Cardiovascular Disease Risk Factors Quiz

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Questions and Answers

Which of the following is considered one drink equivalent?

  • 500 mL of beer
  • 100 mL of 40-proof distilled spirits
  • 45 mL of 80-proof distilled spirits (correct)
  • 200 mL of wine at 10% alcohol content

What is recommended as a first-line antihypertensive agent for most patients?

  • Nitrates
  • Calcium channel blockers (correct)
  • Diuretics
  • Beta-blockers

What is the approximate volume of wine that is equivalent to one drink?

  • 100 mL at 8% alcohol content
  • 75 mL at 6% alcohol content
  • 150 mL at 12% alcohol content (correct)
  • 200 mL at 15% alcohol content

What lifestyle modification is appropriate for patients with elevated BP?

<p>Dietary changes (B)</p> Signup and view all the answers

When is combination drug therapy recommended for hypertension treatment?

<p>Stage 2 hypertension (D)</p> Signup and view all the answers

Which of the following is NOT considered a first-line antihypertensive agent for most patients?

<p>Beta-blockers (D)</p> Signup and view all the answers

What is a key benefit of angiotensin-converting enzyme inhibitors (ACEI) in patients with heart failure with reduced ejection fraction (HFrEF)?

<p>Improving cardiovascular mortality and morbidity (D)</p> Signup and view all the answers

What effect does an ACEI have on bradykinin?

<p>It enhances the BP-lowering effects of an ACEI (D)</p> Signup and view all the answers

Which vasodilating substance is stimulated by the blockage of ACE by ACEIs?

<p>Prostaglandin E2 (D)</p> Signup and view all the answers

What side effect is associated with increased bradykinin levels due to ACEI therapy?

<p>Dry cough (D)</p> Signup and view all the answers

In which condition does ACEI therapy help prevent or regress left ventricular hypertrophy (LVH)?

<p>Coronary heart disease (CHD) (B)</p> Signup and view all the answers

Which patient population would benefit from an ACEI regimen combined with a thiazide for recurrent stroke prevention?

<p>Patients with diabetes and hypertension (D)</p> Signup and view all the answers

What is a notable difference between ARB therapy and ACEI therapy?

<p>ARB therapy directly blocks the AT1 receptor, while ACEI therapy blocks the breakdown of bradykinin. (D)</p> Signup and view all the answers

What can be a consequence of using both an ACEI and an ARB simultaneously?

<p>Higher risk of renal dysfunction and hypotension (A)</p> Signup and view all the answers

Why should the starting dose of ARB be reduced in some patients?

<p>Due to risks of hypotension (A)</p> Signup and view all the answers

Which condition would not be a contraindication for using ARB therapy?

<p>Volume depletion (B)</p> Signup and view all the answers

Why is the combination of ACEI with ARB not recommended?

<p>It has no additional CV event-lowering benefits. (A)</p> Signup and view all the answers

Which effect is NOT associated with ARB therapy?

<p>Vasodilation (C)</p> Signup and view all the answers

What is responsible for the initial drop in blood pressure seen when diuretics are first started?

<p>Initial diuresis (A)</p> Signup and view all the answers

Why do diuretics need to be dosed in the morning if given once daily?

<p>To minimize risk of nocturnal diuresis (B)</p> Signup and view all the answers

What is responsible for the chronic antihypertensive effects of diuretics?

<p>Reduction in PVR (C)</p> Signup and view all the answers

Which side effect is rare with chronic use of thiazides, potassium-sparing diuretics, and aldosterone antagonists?

<p>Dizziness (B)</p> Signup and view all the answers

What side effect is more pronounced with loop diuretics compared to thiazides?

<p>Hypomagnesemia (C)</p> Signup and view all the answers

Which electrolyte imbalance may cause muscle fatigue or cramps?

<p>Hypomagnesemia (D)</p> Signup and view all the answers

What is a notable side effect of dihydropyridines?

<p>Headache (D)</p> Signup and view all the answers

Which non-dihydropyridine CCB is associated with constipation as a side effect?

<p>Verapamil (C)</p> Signup and view all the answers

Why is immediate-release nifedipine not recommended for the treatment of hypertension?

<p>It results in flushing and peripheral edema (B)</p> Signup and view all the answers

Which side effect is more common with all dihydropyridines compared to non-dihydropyridines?

<p>Dizziness (C)</p> Signup and view all the answers

What cardiac conduction abnormalities can be caused by nondihydropyridine CCBs?

<p>AV block (D)</p> Signup and view all the answers

Which medications may have increased serum concentrations due to interactions with verapamil and diltiazem?

<p>All of the above (D)</p> Signup and view all the answers

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