cardiac physiology Q2.

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Questions and Answers

what links cardiac muscle together?

intercalated discs link muscle cell together and contain desmosomes and gap junction.

what's the function of desmosomes?

hold muscle cells together tightly.

what's the function of gap junction in heart muscle cells?

allow passage of action potential from cell to the next-allow cardiac muscle cell to function as a (syncytium).

what separates atria from ventricles?

<p>fibrous tissue that surround the 2 AV valve openings.</p> Signup and view all the answers

what's the function of the fibrous tissue seats the cardiac valve?

<p>they lack gap junctions and provide a border to (electrically) isolates atria from ventricles.</p> Signup and view all the answers

when the resting potential is accomplished?

<p>when the inside of the cell is negative relative to the outside of the cell.</p> Signup and view all the answers

what r the ions that contribute to the membrane potential?

<p>Na+,K+,Ca++</p> Signup and view all the answers

what's TMP?

<p>trans membrane potential which is the electrical potential difference between the inside and outside of the cell. +ve into cell -ev out of the cell</p> Signup and view all the answers

what r the 2 main forces that drive ions across cell membrane?

<p>chemical potential: an ion move down its conc gradient. electrical potential: an ion move away from ions of like charge.</p> Signup and view all the answers

proprieties of cardiac ions channels?

<p>1- selectivity 2- time-dependence 3- voltage-sensitive gating</p> Signup and view all the answers

Flashcards

Intercalated discs

Structures that connect cardiac muscle cells, containing desmosomes and gap junctions.

Desmosomes function

Hold cardiac muscle cells together tightly, preventing them from pulling apart during contraction.

Gap junctions function (heart)

Allow electrical signals to pass rapidly from one cardiac muscle cell to the next, enabling coordinated contraction.

Atrial-Ventricular (AV) separation

The fibrous tissue surrounding AV valve openings electrically isolates the atria from the ventricles.

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Resting Membrane Potential (RMP)

The inside of the cell is negative compared to the outside.

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Membrane Potential Ions

Sodium (Na+), Potassium (K+), and Calcium (Ca++) contribute to the electrical potential across the membrane.

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Transmembrane Potential (TMP)

The electrical potential difference between the inside and outside of a cell.

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Driving forces across membrane

"Chemical potential" (concentration gradient) and "Electrical potential" (charge difference) drive ions across cell membranes.

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Cardiac Ion Channel Properties

These channels exhibit selectivity (only let certain ions through), time dependence (open and close at specific times), and voltage sensitivity (gate opening depends on membrane potential).

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Cardiac Muscle Syncytium

Cardiac cells can function as a coordinated unit due to rapid communication between cells by the gap junctions.

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