Podcast
Questions and Answers
How does heart muscle differ from skeletal muscle in terms of stimulation and contraction?
How does heart muscle differ from skeletal muscle in terms of stimulation and contraction?
- Heart muscle contraction is significantly faster than skeletal muscle contraction.
- Heart muscle requires direct nerve stimulation for each contraction, unlike skeletal muscle.
- Heart muscle has a short refractory period compared to the long refractory period of skeletal muscle.
- Heart muscle is self-excitable (automaticity) and contracts as a unit, whereas skeletal muscle requires nerve stimulation. (correct)
Why is the long absolute refractory period in cardiac muscle important?
Why is the long absolute refractory period in cardiac muscle important?
- It speeds up the rate of contraction in the heart.
- It prevents tetanus, ensuring the heart relaxes between contractions. (correct)
- It allows the heart to contract more forcefully.
- It makes the heart muscle more sensitive to nerve stimulation.
What is the primary function of the sinoatrial (SA) node in the heart?
What is the primary function of the sinoatrial (SA) node in the heart?
- To carry the impulse to the heart apex and ventricular walls.
- To generate impulses and set the pace for the heart. (correct)
- To delay the impulse from the atria to the ventricles.
- To carry the impulse towards the apex of the heart.
What role does the atrioventricular (AV) node play in the cardiac cycle?
What role does the atrioventricular (AV) node play in the cardiac cycle?
Which of the following accurately describes the sequence of impulse conduction after it leaves the AV node?
Which of the following accurately describes the sequence of impulse conduction after it leaves the AV node?
What is a key characteristic of autorhythmic cells that distinguishes them from other cardiac cells?
What is a key characteristic of autorhythmic cells that distinguishes them from other cardiac cells?
Which ion is primarily responsible for the rising phase of the action potential in autorhythmic cells?
Which ion is primarily responsible for the rising phase of the action potential in autorhythmic cells?
During which phase of the cardiac action potential does rapid depolarization occur?
During which phase of the cardiac action potential does rapid depolarization occur?
What ionic movement is primarily associated with Phase 1 (early repolarization) of the cardiac action potential?
What ionic movement is primarily associated with Phase 1 (early repolarization) of the cardiac action potential?
What is the primary ionic basis for the plateau phase (Phase 2) of the cardiac action potential?
What is the primary ionic basis for the plateau phase (Phase 2) of the cardiac action potential?
Which ionic movement is predominantly responsible for the rapid repolarization phase (Phase 3) of the cardiac action potential?
Which ionic movement is predominantly responsible for the rapid repolarization phase (Phase 3) of the cardiac action potential?
What does the QRS complex on an electrocardiogram (ECG) represent in relation to the cardiac action potential?
What does the QRS complex on an electrocardiogram (ECG) represent in relation to the cardiac action potential?
What part of the electrocardiogram (ECG) relates to the repolarization phase of the action potential?
What part of the electrocardiogram (ECG) relates to the repolarization phase of the action potential?
What is the typical range for the number of action potentials generated per minute in the heart, under normal conditions?
What is the typical range for the number of action potentials generated per minute in the heart, under normal conditions?
How does the sympathetic nervous system influence cardiac function?
How does the sympathetic nervous system influence cardiac function?
Which of the following describes the effect of the parasympathetic nervous system on heart function?
Which of the following describes the effect of the parasympathetic nervous system on heart function?
What is a key limitation of the nervous system's ability to influence cardiac action potentials?
What is a key limitation of the nervous system's ability to influence cardiac action potentials?
What is the primary role of calcium channels open as shown in the diagram?
What is the primary role of calcium channels open as shown in the diagram?
How would the cardiac cycle be affected if the AV node was damaged?
How would the cardiac cycle be affected if the AV node was damaged?
The normal resting membrane potential is around -80mV, but the action potential from the diagram goes significantly higher, up to +40mV. Where does that extra +120mV potential come from?
The normal resting membrane potential is around -80mV, but the action potential from the diagram goes significantly higher, up to +40mV. Where does that extra +120mV potential come from?
Heart muscle is stimulated by nerves and is ______ (automaticity).
Heart muscle is stimulated by nerves and is ______ (automaticity).
Heart muscle contracts as a ______, ensuring coordinated pumping action.
Heart muscle contracts as a ______, ensuring coordinated pumping action.
Cardiac muscle has a long (250 ms) absolute ______ period, preventing tetanus.
Cardiac muscle has a long (250 ms) absolute ______ period, preventing tetanus.
The ______ node generates impulses at approximately 75 times per minute.
The ______ node generates impulses at approximately 75 times per minute.
The Atrioventricular (AV) node delays the impulse approximately ______ seconds.
The Atrioventricular (AV) node delays the impulse approximately ______ seconds.
Impulses pass from atria to ventricles via the ______ of His.
Impulses pass from atria to ventricles via the ______ of His.
The Bundle of His splits into two pathways in the interventricular septum called ______.
The Bundle of His splits into two pathways in the interventricular septum called ______.
[Blank] carry the impulse to the heart apex and ventricular walls.
[Blank] carry the impulse to the heart apex and ventricular walls.
[Blank] cells initiate action potentials in the heart.
[Blank] cells initiate action potentials in the heart.
The unstable resting potentials in autorhythmic cells are called ______ potentials.
The unstable resting potentials in autorhythmic cells are called ______ potentials.
Autorhythmic cells use ______ influx (rather than sodium) for the rising phase of the action potential.
Autorhythmic cells use ______ influx (rather than sodium) for the rising phase of the action potential.
The time course of the intracellular action potential has been superimposed on the ______.
The time course of the intracellular action potential has been superimposed on the ______.
The ______ phase of action potential coincides with the QRS complex on an ECG.
The ______ phase of action potential coincides with the QRS complex on an ECG.
The repolarization phase of the action potential coincides with the ______ wave on an ECG.
The repolarization phase of the action potential coincides with the ______ wave on an ECG.
The nervous system ______ elicits cardiac action potentials; this can only happen via the SA node.
The nervous system ______ elicits cardiac action potentials; this can only happen via the SA node.
Heart is ______ by the sympathetic cardioacceleratory centre.
Heart is ______ by the sympathetic cardioacceleratory centre.
Heart is ______ by the parasympathetic cardioinhibitory centre.
Heart is ______ by the parasympathetic cardioinhibitory centre.
Phase 2 of the cardiac cycle is also known as the ______.
Phase 2 of the cardiac cycle is also known as the ______.
Phase 3, also known as the ______, is identified by the efflux of potassium ions.
Phase 3, also known as the ______, is identified by the efflux of potassium ions.
Because the vagus nerve is associated with ______ responses, a problem would result with the heart slowing down too much.
Because the vagus nerve is associated with ______ responses, a problem would result with the heart slowing down too much.
Flashcards
Heart Muscle Characteristics
Heart Muscle Characteristics
Heart muscle is stimulated by nerves/self-excitable and has a long refractory period.
Automaticity
Automaticity
The heart's ability to initiate its own electrical impulses.
Sinoatrial (SA) node
Sinoatrial (SA) node
Generates impulses about 75 times per minute.
Atrioventricular (AV) node
Atrioventricular (AV) node
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Bundle branches
Bundle branches
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Purkinje fibers
Purkinje fibers
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Autorhythmic cells
Autorhythmic cells
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Pacemaker potentials
Pacemaker potentials
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Autorhythmic Action Potential
Autorhythmic Action Potential
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Cardiac AP Phase 0
Cardiac AP Phase 0
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Cardiac AP Phase 1
Cardiac AP Phase 1
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Cardiac AP Phase 2
Cardiac AP Phase 2
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Cardiac AP Phase 3
Cardiac AP Phase 3
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Cardiac AP Phase 4
Cardiac AP Phase 4
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Intracellular Action Potential
Intracellular Action Potential
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Action Potential Depolarization
Action Potential Depolarization
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Action Potential Repolarization
Action Potential Repolarization
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Heart Stimulation
Heart Stimulation
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Heart Inhibition
Heart Inhibition
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Cardiac Action Potentials
Cardiac Action Potentials
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Resting Potential
Resting Potential
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Study Notes
- Cardiac physiology covers the cardiac action potential.
Cardiac Muscle Contraction
- Heart muscle is stimulated by nerves, and is self-excitable, known as automaticity.
- Cardiac muscle contracts as a unit.
- It has a long absolute refractory period of 250 ms.
- Cardiac muscle contraction is similar to skeletal muscle contraction.
Heart Physiology: Sequence of Excitation
- The sinoatrial (SA) node generates impulses about 75 times per minute.
- The atrioventricular (AV) node delays the impulse approximately 0.1 second.
- Impulses pass from the atria to the ventricles via the bundle of His.
- The bundle of His splits into two pathways in the interventricular septum, which are the bundle branches.
- Bundle branches carry the impulse toward the apex of the heart.
- Purkinje fibers carry the impulse to the heart apex and ventricular walls.
Heart Physiology: Intrinsic Conduction System
- Autorhythmic cells initiate action potentials.
- They have unstable resting potentials called pacemaker potentials.
- Calcium influx, rather than sodium, is used for the rising phase of the action potential in autorhythmic cells.
Phases of the Cardiac Action Potential
- Phase 0 is depolarization.
- Phase 1 is the early repolarization phase.
- Phase 2 is the plateau phase.
- Phase 3 is the rapid repolarization phase.
ECG and Action Potential
- The intracellular action potential's time course has been superimposed on the electrocardiogram (ECG).
- The depolarization phase of the action potential coincides with the QRS complex on the ECG.
- Repolarization of the action potential coincides with the T wave on the ECG.
Autonomic Control
- Typically, about 75-80 action potentials are generated per minute.
- This can be regulated externally:
- The heart is stimulated by the sympathetic cardioacceleratory center.
- The heart is inhibited by the parasympathetic cardioinhibitory center.
- The nervous system is unable to elicit cardiac action potentials, only the sinoatrial node can.
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