Cardiovascular Pharmacology Quiz
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Questions and Answers

What is the primary medical use of Minoxidil?

  • To treat hypertension
  • To relieve angina pectoris
  • To reduce ischemic heart disease
  • To stimulate hair growth (correct)

Which of the following lifestyle therapies is NOT recommended for managing hypertension?

  • Increased sodium intake (correct)
  • Alcohol cessation
  • Regular physical activity
  • Weight loss

What indicates unstable angina compared to stable angina?

  • Occurrence even at rest (correct)
  • Presence of sharp, stabbing pain
  • Occurrence only during physical activity
  • Worsening pain over time

What is a critical nursing consideration when measuring blood pressure?

<p>Utilizing a correct technique (A)</p> Signup and view all the answers

How long can Nitroglycerin sublingual tablets remain effective after opening the pack?

<p>1 month (D)</p> Signup and view all the answers

What is defined as a sustained systolic blood pressure greater than 140 mm Hg or a sustained diastolic blood pressure greater than 90 mm Hg?

<p>Hypertension (B)</p> Signup and view all the answers

Which drug class includes Hydrochlorothiazide and Furosemide?

<p>Diuretics (D)</p> Signup and view all the answers

Which type of blood pressure represents the pressure in the arteries when the heart is at rest?

<p>Diastolic blood pressure (A)</p> Signup and view all the answers

Which of the following is a potential side effect of Angiotensin-converting enzyme (ACE) inhibitors?

<p>Dry cough (D)</p> Signup and view all the answers

Which of these conditions is NOT classified as a common cardiovascular disease?

<p>Diabetes (B)</p> Signup and view all the answers

Which antihypertensive agent may cause leg edema as a side effect?

<p>Amlodipine (D)</p> Signup and view all the answers

Which lifestyle factor is NOT a risk factor for cardiovascular diseases?

<p>Regular exercise (A)</p> Signup and view all the answers

Which of the following antihypertensive agents is categorized under selective renin inhibitors?

<p>Aliskiren (A)</p> Signup and view all the answers

Flashcards

Hypertension and Cardiovascular Disease

Hypertension is a major risk factor for heart attacks and strokes, contributing to 40% of cases.

Direct-Acting Vasodilators in Hypertension

Direct-acting smooth muscle relaxants like hydralazine and minoxidil are not typically used as primary treatments for hypertension. Minoxidil, however, is used topically to stimulate hair growth in alopecia.

What is Angina Pectoris?

Angina pectoris is chest pain caused by reduced blood flow and oxygen supply to the heart. The more severe the oxygen deprivation, the more intense the pain.

Nitroglycerin for Angina

Sublingual nitroglycerin tablets are used to relax and dilate veins, improving blood flow to the heart. These tablets have a short shelf life, expiring one month after opening the container.

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Beta Blockers and Angina Types

Beta blockers help control excessive heart muscle activity. Stable angina worsens with exercise, while unstable angina occurs even at rest and is more dangerous.

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Hypertension

High blood pressure, defined as a sustained systolic blood pressure greater than 140 mm Hg or a diastolic blood pressure greater than 90 mm Hg.

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Congestive Heart Failure (CHF)

A condition where the heart doesn't pump blood efficiently, leading to fluid buildup in the lungs and body.

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Atherosclerosis

A narrowing of the arteries due to plaque buildup, often leading to chest pain, shortness of breath, and heart attack.

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Angina Pectoris

A type of chest pain caused by reduced blood flow to the heart muscle, often triggered by exertion.

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Adrenergic Agents

A group of medications used to treat high blood pressure by blocking the effects of the sympathetic nervous system.

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Diuretics

A group of medications used to treat high blood pressure by increasing urine output, thus lowering blood volume and pressure.

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Angiotensin II Receptor Blockers

A group of medications that relax blood vessels and reduce blood pressure by blocking the effects of angiotensin II.

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Calcium Channel Blockers

A group of medications that block calcium channels in blood vessels, causing relaxation and reducing blood pressure.

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Study Notes

Cardiovascular System

  • The cardiovascular system (CVS) includes the heart, arteries, arterioles, veins, venules, and capillaries.
  • The heart is a four-chambered pump (two atria, two ventricles).
  • Common cardiovascular diseases include hypertension, hyperlipidemia (atherosclerosis), angina pectoris (chest pain), congestive heart failure (CHF), myocardial infarction (coronary heart disease), and arrhythmia (irregular heartbeat).
  • Other cardiovascular diseases include congenital and rheumatic heart disease, and stroke.

Risk Factors of Cardiovascular Diseases

  • Risk factors for cardiovascular diseases include hypertension, hyperlipidemia, diabetes, obesity, high dietary salt intake, alcohol consumption, cigarette smoking, insufficient physical activity, and stress.

Blood Pressure

  • Blood pressure is the force of blood pushing against artery walls.
  • Normal systolic blood pressure is below 120 mmHg, and diastolic blood pressure is below 80 mmHg.
  • Systolic blood pressure is the pressure when the heart pumps blood.
  • Diastolic blood pressure is the pressure when the heart is at rest.

Hypertension

  • Hypertension is defined as sustained systolic blood pressure above 140 mmHg or sustained diastolic blood pressure above 90 mmHg.
  • Hypertension results from increased peripheral vascular arteriolar smooth muscle tone.

Antihypertensive Agents

  • Diuretics: Thiazide, loop, and potassium-sparing diuretics.
  • Adrenergic agents: Beta-blockers (propranolol, atenolol, metoprolol), alpha-blockers (prazosin, doxazosin, terazosin).
  • Angiotensin-converting enzyme (ACE) inhibitors: Enalapril, captopril, lisinopril. Side effect: dry cough and angioedema.
  • Angiotensin II receptor blockers (ARBs): Losartan, candesartan, irbesartan. Side effect: less dry cough and angioedema.
  • Calcium channel blockers: Verapamil, diltiazem, amlodipine, nifedipine. Side effect: leg edema.
  • Central sympatholytics: Clonidine, methyldopa. Used in pregnant patients.
  • Selective renin inhibitor: Aliskiren. Side effects: diarrhea, dry cough, and angioedema (especially at higher doses).
  • Vasodilators: Hydralazine, minoxidil. Not typically used as primary hypertension treatment but can be used to stimulate hair growth topically.

Nursing Considerations for Hypertension

  • High blood pressure increases the risk of ischemic heart disease and stroke. (40% attributed to HTN)
  • Nurses need to accurately measure blood pressure using proper technique and equipment.
  • Lifestyle changes (diet, exercise, stress reduction) are important.
  • Ongoing monitoring and management of anti-hypertensive treatment are crucial.

Angina Pectoris

  • Ischemia (decreased blood and oxygen supply) causes angina pectoris.
  • Nitroglycerin (sublingual tablets) relaxes blood vessels to relieve pain.
  • Nitroglycerin packs should be checked for expiry.
  • Stable angina is worsened by exertion, unstable angina occurs at rest.

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Description

Test your knowledge on cardiovascular pharmacology and hypertension management. This quiz covers essential medications, lifestyle therapies, and critical nursing considerations related to blood pressure and cardiovascular diseases. Perfect for nursing students and healthcare professionals.

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