Pathology: Neoplastic diseases of bones and joints

Which bone tumor is most common in dogs?

Primary bone tumors are:

In dogs, most bone tumors are benign

Secondary tumors (metastases) of bones in animals are seldom diagnosed

How should canine osteosarcomas be regarded until proven otherwise?

Which anatomic locations are most commonly affected by osteosarcoma in dogs?

Osteosarcomas in dogs most commonly arise in:

What is the most common signalment for canine osteosarcoma?

Match the radiographic appearance of the different osteosarcomas

Which organ is the most common site for early metastasis of osteosarcoma?

Which of the following is true regarding osteosarcoma progression?

Microscopic metastases in the lungs could be missed in pulmonary radiographs

A characteristic radiographic finding in osteosarcoma involving elevation of the periosteum is called:

Why is Codman's triangle not a good site for biopsy sampling in suspected osteosarcoma?

What is the preferred location for biopsy in suspected osteosarcoma?

In a dog with osteosarcoma, you do NOT sample the periosteum

What are the two osteosarcoma subtypes?

Which osteosarcoma subtype contains irregular, broken capillaries within the tumor mass?

How can osteosarcoma subtypes be definitively identified?

Complete the sentence in the picture

Which of the following statements is true about osteosarcomas?

What is the second most common bone tumor in dogs?

Chondrosarcoma most commonly affects which bones?

Chondrosarcomas appear ______ grossly.

Chondrosarcomas are most common in small and giant breeds

Which of the following statements about Multilobular Tumor of Bone is TRUE?

Multilobuar tumor of bone has a classic appearance on histology

Which bone tumor is most commonly found in cats, especially at previous vaccination sites?

Skeletal fibrosarcomas originate from ____________, but may arise in metaphyses of long bones and resemble osteosarcomas

Skeletal fibrosarcoma in dogs is most commonly found:

______________ are known to cross the joint space

This lesion depicted above is caused by ____________

Plasma cell myeloma is best characterized by:

Which tumor is associated with increased serum globulin and a monoclonal gammopathy peak?

10% of plasma cell myeloma aka multiple myeloma cause hypercalcemia

Which of the following is a hallmark feature of humoral hypercalcemia of malignancy?

What is the underlying cause of humoral hypercalcemia of malignancy (pseudohyperparathyroidism)?

Which of the following tumors is not typically associated with humoral hypercalcemia of malignancy?

What is the primary mechanism by which neoplastic cells induce hypercalcemia of malignancy?

Which of the following best describes the effect of PTHrp on bone, kidney, and the gastrointestinal (GI) tract?

In a case of hypercalcemia of malignancy induced by PTHrp, what would you expect to observe regarding PTH levels?

Which of the following humoral factors directly contributes to increased calcium levels in humoral hypercalcemia of malignancy?

What is a KEY difference between the action of PTH and PTHrp in causing hypercalcemia?

Which tumor often invades bone by direct extension rather than true metastasis?

What is a key feature of osteomas?

Where are osteomas often found?

Ossifying fibromas are most commonly found in:

Which of the following benign tumors invades adjacent bone?

What is true of osteochondromas?

Which of the following benign tumors may cause spinal cord compression?

Match the joint neoplasms to its description/characteristics

Which neoplasm can spread to joints hematogenously?