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Cardiovascular Medications: Hydrochlorothiazide vs. Chlorthalidone

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Cardiovascular Medications: Hydrochlorothiazide vs. Chlorthalidone

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Questions and Answers

What is the main mechanism of action of Quinidine as an antiarrhythmic drug?

Binds to open and inactivated Na+ channels (correct)

Blocks Ca2+ channels

Inhibits K+ channels

Shortens phase 3 repolarization

How do Class IB antiarrhythmic drugs, like lidocaine and mexiletine, differ from Class IA drugs?

Block Ca2+ channels

Increase refractoriness

Shorten phase 3 repolarization (correct)

Contribute to negative inotropy

Which drug is used as an alternative for ventricular arrhythmias and may cause nausea, vomiting, and dyspepsia?

Procainamide

Quinidine

Mexiletine (correct)

Amiodarone

What are the typical CNS effects associated with the use of Lidocaine?

Drowsiness and agitation Signup and view all the answers

What is the A/E (adverse effect) associated with Quinidine known as 'cinchonism'?

Psychosis Signup and view all the answers

Which antiarrhythmic drug has mostly replaced Procainamide for electrical cardioversion or defibrillation in clinical practice?

Amiodarone Signup and view all the answers

What is the primary therapeutic use of Quinidine among patients with atherosclerotic heart disease or systolic heart failure?

Management of atrial tachyarrhythmias Signup and view all the answers

'VT storms' can be managed using which antiarrhythmic drug often used in combination with Amiodarone?

Lidocaine Signup and view all the answers

'Nystagmus' can be considered an early indicator of toxicity associated with which antiarrhythmic drug?

Lidocaine Signup and view all the answers

Among Class IB antiarrhythmic drugs, which one decreases the duration of the action potential?

Mexiletine Signup and view all the answers