18 Questions
What is the main factor that determines the diffusion potential across a membrane?
Concentration gradients of ions
What is the significance of the Goldman equation in determining the membrane potential?
It helps determine the voltage of the membrane potential
What is the effect of a positive ion concentration gradient from inside to outside on the membrane potential?
It creates electronegativity inside the membrane
What is the resting membrane potential (RMP)?
Electrical potential existing across the cell membrane under resting state
What is the Nernst potential for K+ calculated as?
-94mV
What is the polarity of the electrical charge required to block further net diffusion of Na+ ions in a normal mammalian nerve fiber?
Positivity inside the membrane
What is the Nernst potential for Na+ calculated as?
+61mV
What undergoes rapid changes during nerve impulse transmission?
Permeability of Na+ and K+
According to the Goldman equation, what is the contribution of K+ to the resting membrane potential?
-94mV
What is the net resting membrane potential according to the Goldman equation?
-90mV
What is the contribution of Na+ to the resting membrane potential according to the Goldman equation?
+8mV
What is the contribution of the Na+-K+ pump to the resting membrane potential?
-4mV
What is the temperature at which the Nernst equation is used to calculate the Nernst potential?
98.6°F
What is the Nernst potential for K+ calculated using the Nernst equation?
-94mV
What happens to the net diffusion of Na+ ions if the membrane is only permeable to Na+ ions?
Net diffusion occurs from outside to inside
What is the result of the net diffusion of Na+ from outside to inside?
Creates positivity inside the membrane
What is the Nernst equation used for?
To calculate the Nernst potential for a single ion
What determines the magnitude of the Nernst potential?
The ratio of the concentrations of a particular ion on the two sides of the membrane
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