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Questions and Answers
What is stroke volume (SV)?
What is stroke volume (SV)?
Which equation correctly represents cardiac output (CO)?
Which equation correctly represents cardiac output (CO)?
What effect does digoxin have on stroke volume?
What effect does digoxin have on stroke volume?
How does increased viscosity of blood typically affect blood flow resistance?
How does increased viscosity of blood typically affect blood flow resistance?
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What impact does stroke volume have on blood pressure?
What impact does stroke volume have on blood pressure?
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What percentage of blood is normally ejected from the ventricle during systole?
What percentage of blood is normally ejected from the ventricle during systole?
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Which condition would most likely result in a low ejection fraction?
Which condition would most likely result in a low ejection fraction?
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What happens to the pressure gradient required to maintain blood flow if the resistance doubles?
What happens to the pressure gradient required to maintain blood flow if the resistance doubles?
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How does increased body weight affect blood flow resistance?
How does increased body weight affect blood flow resistance?
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What is the role of viscosity in blood flow?
What is the role of viscosity in blood flow?
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What defines turbulent flow in blood vessels?
What defines turbulent flow in blood vessels?
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When does the S4 heart sound typically occur?
When does the S4 heart sound typically occur?
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What physiological condition is associated with an S3 heart sound in adults?
What physiological condition is associated with an S3 heart sound in adults?
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What effect does sympathetic activation primarily have on systemic vascular resistance (SVR)?
What effect does sympathetic activation primarily have on systemic vascular resistance (SVR)?
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Which of the following substances is NOT involved in the contraction of vascular smooth muscle?
Which of the following substances is NOT involved in the contraction of vascular smooth muscle?
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Which factor contributes to an increase in cardiac output under sympathetic activation?
Which factor contributes to an increase in cardiac output under sympathetic activation?
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What equation represents perfusion pressure?
What equation represents perfusion pressure?
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Which neurohumoral factor primarily promotes sodium retention and consequently increases blood volume?
Which neurohumoral factor primarily promotes sodium retention and consequently increases blood volume?
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What effect does vasovagal syncope have on blood flow to the brain?
What effect does vasovagal syncope have on blood flow to the brain?
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Which of the following local factors is associated with vasodilation?
Which of the following local factors is associated with vasodilation?
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How does an increase in stroke volume affect blood pressure?
How does an increase in stroke volume affect blood pressure?
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What primarily affects the stroke volume (SV) during periods of increased heart rate?
What primarily affects the stroke volume (SV) during periods of increased heart rate?
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Which factor is likely to lead to a decrease in blood pressure?
Which factor is likely to lead to a decrease in blood pressure?
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How does increased blood viscosity typically impact blood flow resistance?
How does increased blood viscosity typically impact blood flow resistance?
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Which of the following would NOT typically increase stroke volume?
Which of the following would NOT typically increase stroke volume?
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What is the primary consequence of utilizing digoxin in heart conditions concerning stroke volume?
What is the primary consequence of utilizing digoxin in heart conditions concerning stroke volume?
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What percentage of blood ejected from the ventricle during systole is considered normal?
What percentage of blood ejected from the ventricle during systole is considered normal?
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What happens to the required pressure gradient if blood flow resistance is doubled?
What happens to the required pressure gradient if blood flow resistance is doubled?
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How does increased body weight influence blood flow resistance?
How does increased body weight influence blood flow resistance?
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Which factor is NOT typically associated with turbulent flow in blood vessels?
Which factor is NOT typically associated with turbulent flow in blood vessels?
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Which heart sound is associated with late diastole during atrial contraction?
Which heart sound is associated with late diastole during atrial contraction?
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What does a low ejection fraction typically indicate?
What does a low ejection fraction typically indicate?
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What kind of flow occurs when laminar flow is disrupted by high velocities?
What kind of flow occurs when laminar flow is disrupted by high velocities?
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What is the relationship between viscosity and blood flow resistance?
What is the relationship between viscosity and blood flow resistance?
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What is the primary effect of sympathetic activation on systemic vascular resistance (SVR)?
What is the primary effect of sympathetic activation on systemic vascular resistance (SVR)?
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Which local factor is primarily associated with vasodilation in blood vessels?
Which local factor is primarily associated with vasodilation in blood vessels?
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How does increased blood volume through renal receptor activation affect cardiac preload?
How does increased blood volume through renal receptor activation affect cardiac preload?
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What is the main action of the renin-angiotensin-aldosterone system when activated?
What is the main action of the renin-angiotensin-aldosterone system when activated?
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What effect does bradykinin have on blood vessels?
What effect does bradykinin have on blood vessels?
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In the context of blood pressure regulation, which effect do vasovagal syncope episodes have?
In the context of blood pressure regulation, which effect do vasovagal syncope episodes have?
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Which neurotransmitter is primarily associated with increasing cardiac output during sympathetic activation?
Which neurotransmitter is primarily associated with increasing cardiac output during sympathetic activation?
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Which factor is likely to lead to increased blood flow resistance?
Which factor is likely to lead to increased blood flow resistance?
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During which phase of the cardiac cycle does the left ventricular pressure increase without a change in volume?
During which phase of the cardiac cycle does the left ventricular pressure increase without a change in volume?
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What is the primary factor that affects the left ventricular end diastolic volume (LVEDV)?
What is the primary factor that affects the left ventricular end diastolic volume (LVEDV)?
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What occurs during the rapid ejection phase of the cardiac cycle?
What occurs during the rapid ejection phase of the cardiac cycle?
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Which statement best describes the relationship between blood viscosity and resistance to blood flow?
Which statement best describes the relationship between blood viscosity and resistance to blood flow?
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What is the consequence of increased resistance on blood flow during the cardiac cycle?
What is the consequence of increased resistance on blood flow during the cardiac cycle?
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What does a high ejection fraction typically indicate regarding ventricular function?
What does a high ejection fraction typically indicate regarding ventricular function?
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Which of the following statements about blood viscosity is correct?
Which of the following statements about blood viscosity is correct?
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Which scenario would most likely lead to an increase in blood flow resistance?
Which scenario would most likely lead to an increase in blood flow resistance?
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What condition is associated with a significant reduction in ejection fraction?
What condition is associated with a significant reduction in ejection fraction?
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In terms of maintaining the same flow, what happens when the resistance in the system doubles?
In terms of maintaining the same flow, what happens when the resistance in the system doubles?
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Which of the following correctly describes how increased body weight affects blood flow resistance?
Which of the following correctly describes how increased body weight affects blood flow resistance?
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What characterizes turbulent flow in blood vessels?
What characterizes turbulent flow in blood vessels?
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During which cardiac event does atrial contraction primarily contribute to ventricular filling?
During which cardiac event does atrial contraction primarily contribute to ventricular filling?
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What primarily influences the dilation of blood vessels?
What primarily influences the dilation of blood vessels?
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Which factor contributes most to an increase in systemic vascular resistance (SVR)?
Which factor contributes most to an increase in systemic vascular resistance (SVR)?
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Which hormone primarily promotes sodium retention to increase blood volume?
Which hormone primarily promotes sodium retention to increase blood volume?
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In which condition would an increase in blood flow resistance most likely occur?
In which condition would an increase in blood flow resistance most likely occur?
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Which scenario would lead to a decrease in cardiac output?
Which scenario would lead to a decrease in cardiac output?
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Which of the following factors is associated with contraction of vascular smooth muscle?
Which of the following factors is associated with contraction of vascular smooth muscle?
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What is the key consequence of an increase in systemic vascular resistance?
What is the key consequence of an increase in systemic vascular resistance?
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Which factor is unlikely to directly affect blood pressure?
Which factor is unlikely to directly affect blood pressure?
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How does increased blood volume influence stroke volume?
How does increased blood volume influence stroke volume?
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What effect does increased stroke volume have on blood pressure, assuming heart rate remains constant?
What effect does increased stroke volume have on blood pressure, assuming heart rate remains constant?
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Under what condition would blood viscosity most likely increase, affecting blood flow resistance?
Under what condition would blood viscosity most likely increase, affecting blood flow resistance?
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What relationship exists between stroke volume and cardiac output when heart rate is reduced?
What relationship exists between stroke volume and cardiac output when heart rate is reduced?
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Which factor is least likely to directly reduce blood flow resistance in vessels?
Which factor is least likely to directly reduce blood flow resistance in vessels?
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Which factor can decrease stroke volume under physical stress conditions?
Which factor can decrease stroke volume under physical stress conditions?
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Which physiological effect is primarily caused by an increase in blood viscosity?
Which physiological effect is primarily caused by an increase in blood viscosity?
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When blood flow resistance increases due to increased viscosity, what compensatory mechanism is most affected?
When blood flow resistance increases due to increased viscosity, what compensatory mechanism is most affected?
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In the context of heart failure, which aspect related to stroke volume is most critical to monitor?
In the context of heart failure, which aspect related to stroke volume is most critical to monitor?
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How does a decrease in stroke volume influence the resistance encountered in the vascular system?
How does a decrease in stroke volume influence the resistance encountered in the vascular system?
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What impact does digoxin have on stroke volume when considering its mechanism of action?
What impact does digoxin have on stroke volume when considering its mechanism of action?
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What does a decrease in the end-diastolic volume (EDV) typically indicate about stroke volume (SV)?
What does a decrease in the end-diastolic volume (EDV) typically indicate about stroke volume (SV)?
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How is stroke volume (SV) primarily affected during increased blood viscosity?
How is stroke volume (SV) primarily affected during increased blood viscosity?
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In what situation would you expect an increase in blood pressure regarding stroke volume?
In what situation would you expect an increase in blood pressure regarding stroke volume?
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What effect does high blood flow resistance generally have on blood pressure?
What effect does high blood flow resistance generally have on blood pressure?
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Which of the following conditions is likely to decrease stroke volume?
Which of the following conditions is likely to decrease stroke volume?
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Which factor does NOT typically contribute to increased blood viscosity?
Which factor does NOT typically contribute to increased blood viscosity?
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How would an increase in stroke volume directly affect the workload of the heart?
How would an increase in stroke volume directly affect the workload of the heart?
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What primarily regulates the stroke volume in response to increased venous return?
What primarily regulates the stroke volume in response to increased venous return?
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What happens to systemic blood pressure if stroke volume is consistently below normal levels?
What happens to systemic blood pressure if stroke volume is consistently below normal levels?
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What is the likely effect on cardiovascular function with a sudden increase in blood viscosity?
What is the likely effect on cardiovascular function with a sudden increase in blood viscosity?
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Study Notes
Cardiac Conduction System
- Pacemaker cells initiate heartbeat; "funny" sodium channels (HCN) cause slow depolarization.
- L-type calcium channels trigger depolarization.
- Action potential phases in cardiac contractile cells (myocardial cells) are detailed.
- ECG correlations exist with specific intervals (PR, QT).
- Depolarization propagates through ventricular myocytes via gap junctions.
- Temperature affects cardiac electrophysiology.
- Gas stimulates adenylyl cyclase.
Cardiac Cycle
- Systole (ventricular contraction) and diastole (ventricular relaxation) are key phases.
- Events like ejection and filling of the heart occur during these phases.
- Normal ranges for end-diastolic volume (EDV) and end-systolic volume (ESV) exist.
- The cardiac cycle involves early diastolic filling phase.
- Atrial systole precedes ventricular systole.
Cardiac Output (CO) and Stroke Volume (SV)
- Cardiac output (CO) is the volume of blood pumped per minute.
- Stroke volume (SV) is the volume of blood pumped per beat.
- Relationship between CO and SV is crucial.
- Stroke volume is dependent upon EDV and ESV.
- SV is calculated by subtracting end-systolic volume (ESV) from end-diastolic volume (EDV).
Key Pressures and Volumes Summary
- End-diastolic volume (EDV), end-systolic volume (ESV), and other volumes are summarised with corresponding pressures.
- Central Venous Pressure (CVP) is negligible (0 mmHg).
Blood Pressure Determinants
- Arterial pressure is the driving force for blood flow.
- Main determinants of arterial pressure include: sympathetic activity, heart rate (HR), stroke volume (SV), and vascular resistance (SVR).
- Local factors affecting blood pressure include PGE, PGI2, PGE2, and NO (nitric oxide).
Effects of Sympathetic Activation
- Sympathetic activation increases heart rate (HR) and stroke volume (SV).
- 8-Adrenergic receptors are involved.
ECG Correlation and Phases
- QRS complex is described in detail during depolarization phases.
- Q wave - initial downward deflection.
- Sharp upward deflection (R wave)
- Return to baseline (ST segment)
- Final ventricular depolarization.
Additional Notes
- Mean vector and instantaneous vectors relating to electricity (electrical dipoles) are described.
- Turbulent vs laminar blood flow is mentioned briefly.
- Atrial systole occurs before ventricular systole.
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Description
Test your knowledge on the cardiac conduction system, the phases of the cardiac cycle, and key measurements like cardiac output and stroke volume. This quiz covers essential concepts related to heart function and the events that occur during contraction and relaxation.