Can You Differentiate False Positive and True Positive Results in Coronary Arter...
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Questions and Answers

What is the purpose of distinguishing between a false positive and a true positive?

  • To increase the number of referrals for invasive coronary angiography
  • To diagnose obstructive coronary artery disease
  • To avoid unnecessary referrals for invasive coronary angiography (correct)
  • To decrease the accuracy of treadmill exercise ECG testing
  • What is a false positive TMT result?

  • An ischemic response and obstructive coronary artery disease
  • No ischemic response and obstructive coronary artery disease
  • An ischemic response and no obstructive coronary artery disease (correct)
  • No ischemic response and no obstructive coronary artery disease
  • What was used to evaluate the performance of the model based on predictive factors?

  • The type of coronary artery disease risk factors assessed
  • The number of patients in the cohort
  • The number of invasive coronary angiography referrals
  • The area under the ROC curve (correct)
  • Study Notes

    • False positive results are common in treadmill exercise ECG testing for obstructive coronary artery disease screening.
    • It is important to distinguish between a false positive and a true positive to avoid unnecessary referrals for invasive coronary angiography.
    • The study analyzed a cohort of patients referred for ICA for stable coronary artery disease diagnosis.
    • Traditional and nontraditional coronary artery disease risk factors were assessed.
    • Modified Framingham risk score, symptoms, pre-test probability of OCAD, left ventricular ejection fraction and ICA results were also evaluated.
    • A FP TMT result was defined as an ischemic response and no OCAD.
    • The predictors of a FP result were determined through statistical tests and multivariate analysis.
    • The discriminatory power of a model based on predictive factors was assessed.
    • The study was conducted in a single tertiary-care center from 2006-2011.
    • The area under the ROC curve was used to evaluate the model's performance.

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    Description

    Test your knowledge on false positive results in treadmill exercise ECG testing for obstructive coronary artery disease screening. Learn about the importance of distinguishing between true and false positives to avoid unnecessary referrals for invasive coronary angiography. Explore the predictors of a false positive result and the evaluation of a model based on predictive factors. This quiz covers traditional and nontraditional coronary artery disease risk factors, modified Framingham risk score, symptoms, pre-test probability of OCAD, left ventricular ejection fraction, and ICA results

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