Cannabis and Substance Withdrawal Strategies
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Questions and Answers

What is the role of CB1 receptors in the central nervous system?

  • They synthesize endocannabinoids in advance.
  • They are responsible for neuroprotection.
  • They improve inflammation when activated.
  • They influence memory, motor coordination, and attention. (correct)

    • Which of the following statements about endocannabinoids is true?

  • They are exclusively full agonists at cannabinoid receptors.
  • They inhibit the release of neurotransmitters like GABA and glutamate. (correct)
  • Anandamide acts solely as an antagonist at CB2 receptors.
  • Endocannabinoids are stored and released in advance.

    • What factor does NOT influence the absorption of THC when cannabis is inhaled?

  • Duration in the lungs
  • Depth of inhalation
  • Amount of THC
  • Type of marijuana used (correct)

    • Which endocannabinoid acts as a full agonist at both CB1 and CB2 receptors?

    <p>2-arachidonoyl glycerol (2-AG)</p> Signup and view all the answers

    Which psychotherapeutic strategy focuses on altering the thought patterns and behaviors associated with substance withdrawal?

    <p>Cognitive-behavioral therapy</p> Signup and view all the answers

    What type of medication is Bupropion classified as?

    <p>Dopaminergic antidepressant</p> Signup and view all the answers

    Which of the following is NOT listed as a medication used for managing withdrawal from substances?

    <p>Sertraline</p> Signup and view all the answers

    Which intervention strategy involves providing rewards for achieving substance cessation goals?

    <p>Contingency management</p> Signup and view all the answers

    Which medication among the following is potentially used as both an anticonvulsant and analgesic?

    <p>Gabapentin</p> Signup and view all the answers

    Which cognitive effect is associated with CB1 receptors in the hippocampus?

    <p>Memory impairment</p> Signup and view all the answers

    What are common withdrawal symptoms experienced after discontinuation of use?

    <p>Irritability and disrupted sleep</p> Signup and view all the answers

    Which psychiatric effect occurs at very high doses of cannabis?

    <p>Mild paranoia and acute depressive reactions</p> Signup and view all the answers

    How does tolerance develop differently in experienced cannabis users compared to novice users?

    <p>Experienced users are more sensitive to psychoactive effects.</p> Signup and view all the answers

    Which co-occurring disorder has a higher incidence among cannabis users?

    <p>Bipolar disorder</p> Signup and view all the answers

    What is the duration of cognitive effects after discontinuation of heavy cannabis use?

    <p>1 month</p> Signup and view all the answers

    What is the likelihood of developing dependence on cannabis based on general statistics?

    <p>1 out of 10 users</p> Signup and view all the answers

    Which symptom is less commonly associated with cannabis withdrawal?

    <p>Panic attacks</p> Signup and view all the answers

    What are the potential effects on infants exposed to cannabis during pregnancy?

    <p>Transient withdrawal signs and neurobehavioral deficits</p> Signup and view all the answers

    How does cannabis provide analgesic effects?

    <p>Modulates presynaptic CB receptors to reduce transmitter release.</p> Signup and view all the answers

    Which cannabinoid is commonly used to treat nausea following chemotherapy?

    <p>Nabilone (Cesamet)</p> Signup and view all the answers

    What psychoactive effects are associated with cannabis use?

    <p>Mild euphoria and enhanced creativity</p> Signup and view all the answers

    Which of the following is true about THC and neuroprotection?

    <p>THC reduces reactive oxygen intermediates.</p> Signup and view all the answers

    What effect does cannabis have on psychomotor function?

    <p>Persisting impairment affecting driving and attention</p> Signup and view all the answers

    How does cannabis influence appetite?

    <p>Stimulates appetite primarily for sweet and palatable foods</p> Signup and view all the answers

    What is a common misconception about the hallucinations caused by cannabis?

    <p>Illusions and hallucinations occur infrequently.</p> Signup and view all the answers

    What is the typical time frame for THC to reach its peak effects after administration?

    <p>Within 2 hours</p> Signup and view all the answers

    What is the primary mechanism through which THC is metabolized in the body?

    <p>Hepatic cytochrome P450 enzymes</p> Signup and view all the answers

    Which of the following statements is true regarding THC tolerance?

    <p>Reverse tolerance may occur with low THC levels.</p> Signup and view all the answers

    What physiological effect may occur from THC use concerning blood pressure?

    <p>Effects depend on user posture</p> Signup and view all the answers

    What is one potential long-term effect of THC storage in body fat?

    <p>Detectable THC levels in the blood for weeks</p> Signup and view all the answers

    Which metabolite is the inactive form of THC that is excreted in urine?

    <p>Carboxy-THC</p> Signup and view all the answers

    How does THC impact the immune system?

    <p>May impact immune function through CB2 receptors</p> Signup and view all the answers

    How long can a chronic smoker show positive results for THC in urine?

    <p>30 days or more</p> Signup and view all the answers

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