei per cell, while skeletal muscle contains only one.
  • Cardiac muscle uses only aerobic metabolism, while skeletal muscle uses only anaerobic metabolism.

If a patient's blood pressure is consistently high (hypertension), what long-term effect can this have on the heart?

<p>Left ventricular hypertrophy due to increased afterload. (B)</p> Signup and view all the answers

How does the baroreceptor reflex respond to a sudden drop in blood pressure?

<p>By increasing heart rate and vasoconstriction. (C)</p> Signup and view all the answers

What is the primary function of the circle of Willis in the brain?

<p>To provide an alternative route for blood flow to the brain if one of the major arteries is blocked. (D)</p> Signup and view all the answers

In the context of blood flow, what is the primary difference between laminar and turbulent flow?

<p>Laminar flow is smooth and orderly, while turbulent flow is chaotic and irregular. (B)</p> Signup and view all the answers

During cardiac muscle contraction, what is the role of the intrinsic conduction system?

<p>To coordinate and synchronize the contraction of the atria and ventricles (A)</p> Signup and view all the answers

What is the significance of the angiotensin system in regulating blood pressure?

<p>It raises blood pressure by promoting vasoconstriction and increasing sodium retention. (D)</p> Signup and view all the answers

Which of the three types of capillaries is characterized by having the leakiest structure, allowing for the passage of large molecules and even cells?

<p>Sinusoidal capillaries (A)</p> Signup and view all the answers

Flashcards

Fibrinogen to Fibrin

The conversion of fibrinogen to fibrin is the final step in the coagulation cascade, where soluble fibrinogen is converted into insoluble fibrin, forming a mesh that stabilizes a blood clot.

Clotting vs. Clumping

Clotting is the physiological process of forming a blood clot to stop bleeding, while clumping (agglutination) is the aggregation of cells or particles, often due to an immune response.

Increased Vascular Resistance

Increased resistance in a blood vessel leads to decreased blood flow and increased blood pressure, potentially causing hypertension and increased workload on the heart.

What is an ionotrope?

An ionotrope is an agent that alters the force or energy of muscular contractions. Negative ionotropes weaken the force of muscular contractions. Positive ionotropes increase the force of muscular contractions

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Chronotrope definition

Chronotrope or chronotrophic refers to the rate of heart contractions. Positive chronotropes increase heart rate. Negative chronotropes decreases heart rate.

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Formed Elements of Blood

Formed elements of blood include erythrocytes (RBCs), leukocytes (WBCs), and thrombocytes (platelets). Erythrocytes transport oxygen, leukocytes are involved in immune responses, and thrombocytes facilitate blood clotting.

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Blood Flow in Capillaries

Blood flows through capillaries via pressure gradients, moving from arterioles (higher pressure) to venules (lower pressure), facilitating the exchange of gases, nutrients, and wastes.

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Blood Pressure

Blood pressure is the force exerted by blood against the walls of blood vessels; measured using a sphygmomanometer to determine systolic and diastolic pressures, typically expressed in mmHg.

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What is an EKG/ECG?

An ECG or EKG records the electrical activity of the heart over time. Key components include P wave (atrial depolarization), QRS complex (ventricular depolarization), and T wave (ventricular repolarization).

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Venous Return Against Gravity

Blood flows from the leg back to the heart against gravity via mechanisms such as venous valves (preventing backflow), skeletal muscle contractions (muscle pump), and respiratory movements (thoracic pump).

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Study Notes

  • Definitions and terms mentioned in lecture notes are important to know.
  • Important terms are often bolded.

Fibrinogen to Fibrin Conversion

  • Fibrinogen converts to fibrin during blood clot formation.

Capillary Types

  • There are three types of capillaries.
  • Capillaries differ based on location in the body
  • Important to understand how capillary structure affects the organ/system they are located within

Blood Clot Formation

  • Describe blood clot formation

Clotting vs. Clumping (Agglutination)

  • Differentiate between clotting and clumping.
  • Clotting is the process of blood coagulating to seal damaged vessels; Clumping is the aggregation of cells.

Physiological Processes Influencing Heart Rate (HR)

  • Physiological processes influence heart rate.
  • The parasympathetic nervous system decreases HR.
  • The sympathetic nervous system increases HR.
  • Changes in HR can affect stroke volume and cardiac output.

Increased Resistance in a Blood Vessel

  • Increased resistance in a blood vessel affects hemodynamics.

Sam's Diagnosis

  • Sam has chest pains and elevated creatine phosphate, lactic acid, and troponin.
  • Troponin anchors tropomyosin to actin filaments.
  • Sam may be experiencing a myocardial infarction (heart attack).
  • Treatment may involve medications and/or procedures to restore blood flow.

Ionotrope

  • Define what an ionotrope is

Chronotrope/Chronotrophic

  • Define chronotrope and/or chronotrophic

Mary Beth's Diagnosis

  • Mary Beth experiences angina, shortness of breath, fatigue, and dizzy spells.
  • She has an irregular heart rhythm and skin color changes, and an anomaly in the left atrium and AV valve.
  • Likely diagnosis is mitral valve stenosis

Formed Elements in Blood

  • List and describe all formed elements of the blood

Types of Shock

  • Compare and contrast all types of shock

Blood Flow Through The Heart

  • Describe blood flow

Electrical Conduction System of the Heart

  • Describe the electrical conduction of the heart

Development of the Heart

  • Know the stages etc involved in heart development

Erythrocyte Maturation

  • Explain how red blood cells (erythrocytes) mature

RBC Breakdown and Recycling

  • Outline which organs breakdown and recycle

Blood Types (ABO and Rh System)

  • Know all the blood types (ABO system and Rh- system) and be able to fill in a chart.

Capillaries in the Body

  • List where the capillaries are located in the body

Pulmonary, Systemic, and Coronary Circulation

  • Compare and contrast these three types of circulation

Pericardium

  • Define pericardium

Myocardium

  • Know the function of the myocardium

Cardiac vs. Skeletal Muscle

  • Compare and contrast cardiac and skeletal muscle

Intrinsic Conduction System of the Heart

  • Describe intrinsic conduction of the heart

Cardiac Depolarization and Repolarization

  • Describe the events

Arteries

  • What are the different types

Capacitance Vessel

  • Define what capacitance vessel is

EKG or ECG

  • What is an EKG/ECG

Heart Murmurs

  • What are they and describe them

Ventricular Fibrillation

  • Define ventricular fibrillation

A Fib

  • Define A fib

AV Node Block

  • Definition for AV Node Block

Laminar vs. Turbulent Flow

  • What are the differences

Turbulent Flow

  • What causes it

Tunic Associated with Blood Vessels

  • Describe what it is

Blood Flow Through a Capillary

  • Detail blood flow

Blood Pressure

  • Define what it is and what it is measured by

Blood Flow Back to Heart Against Gravity

  • Explanations of how?

Circle of Willis

  • Define circle of willis

Blood Transfusion

  • What happens if someone needs it

Resistance

  • What is resistance

Types of Shock

  • Different types

Angiotensin System

  • Explain the significance

Hypertension

  • What does it entail

Baroreceptor Reflex

  • What does it entail

CO

  • What does it entail

Blood Pressure

  • What does it entail

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