Cardiovascular Physiology: Introduction

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Questions and Answers

Which of the following best describes the primary function of arteries within the cardiovascular system?

  • Transport blood away from the heart to various organs and tissues of the body. (correct)
  • Serve as the primary reservoirs for blood volume within the circulatory system.
  • Return blood from the rest of the body to the heart.
  • Facilitate the exchange of nutrients and waste at the cellular level.

What is the role of capillaries in the cardiovascular system?

  • Exchanging nutrients and waste products between blood and tissues. (correct)
  • Acting as a low-pressure return system to the heart.
  • Regulating blood flow based on hormonal signals.
  • Distributing blood under high pressure to distant organs.

How do veins contribute to the circulatory process?

  • Filtering toxins from the blood.
  • Storing and releasing blood to control blood pressure.
  • Allowing blood to flow one-way back to the heart. (correct)
  • By actively pumping blood to tissues.

Which component of the cardiovascular system is primarily responsible for the transport of oxygen, nutrients, and hormones?

<p>Blood (C)</p> Signup and view all the answers

What is a key function of the cardiovascular system in maintaining homeostasis?

<p>Regulating body temperature and blood flow. (A)</p> Signup and view all the answers

What is the role of the cardiovascular system in relation to metabolic wastes?

<p>It facilitates the rapid removal (washout) of metabolic wastes. (B)</p> Signup and view all the answers

How does the cardiovascular system contribute to immune function?

<p>By transporting immune cells and molecules to sites of infection or injury. (B)</p> Signup and view all the answers

What is the pericardium, and what role does it play in the heart's function?

<p>It is a double-walled sac that encloses the heart, providing protection and lubrication. (C)</p> Signup and view all the answers

How does the pericardial fluid contribute to the functionality of the heart?

<p>It reduces friction between the heart and the surrounding structures during contraction. (D)</p> Signup and view all the answers

Apart from reducing friction, what additional protective role does the pericardium serve?

<p>It prevents sudden over-distension of the heart chambers. (B)</p> Signup and view all the answers

Which layer of the heart wall is primarily responsible for the heart's pumping action?

<p>Myocardium (C)</p> Signup and view all the answers

What is the main characteristic of the endocardium's structure and function?

<p>It is a single layer of endothelial cells that lines the inner surface of the heart. (B)</p> Signup and view all the answers

How does the structure of the endocardium facilitate its function within the heart?

<p>Its smooth surface reduces friction as blood flows through the heart. (B)</p> Signup and view all the answers

What is the key structural difference between atria and ventricles, linked to their function?

<p>Ventricles are generally thicker-walled compared to the atria. (D)</p> Signup and view all the answers

What is the functional significance of atria being thin-walled?

<p>Enables them to receive blood returning to the heart with minimal resistance. (B)</p> Signup and view all the answers

How does the thicker-walled structure of the ventricles relate to their function?

<p>It enables powerful contractions to pump blood to the lungs and the rest of the body. (A)</p> Signup and view all the answers

Where does the right atrium receive blood from?

<p>Superior and inferior vena cavae and coronary sinus (D)</p> Signup and view all the answers

Which vessels deliver blood into the left atrium?

<p>Pulmonary veins (D)</p> Signup and view all the answers

What is the primary function of the ventricles within the heart?

<p>To pump blood into the arteries. (C)</p> Signup and view all the answers

How many valves are present in the human heart, and what is their general function?

<p>Four valves; to ensure unidirectional blood flow. (C)</p> Signup and view all the answers

Where are the atrioventricular valves located, and what is their primary function?

<p>Between the atria and ventricles; to prevent backflow into the atria. (B)</p> Signup and view all the answers

What is the role of the mitral valve, and where it is located?

<p>To prevent backflow from the left ventricle to the left atrium. (B)</p> Signup and view all the answers

What is the function of the tricuspid valve?

<p>Preventing backflow of blood from the right ventricle into the right atrium. (B)</p> Signup and view all the answers

Where are the semilunar valves located, and what is their function?

<p>At the exits of the ventricles; preventing backflow into the ventricles. (C)</p> Signup and view all the answers

Which valve prevents backflow of blood from the aorta into the left ventricle?

<p>Aortic valve (C)</p> Signup and view all the answers

What is the role of the pulmonary valve in the circulatory system?

<p>To prevent backflow of blood from the pulmonary artery into the right ventricle. (C)</p> Signup and view all the answers

What are the two main circuits of the cardiovascular system?

<p>Systemic and pulmonary (A)</p> Signup and view all the answers

What is the primary function of the pulmonary circulation?

<p>Transporting deoxygenated blood to the lungs. (B)</p> Signup and view all the answers

What happens to blood in the pulmonary circulation?

<p>It absorbs oxygen and releases carbon dioxide. (B)</p> Signup and view all the answers

Which of the following describes the systemic circulation?

<p>The movement of blood between the heart and the rest of the body. (B)</p> Signup and view all the answers

In which order does blood flow through the following structures: right atrium, lungs, right ventricle?

<p>Right atrium → right ventricle → lungs (B)</p> Signup and view all the answers

Through which valve does blood pass after leaving the right atrium?

<p>Tricuspid valve (D)</p> Signup and view all the answers

Which valve does blood pass through as it enters the left ventricle?

<p>Mitral valve (D)</p> Signup and view all the answers

What is the pathway of blood flow after it leaves the left ventricle?

<p>Aorta to the systemic circulation (C)</p> Signup and view all the answers

Which of the following best describes valvular regurgitation?

<p>A valve that does not close properly, leading to backflow of blood. (B)</p> Signup and view all the answers

What is a common symptom associated with valvular regurgitation?

<p>Whistling sound. (D)</p> Signup and view all the answers

In the context of valvular pathologies, what defines stenosis?

<p>Narrowed valve opening reducing blood flow. (B)</p> Signup and view all the answers

What audible sign is typically associated with stenosis during a cardiac auscultation?

<p>A swishing sound. (C)</p> Signup and view all the answers

Flashcards

Cardiovascular System

The system that refers to the passages through which the blood flows.

Heart

A pumping organ that is the driving force for the cardiovascular system.

Blood Vessels

Passage ways in the cardiovascular system, including arteries, capillaries and veins.

Arteries

Channels that distribute blood to the organs.

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Capillaries

An exchange region in the cardiovascular system.

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Veins

Blood reservoirs that return blood to the heart.

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Blood

The transport medium within the cardiovascular system.

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The Heart

The muscular pump that forces blood through arteries, veins, and capillaries.

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Pulmonary circulation

The blood circulatory route that moves blood between the heart and the lungs.

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Systemic circulation

The systemic circulation moves blood between the heart and the rest of the body.

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Pericardium

The layer that encloses the heart in a double-walled sac.

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Epicardium

The outer most layer of the wall of the heart.

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Myocardium

The middle layer of the heat wall.

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Endocardium

The innermost layer of the heart wall.

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Atria

Two thin-walled muscular sheaths.

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Ventricles

Thicker-walled portion of the heart.

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Coronary Sinus

A collection of veins joined together that collects blood from the heart muscle.

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Heart Valves

Permit the flow of blood through the heart in only one direction.

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Atrioventricular Valves

Found between the atria and the ventricles.

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Semilunar Valves

Placed at the opening of blood vessels arising from the ventricles.

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Mitral (Bicuspid) Valve

Lies between the left atrium and left ventricle.

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Tricuspid Valve

Lies between the right atrium and right ventricle.

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Semilunar valves

Located at the exits of the right and left ventricles.

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Pulmonary Valve

Allows blood to flow into the pulmonary artery.

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Aortic Valve

Allows blood to flow into the aorta that directs blood to the body

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Regurgitations

Blood goes in backward direction in heart due to failing valve.

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Stenosis

Valve does not open completely

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Study Notes

  • Cardiovascular physiology Introduction, presented by Dr. Ateeqa Younis

Introduction to Cardiovascular System (CVS)

  • Refers to the passages through which blood flows
  • Made up of the heart, blood vessels, and blood

Components of the CVS

  • The heart serves as the driving force for CVS
  • Blood vessels serve as passage ways
  • Arteries are distribution channels distributing blood flow to organs
  • Capillaries are the exchange region
  • Veins are blood reservoirs for directing blood flow back to the heart
  • Blood is the transport medium for the system

General Functions of CVS

  • Transports: O2, nutrients, water, hormones, electrolytes, and drugs
  • Enable rapid washout of metabolic wastes
  • Help to regulate temperature and blood flow
  • Help with defense mechanisms

Heart Anatomy

  • Gross anatomy includes the superior vena cava, right pulmonary artery, pulmonary trunk, right atrium, right pulmonary veins, fossa ovalis, pectinate muscles, tricuspid valve, right ventricle, chordae tendineae, trabeculae carneae, and inferior vena cava

Heart as a Dual Pump

  • Muscular pump responsible for forcing blood through arteries, veins, and capillaries
  • Is a dual pump driving blood in two consecutive circuits
  • The systemic and pulmonary circulations are part of these circuits
  • Receives blood from the rest of the body through the vena cava

Circulation: Pulmonary

  • Pulmonary circulation moves blood between heart and lungs
  • Transports deoxygenated blood to lungs to absorb oxygen and release carbon dioxide
  • Oxygenated blood then flows back to heart

Circulation: Systemic

  • Systemic circulation moves blood between the heart and the rest of the body

Outer Surface Layers: Pericardium

  • Heart enclosed within a double-walled sac referred to as the pericardium
  • Consists of clear pericardial fluid inside, about 30-50ml
  • Barrier to infection
  • Provides lubrication
  • Prevents sudden over-distention of heart chamber

Layers of the Heart Wall

  • There are three layers of the heart wall
  • Epicardium: outermost layer of the heart wall
  • Myocardium: second layer, lies under epicardium, responsible for the bulk of the heart mass, enables the pumping action
  • Endocardium: innermost layer of heart wall, formed by a single layer of endothelial cells, continues as the endothelium of blood vessels

Heart Chambers: Features

  • Is comprised of four chambers
  • Two atria and two ventricles
  • Atria have thin-walled muscular sheaths
  • Blood returns to the heart at the two superior chambers, the right and left atria
  • Blood enters right atria from superior and inferior vena cavae and coronary sinus
  • Blood enters left atria from pulmonary veins
  • Ventricles are the thicker-walled portion of the heart
  • Right and left ventricles are pumps ejecting blood into the arteries
  • Coronary sinus is collection of veins connecting to form a vessel for collecting blood from heart muscle
  • Delivers less-oxygenated blood to the right atrium, like the superior and inferior venae cavae

The Right Heart

  • Comprises of the right atrium and right ventricle
  • Right atrium receives venous blood from systemic circulation
  • Right ventricle pumps blood into pulmonary circulation

The Left Heart

  • Comprises of the left atrium and the left ventricle
  • Left atrium receives blood from lungs by the pulmonary veins
  • Left ventricle ejects blood into the aorta which distributes blood to organs via the arterial system

Heart Valves

  • Permit flow of blood through heart in one direction
  • Valves are needed for pumping blood effectively and ensure a predominantly one-way flow
  • Human heart has four valves

Types of Heart Valves

  • Two atrioventricular valves found between atria and ventricles
  • Two semilunar valves, placed at opening of vessels arising from ventricles, specifically systemic aorta and pulmonary artery

Atrioventricular Valves: Mitral

  • Mitral (bicuspid) valve located between left atrium and left ventricle
  • Responsible for preventing backflow of blood from the LV to the LA

Atrioventricular Valves: Tricuspid

  • Tricuspid valve (three cusps) lies between right atrium and right ventricle
  • Responsible for preventing backflow of blood from the RV to RA

Semilunar Valves: Aortic

  • Aortic valves are located at the exits of right and left ventricles
  • Enable blood to flow into aortic tree and eventually into the left and right main coronary arteries
  • Prevent backflow of blood from the aorta to the LV

Semilunar Valves: Pulmonary

  • Enable blood to flow into pulmonary artery
  • Prevent the back flow of blood from PA to the RV

Heart Valve Blood Flow Mechanism

  • When pressure is greater behind the valve, it opens
  • When pressure is greater in front of the valve, it closes
  • Valves only open in one direction

Heart Valve Blood Flow: Right Atrium

  • Right atrium --> tricuspid valve --> right ventricle

Heart Valve Blood Flow: Right Ventricle

  • Right ventricle --> pulmonary valve --> pulmonary arteries --> lungs

Heart Valve Blood Flow: Lungs

  • Lungs --> pulmonary veins --> left atrium --> bicuspid valve --> left ventricle --> aortic semilunar valve --> aorta --> systemic circulation

Valvular Pathologies:

Regurgitations (Insufficiency, Incompetency)

  • Valve does not close properly
  • Whistle sound is produced which creates a murmur

Stenosis

  • Valve does not open completely
  • Swish sound is produced

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