Podcast
Questions and Answers
What is the role of antiresorptive agents in the management of osteoporosis?
What is the role of antiresorptive agents in the management of osteoporosis?
- Transport calcium ions across intestinal epithelial cells
- Stimulate osteoblastic bone formation
- Depress osteoclasts and diminish bone resorption (correct)
- Increase PTH expression in parathyroid chief cells
Which medication is an example of a calcimimetic agent used to address hypercalcemia?
Which medication is an example of a calcimimetic agent used to address hypercalcemia?
- Teriparatide
- Cinacalcet (correct)
- Denosumab
- Romosozumab
What is the primary target of Calcitriol in the body?
What is the primary target of Calcitriol in the body?
- Intestinal epithelial cells (correct)
- Parathyroid chief cells
- Osteoblasts
- Osteoclasts
Intravenous calcium gluconate or calcium chloride is used for the treatment of severe or chronic:
Intravenous calcium gluconate or calcium chloride is used for the treatment of severe or chronic:
What is the main action of anabolic agents in the context of osteoporosis treatment?
What is the main action of anabolic agents in the context of osteoporosis treatment?
Which medication is an example of an antibody against sclerostin used for osteoporosis treatment?
Which medication is an example of an antibody against sclerostin used for osteoporosis treatment?
What is the main role of R2 site in Bisphosphonates?
What is the main role of R2 site in Bisphosphonates?
How does Denosumab work in treating hypercalcemia?
How does Denosumab work in treating hypercalcemia?
What is the mechanism of action of Cinacalcet in treating hyperparathyroidism?
What is the mechanism of action of Cinacalcet in treating hyperparathyroidism?
Which molecule is involved in the activation, differentiation, and apoptosis of osteoclasts?
Which molecule is involved in the activation, differentiation, and apoptosis of osteoclasts?
Why are both phosphonate groups essential for Bisphosphonates' action?
Why are both phosphonate groups essential for Bisphosphonates' action?
Which drug is a monoclonal antibody that functions as a RANK ligand inhibitor?
Which drug is a monoclonal antibody that functions as a RANK ligand inhibitor?
What is the mechanism of action of Romosozumab (Evenity)?
What is the mechanism of action of Romosozumab (Evenity)?
What effect do estrogens have on osteoclast activity?
What effect do estrogens have on osteoclast activity?
How do Selective Estrogen Receptor Modulators (SERMs) differ from estrogens?
How do Selective Estrogen Receptor Modulators (SERMs) differ from estrogens?
What is the primary function of Raloxifene as a SERM?
What is the primary function of Raloxifene as a SERM?
How do Romosozumab, Teriparatide, and Abaloparatide differ in their effects on bone?
How do Romosozumab, Teriparatide, and Abaloparatide differ in their effects on bone?
What is the role of sclerostin in bone metabolism?
What is the role of sclerostin in bone metabolism?
Which of the following is a parathyroid hormone-related protein analog?
Which of the following is a parathyroid hormone-related protein analog?
Which of the following is a sclerostin inhibitor?
Which of the following is a sclerostin inhibitor?
Which of the following is NOT a function of bisphosphonates?
Which of the following is NOT a function of bisphosphonates?
Which of the following is NOT an anabolic agent to stimulate osteoblastic bone formation?
Which of the following is NOT an anabolic agent to stimulate osteoblastic bone formation?
Which of the following statements is NOT correct regarding bisphosphonates?
Which of the following statements is NOT correct regarding bisphosphonates?
What are the two thyroid hormones responsible for calcium homeostasis?
What are the two thyroid hormones responsible for calcium homeostasis?
What does Parathyroid hormone signaling increase in osteoblasts and osteocytes?
What does Parathyroid hormone signaling increase in osteoblasts and osteocytes?
What does Osteoprotegerin (OPG) do to protect the skeleton from excessive bone resorption?
What does Osteoprotegerin (OPG) do to protect the skeleton from excessive bone resorption?
What is the physiological process in which old or damaged bone is removed by osteoclasts (bone-resorbing cells), then replaced by new bone formed by osteoblasts (bone-forming cells)?
What is the physiological process in which old or damaged bone is removed by osteoclasts (bone-resorbing cells), then replaced by new bone formed by osteoblasts (bone-forming cells)?
Which of the following is NOT a disorder of calcium homeostasis?
Which of the following is NOT a disorder of calcium homeostasis?
What regulates osteoclast development and bone metabolism?
What regulates osteoclast development and bone metabolism?
