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Cardiovascular Medications: Hydrochlorothiazide vs. Chlorthalidone
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Cardiovascular Medications: Hydrochlorothiazide vs. Chlorthalidone

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Questions and Answers

What is the main mechanism of action of Quinidine as an antiarrhythmic drug?

  • Binds to open and inactivated Na+ channels (correct)
  • Blocks Ca2+ channels
  • Inhibits K+ channels
  • Shortens phase 3 repolarization

    • How do Class IB antiarrhythmic drugs, like lidocaine and mexiletine, differ from Class IA drugs?

  • Block Ca2+ channels
  • Increase refractoriness
  • Shorten phase 3 repolarization (correct)
  • Contribute to negative inotropy

    • Which drug is used as an alternative for ventricular arrhythmias and may cause nausea, vomiting, and dyspepsia?

  • Procainamide
  • Quinidine
  • Mexiletine (correct)
  • Amiodarone

    • What are the typical CNS effects associated with the use of Lidocaine?

    <p>Drowsiness and agitation</p> Signup and view all the answers

    What is the A/E (adverse effect) associated with Quinidine known as 'cinchonism'?

    <p>Psychosis</p> Signup and view all the answers

    Which antiarrhythmic drug has mostly replaced Procainamide for electrical cardioversion or defibrillation in clinical practice?

    <p>Amiodarone</p> Signup and view all the answers

    What is the primary therapeutic use of Quinidine among patients with atherosclerotic heart disease or systolic heart failure?

    <p>Management of atrial tachyarrhythmias</p> Signup and view all the answers

    'VT storms' can be managed using which antiarrhythmic drug often used in combination with Amiodarone?

    <p>Lidocaine</p> Signup and view all the answers

    'Nystagmus' can be considered an early indicator of toxicity associated with which antiarrhythmic drug?

    <p>Lidocaine</p> Signup and view all the answers

    Among Class IB antiarrhythmic drugs, which one decreases the duration of the action potential?

    <p>Mexiletine</p> Signup and view all the answers

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