Cardiovascular Medications First-Line Therapy Guidelines
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Questions and Answers

Which class of antihypertensive agents is preferred as first-line therapy for stage 1 hypertension?

  • Beta blockers
  • Diuretics (correct)
  • ACE inhibitors
  • Calcium channel blockers
  • For individuals with Ischemic Heart Disease, what drug class is the first choice for stable angina?

  • ACE inhibitors
  • Beta blockers (correct)
  • Calcium channel blockers
  • Diuretics
  • In acute coronary syndrome, which two drug classes are recommended for treatment?

  • Beta blockers and ACE inhibitors (correct)
  • Thiazide diuretics and beta blockers
  • Diuretics and ARBs
  • Calcium channel blockers and loop diuretics
  • For individuals with Heart Failure, which two drug classes are recommended for asymptomatic individuals?

    <p>ACE inhibitors and aldosterone blockers</p> Signup and view all the answers

    What is the targeted BP goal for patients with Diabetes Mellitus?

    <p>130/80</p> Signup and view all the answers

    Which combination of drug classes can lower the rate of recurrent stroke in individuals with Cerebrovascular Disease?

    <p>ACE inhibitors and thiazide-type diuretics</p> Signup and view all the answers

    For individuals with Left Ventricular Hypertrophy, what is recommended among the following?

    <p>Aggressive BP management and calcium channel blockers</p> Signup and view all the answers

    In cases of Chronic Kidney Disease, what is recommended for BP management?

    <p>Aggressive management with ACE inhibitors and ARBs</p> Signup and view all the answers

    For patients with Obesity and Metabolic Syndrome, what is recommended?

    <p>Lifestyle modifications and drug therapy for each component of metabolic syndrome</p> Signup and view all the answers

    Which drug classes are acceptable for treatment of individuals with any stage of hypertension?

    <p>All classes of antihypertensive agents</p> Signup and view all the answers

    Which class of medication acts by inhibiting Dipeptidyl Peptidase-4 enzyme?

    <p>Dipeptidyl Peptidase-4 Inhibitors</p> Signup and view all the answers

    Which medication promotes insulin secretion, suppresses glucagon, and slows gastric emptying?

    <p>Exenatide</p> Signup and view all the answers

    In which condition should Pramlintide Acetate be avoided due to contraindications?

    <p>Type 1 DM</p> Signup and view all the answers

    Which of the following medication can be prescribed as an injectable only?

    <p>Pramlintide</p> Signup and view all the answers

    Among the listed adverse drug effects (ADE), which one is commonly associated with Dipeptidyl Peptidase-4 Inhibitors like Sitagliptin?

    <p>Hypoglycemia</p> Signup and view all the answers

    What is the primary mechanism of action of Pramlintide Acetate?

    <p>Regulation of appetite</p> Signup and view all the answers

    Which class of medication can be used either as monotherapy or in combination with Meformin and sulfonylureas?

    <p>Dipeptidyl Peptidase-4 Inhibitors</p> Signup and view all the answers

    Which medication should be avoided in individuals with a history of pancreatitis?

    <p>Exenatide</p> Signup and view all the answers

    What is a common adverse drug effect associated with Exenatide?

    <p>UTIs</p> Signup and view all the answers

    For which type of diabetes is Pramlintide Acetate indicated to help regulate wide glycemic swings?

    <p>Type 1 DM</p> Signup and view all the answers

    Which medication is specifically avoided in patients with history of pancreatitis?

    <p>Sitagliptin</p> Signup and view all the answers

    What is the primary mechanism of action of Meglitinide Analogs like Repaglinide?

    <p>Blocks ATP potassium channels on beta islet cells</p> Signup and view all the answers

    Which medication should be used cautiously in patients with renal dysfunction?

    <p>Rosiglitazone</p> Signup and view all the answers

    In which condition is Metformin contraindicated?

    <p>Type 1 Diabetes Mellitus</p> Signup and view all the answers

    Which medication is preferred for Black patients with or without Diabetes Mellitus?

    <p>Thiazide diuretics</p> Signup and view all the answers

    What is the primary rationale behind the use of Alpha antagonists like tamsulosin for Benign Prostatic Hypertrophy (BPH)?

    <p>Avoids increased cardiovascular mortality</p> Signup and view all the answers

    Which group of patients would most benefit from initial treatment with ACEIs, ARBs, thiazide diuretics, or CCBs?

    <p>Hispanic patients</p> Signup and view all the answers

    What is the key purpose of using Sulfonylureas like glyburide or glimepiride when treating Diabetes Mellitus?

    <p>Improve target cell insulin response</p> Signup and view all the answers

    Which drug is specifically avoided in chronic kidney disease for blood pressure management?

    <p>Rosiglitazone</p> Signup and view all the answers

    What is the key benefit of Metformin in patients with Diabetes Mellitus?

    <p>Doesn't cause hypoglycemia</p> Signup and view all the answers

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