Cancer Systemic Therapy and Treatment Assessment

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What is the primary mechanism of action for alkylating agents in chemotherapy?

Promotion of microtubule assembly and stability

Inhibition of DNA topoisomerases

Interference with microtubule assembly

Alkylation of RNA and proteins (correct)

Which class of drugs in chemotherapy is known for its mechanism of intercalation between DNA base pairs?

Plant alkaloids

Antimetabolites

Topoisomerase inhibitors

Antibiotics (correct)

What is the primary mechanism of action for topoisomerase I inhibitors in chemotherapy?

Alkylation and cross-linking of DNA

Promotion of microtubule assembly and stability

Interference with microtubule assembly

Inhibition of DNA topoisomerases (correct)

Which phase of the cell cycle do taxanes primarily affect?

M phase Signup and view all the answers

Which type of cancer shows a high level of chemosensitivity to chemotherapy?

Hodgkin’s disease Signup and view all the answers

Which neoplasm is among the main therapeutic modalities for chemotherapy?

Choriocarcinoma Signup and view all the answers

What is the primary mechanism of action for plant alkaloids, specifically Vinca alkaloids, in chemotherapy?

Blockage of microtubule polymerization Signup and view all the answers

In which phase of the cell cycle do antimetabolites primarily interfere?

S phase Signup and view all the answers

Which type of cancer is among the low level of chemosensitivity to chemotherapy?

Pancreatic cancer Signup and view all the answers

In which neoplasm can primary chemotherapy allow for less mutilating surgery?

Anal carcinoma Signup and view all the answers

Which class of drugs in chemotherapy is known for its mechanism of action involving DNA intercalation, inhibition of DNA topoisomerases, and free radical formation?

Antibiotics Signup and view all the answers

Which neoplasm is among the main therapeutic modalities for chemotherapy?

Hodgkin’s lymphoma Signup and view all the answers

What is the primary mechanism of action for anthracyclines in chemotherapy?

Intercalation between DNA base pairs and free radical formation Signup and view all the answers

In which phase of the cell cycle do antimetabolites primarily interfere?

S phase Signup and view all the answers

What is the primary mechanism of action for alkylating agents in chemotherapy?

Chemical interaction with DNA by forming covalent bonds with nucleic acid Signup and view all the answers

Which type of cancer shows a high level of chemosensitivity to chemotherapy?

Non-Hodkin’s lymphoma Signup and view all the answers

What is the primary mechanism of action for plant alkaloids, specifically Taxanes, in chemotherapy?

Promotion of microtubule assembly and stability Signup and view all the answers

Which class of drugs in chemotherapy is known for its mechanism of action involving interference with the action of topoisomerase enzymes?

Antimetabolites Signup and view all the answers

In which neoplasm can primary chemotherapy allow for less mutilating surgery?

Breast cancer Signup and view all the answers

What is the primary mechanism of action for nitrogen mustards in chemotherapy?

$cross-linking$ of DNA Signup and view all the answers

Which type of cancer shows a low level of chemosensitivity to chemotherapy?

$NSCLC$ (Non-Small Cell Lung Cancer) Signup and view all the answers

What is the primary mechanism of action for topoisomerase I inhibitors in chemotherapy?

Interference with topoisomerase enzymes that control changes in DNA Signup and view all the answers

Cancer Systemic Therapy and Treatment Assessment

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Questions and Answers

What is the primary mechanism of action for alkylating agents in chemotherapy?

Which class of drugs in chemotherapy is known for its mechanism of intercalation between DNA base pairs?

What is the primary mechanism of action for topoisomerase I inhibitors in chemotherapy?

Which phase of the cell cycle do taxanes primarily affect?

Which type of cancer shows a high level of chemosensitivity to chemotherapy?

Which neoplasm is among the main therapeutic modalities for chemotherapy?

What is the primary mechanism of action for plant alkaloids, specifically Vinca alkaloids, in chemotherapy?

In which phase of the cell cycle do antimetabolites primarily interfere?

Which type of cancer is among the low level of chemosensitivity to chemotherapy?

In which neoplasm can primary chemotherapy allow for less mutilating surgery?

Which class of drugs in chemotherapy is known for its mechanism of action involving DNA intercalation, inhibition of DNA topoisomerases, and free radical formation?

Which neoplasm is among the main therapeutic modalities for chemotherapy?

What is the primary mechanism of action for anthracyclines in chemotherapy?

In which phase of the cell cycle do antimetabolites primarily interfere?

What is the primary mechanism of action for alkylating agents in chemotherapy?

Which type of cancer shows a high level of chemosensitivity to chemotherapy?

What is the primary mechanism of action for plant alkaloids, specifically Taxanes, in chemotherapy?

Which class of drugs in chemotherapy is known for its mechanism of action involving interference with the action of topoisomerase enzymes?

In which neoplasm can primary chemotherapy allow for less mutilating surgery?

What is the primary mechanism of action for nitrogen mustards in chemotherapy?

Which type of cancer shows a low level of chemosensitivity to chemotherapy?

What is the primary mechanism of action for topoisomerase I inhibitors in chemotherapy?

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