Cardiovascular Medications First-Line Therapy Guidelines

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Questions and Answers

Which class of antihypertensive agents is preferred as first-line therapy for stage 1 hypertension?

  • Beta blockers
  • Diuretics (correct)
  • ACE inhibitors
  • Calcium channel blockers

For individuals with Ischemic Heart Disease, what drug class is the first choice for stable angina?

  • ACE inhibitors
  • Beta blockers (correct)
  • Calcium channel blockers
  • Diuretics

In acute coronary syndrome, which two drug classes are recommended for treatment?

  • Beta blockers and ACE inhibitors (correct)
  • Thiazide diuretics and beta blockers
  • Diuretics and ARBs
  • Calcium channel blockers and loop diuretics

For individuals with Heart Failure, which two drug classes are recommended for asymptomatic individuals?

<p>ACE inhibitors and aldosterone blockers (D)</p> Signup and view all the answers

What is the targeted BP goal for patients with Diabetes Mellitus?

<p>130/80 (B)</p> Signup and view all the answers

Which combination of drug classes can lower the rate of recurrent stroke in individuals with Cerebrovascular Disease?

<p>ACE inhibitors and thiazide-type diuretics (C)</p> Signup and view all the answers

For individuals with Left Ventricular Hypertrophy, what is recommended among the following?

<p>Aggressive BP management and calcium channel blockers (B)</p> Signup and view all the answers

In cases of Chronic Kidney Disease, what is recommended for BP management?

<p>Aggressive management with ACE inhibitors and ARBs (B)</p> Signup and view all the answers

For patients with Obesity and Metabolic Syndrome, what is recommended?

<p>Lifestyle modifications and drug therapy for each component of metabolic syndrome (C)</p> Signup and view all the answers

Which drug classes are acceptable for treatment of individuals with any stage of hypertension?

<p>All classes of antihypertensive agents (D)</p> Signup and view all the answers

Which class of medication acts by inhibiting Dipeptidyl Peptidase-4 enzyme?

<p>Dipeptidyl Peptidase-4 Inhibitors (D)</p> Signup and view all the answers

Which medication promotes insulin secretion, suppresses glucagon, and slows gastric emptying?

<p>Exenatide (A)</p> Signup and view all the answers

In which condition should Pramlintide Acetate be avoided due to contraindications?

<p>Type 1 DM (A)</p> Signup and view all the answers

Which of the following medication can be prescribed as an injectable only?

<p>Pramlintide (A)</p> Signup and view all the answers

Among the listed adverse drug effects (ADE), which one is commonly associated with Dipeptidyl Peptidase-4 Inhibitors like Sitagliptin?

<p>Hypoglycemia (C)</p> Signup and view all the answers

What is the primary mechanism of action of Pramlintide Acetate?

<p>Regulation of appetite (A)</p> Signup and view all the answers

Which class of medication can be used either as monotherapy or in combination with Meformin and sulfonylureas?

<p>Dipeptidyl Peptidase-4 Inhibitors (B)</p> Signup and view all the answers

Which medication should be avoided in individuals with a history of pancreatitis?

<p>Exenatide (D)</p> Signup and view all the answers

What is a common adverse drug effect associated with Exenatide?

<p>UTIs (A)</p> Signup and view all the answers

For which type of diabetes is Pramlintide Acetate indicated to help regulate wide glycemic swings?

<p>Type 1 DM (B)</p> Signup and view all the answers

Which medication is specifically avoided in patients with history of pancreatitis?

<p>Sitagliptin (A)</p> Signup and view all the answers

What is the primary mechanism of action of Meglitinide Analogs like Repaglinide?

<p>Blocks ATP potassium channels on beta islet cells (C)</p> Signup and view all the answers

Which medication should be used cautiously in patients with renal dysfunction?

<p>Rosiglitazone (C)</p> Signup and view all the answers

In which condition is Metformin contraindicated?

<p>Type 1 Diabetes Mellitus (A)</p> Signup and view all the answers

Which medication is preferred for Black patients with or without Diabetes Mellitus?

<p>Thiazide diuretics (D)</p> Signup and view all the answers

What is the primary rationale behind the use of Alpha antagonists like tamsulosin for Benign Prostatic Hypertrophy (BPH)?

<p>Avoids increased cardiovascular mortality (B)</p> Signup and view all the answers

Which group of patients would most benefit from initial treatment with ACEIs, ARBs, thiazide diuretics, or CCBs?

<p>Hispanic patients (A)</p> Signup and view all the answers

What is the key purpose of using Sulfonylureas like glyburide or glimepiride when treating Diabetes Mellitus?

<p>Improve target cell insulin response (A)</p> Signup and view all the answers

Which drug is specifically avoided in chronic kidney disease for blood pressure management?

<p>Rosiglitazone (A)</p> Signup and view all the answers

What is the key benefit of Metformin in patients with Diabetes Mellitus?

<p>Doesn't cause hypoglycemia (C)</p> Signup and view all the answers

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