Calorimetry: Direct vs Indirect

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Questions and Answers

What is the definition of a calorie (cal)?

  • Amount of heat required to raise the temperature of 1 g of water by 1°C (correct)
  • Total energy available from food consumption
  • Amount of energy expended during 1 minute of exercise
  • Amount of heat required to raise the temperature of 1 kg of water by 1°C

Which statement correctly describes the relationship between $VO_{2max}$ and cardiovascular disease risk?

  • $VO_{2max}$ is inversely related to cardiovascular disease risk. (correct)
  • $VO_{2max}$ is not related to cardiovascular disease risk.
  • $VO_{2max}$ is only related to cardiovascular disease risk in elderly individuals
  • $VO_{2max}$ is directly related to cardiovascular disease risk.

What is the primary purpose of calorimetry?

  • To determine the volume and concentration of inspired gases
  • To measure the electrical activity of the heart
  • To determine the amount of energy used during exercise by measuring expired gases (correct)
  • To measure body temperature

Which type of calorimetry involves measuring heat production directly by monitoring temperature changes in a controlled environment?

<p>Direct calorimetry (B)</p> Signup and view all the answers

Which of the following best describes open circuit indirect calorimetry?

<p>Analyzing expired gases to estimate energy expenditure (C)</p> Signup and view all the answers

What is the purpose of converting gas volumes to STPD (Standard Temperature and Pressure Dry)?

<p>To allow comparison of gas volumes under different conditions (B)</p> Signup and view all the answers

According to the information provided, what equation is used in step 3 to calculate $V_I$ (inspired volume)?

<p>$V_I (STPD) = V_E (STPD) \times (F_EN_2 / F_IN_2)$ (D)</p> Signup and view all the answers

What does the acronym BTPS stand for in the context of respiratory physiology?

<p>Body Temperature and Pressure Saturated (C)</p> Signup and view all the answers

What happens to ventilation ($V_E$) as exercise intensity increases?

<p>Ventilation increases progressively. (B)</p> Signup and view all the answers

During submaximal exercise, how does $F_EO_2$ (fraction of oxygen in expired air) typically change?

<p>$F_EO_2$ decreases progressively (C)</p> Signup and view all the answers

How does $F_ECO_2$ (fraction of carbon dioxide in expired air) change during moderate exercise?

<p>$F_ECO_2$ progressively increases (B)</p> Signup and view all the answers

What typically happens to $V_O2$ (oxygen consumption) during exercise as power output increases?

<p>$V_O2$ increases linearly (B)</p> Signup and view all the answers

According to the provided information, what happens to tidal volume ($V_T$) during submaximal exercise?

<p>Tidal volume increases progressively (C)</p> Signup and view all the answers

During maximal exercise, what tends to occur with respiratory rate?

<p>Respiratory rate plateaus at final stages (A)</p> Signup and view all the answers

What happens to minute ventilation ($V_E$) at the final stages of maximal exercise?

<p>$V_E$ plateaus (A)</p> Signup and view all the answers

What happens to $F_EO_2$ (fraction of expired oxygen) during maximal exercise?

<p>$F_EO_2$ increases at final stages (C)</p> Signup and view all the answers

What generally occurs with $F_ECO_2$ (fraction of expired carbon dioxide) during maximal exercise?

<p>$F_ECO_2$ decreases at final stages (B)</p> Signup and view all the answers

What is a typical response of $V_O2$ (oxygen consumption) during maximal exercise?

<p>$V_O2$ plateaus at final stages (A)</p> Signup and view all the answers

According to the information, what happens to the respiratory exchange ratio (RER) during submaximal exercise?

<p>RER increases (A)</p> Signup and view all the answers

What is the typical response of the respiratory exchange ratio (RER) during maximal exercise?

<p>RER decreases or plateaus (A)</p> Signup and view all the answers

Flashcards

Caloric Cost of Exercise

The caloric (energy) cost estimated from oxygen used during exercise (VO2).

Calorie (cal)

Amount of heat/energy needed to raise 1 g of water by 1 °C.

Kilocalorie (kcal)

Amount of heat/energy needed to raise 1 kg of water by 1 °C.

Calorimetry

Determining energy used during exercise by measuring volume and concentration of expired gases.

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Maximal Oxygen Uptake (VO2max)

Gold standard measure of cardiorespiratory fitness, inversely related to cardiovascular disease risk.

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Direct Calorimetry

Measures heat production directly using insulated chamber.

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Indirect Calorimetry

Estimates heat production via oxygen consumption. Can be open or closed circuit

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Open Circuit Indirect Calorimetry

Measuring expired gases during exercise.

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BTPS

Body Temperature and Pressure Saturated; air in the body.

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ATPS

Atmospheric Temperature and Pressure Saturated; expired air.

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STPD

Standard Temperature and Pressure Dry; standardized air.

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Conversion of Gases to STPD

Applying a formula to compare results from tests done on different days or locations.

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Ventilation During Exercise

Ventilation increases progressively.

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FEO2 During Exercise

Decreases during moderate exercise, then increases during strenuous exercise; hyperventilation.

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FECO2 During Exercise

Increases during moderate exercise then decreases during strenuous exercise.

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Tidal Volume During Exercise

tidal volumne increases progressively

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Respiratory Rate During Exercise

Respiratory Rate increases progressively

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Expired Oxygen During Exercise

Expired oxygen decreases progressively

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Expired Carbon Dioxide During Exercise

Expired Carbon Dioxide increases Progressively

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VO2 During Exercise

VO2 (L.min-1) increases Progressively

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Study Notes

  • The caloric (energy) cost of exercise can be estimated from the amount of oxygen used during exercise (VO2).
  • Calorie (cal) refers to the amount of heat (energy) required to raise the temperature of 1 g of water 1 °C.
  • Kilocalorie (kCal) refers to the amount of heat (energy) required to raise the temperature of 1 kg of water 1 °C.
  • One can calculate the volume and concentration of expired gases to determine the amount of energy used during exercise.
  • Maximal Oxygen Uptake (VO2max) is the gold standard measure of cardiorespiratory fitness.
  • VO2max is inversely related cardiovascular disease risk.

Calorimetry types

  • Direct
  • Indirect
    • Open circuit
    • Closed Circuit

Direct Calorimetry

  • Direct Calorimetry involves measuring the amount of heat produced by the body.

Indirect Calorimetry

  • Indirect Calorimetry involves measuring the amount of oxygen consumed.
  • Open circuit
  • Can be manual or automated
  • Open circuit is a usual testing method employed in an exercise physiology lab.

Graded Exercise Testing

  • Continuous GXT
  • 3 min stages
  • Workloads: 40 W, 80 W, 120 W
  • Collect HR & expired gas throughout each stage
  • Assign a role to each person

BTPS, ATPS, STPD?

  • BTPS = Body Temperature and Pressure Saturated (Air in the Body)
  • ATPS = Atmospheric Temperature and Pressure Saturated (Expired Air)
  • STPD = Standard Temperature and Pressure Dry (Standardised Air)
  • Conversion of gases to STPD allows one to compare results from tests performed on separate days or locations.
  • Use STPD when calculate gas volumes.

STPD

  • STPD = Standard Temperature and Pressure Dry
  • Temperature = 273.15 K (0°C)
  • Pressure = 101.3 kpa (760 mmHg)

Calculating Expired & Inspired Gas Variables

  • Measured:
    • VE (L.min-1) (ATPS)
    • FEO2
    • FECO2
  • Needed to calculate:
    • VE (L.min-1) (STPD)
    • V₁ (L.min-1)
    • F₁O2
    • F₁CO2
    • VO2 (L.min-1)
    • VCO2 (L.min-1)
    • RER

Calculating VO2 & VCO2

  • Step 1- Convert ATPS to STPD
  • Step 2 - Calculate VEO2 & VECO2:
    • VEO2 = VE (STPD) X FEO2
    • VECO2 = VE (STPD) X FECO2
  • Step 3- Calculate V₁:
    • V₁ (STPD) = VE (STPD) X (FEN2/F1N2)
    • V₁ (STPD) = VE (STPD) x (1-FEO2-FECO₂)/(1-F₁O2-F,CO2)
  • Step 4 - Calculate V₁O₂ & V₁CO2:
    • V₁O2 = V₁ (STPD) x F₁O2 (0.2093)
    • V₁CO₂ = V₁ (STPD) x F₁O2 (0.0035)
  • Step 5 - Calculate VO2 & VCO2:
    • VO2 = V1O2 - VEO2
    • VCO2 = VECO2-V,CO2

Response to Exercise – VE

  • Ventilation increases progressively with exercise intensity.

Response to Exercise – FEO2

  • Decreases during moderate exercise
  • Increases during strenuous exercise (hyperventilation)

Response to Exercise – FECO₂

  • Increases progressively during moderate exercise
  • Decreases during strenuous exercise (hyperventilation)

Respiratory Changes During Exercise

Parameter | Submax Exercise | Max Exercise

  • ------ | -------- | -------- Tidal Volume | ↑ progressively | Plateaus Respiratory Rate | ↑ progressively | Plateaus at final stages VE (L.min-1) | ↑ progressively | Plateaus at final stages FEO2 | ↓ progressively | ↑ at final stages FECO2 | ↑ progressively | ↓ at final stages VO2 (L.min-1) | ↑ progressively | ↓ or plateaus RER | ↑ | ↑ or plateaus

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