Calcium and Phosphorus
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Questions and Answers

Which of the following is the primary form in which calcium is stored in bone?

  • Calcium carbonate
  • Calcium hydroxide
  • Calcium phosphate (correct)
  • Calcium sulfate
  • What is the normal range for total plasma calcium concentration?

  • 8.8 - 10.3 mg/dL (correct)
  • 0.81 - 1.45 mmol/L
  • 2.2 - 2.6 mg/dL
  • 4.4 - 5.2 mmol/L
  • Which of the following is NOT a function of calcium in the body?

  • Enzymes activity
  • Apoptosis
  • Cholesterol synthesis (correct)
  • Blood coagulation
  • What percentage of total plasma calcium concentration is bound to protein?

    <p>45%</p> Signup and view all the answers

    What is the primary function of PTH (parathyroid hormone)?

    <p>Decrease calcium and phosphate release from bones</p> Signup and view all the answers

    Which organ is primarily responsible for the production of 1,25-dihydroxyvitamin D?

    <p>Kidney</p> Signup and view all the answers

    What is the role of the GI tract in calcium and phosphate homeostasis?

    <p>Absorption of calcium and phosphate from the diet</p> Signup and view all the answers

    What is the hormonal response to hypocalcemia?

    <p>Increase in PTH secretion</p> Signup and view all the answers

    Which hormone increases plasma [Ca2+] and decreases plasma [Pi]?

    <p>Parathyroid hormone (PTH)</p> Signup and view all the answers

    Which hormone directly acts on the parathyroid glands and indirectly regulates plasma [Ca2+] through a negative feedback mechanism?

    <p>Vitamin D</p> Signup and view all the answers

    Which hormone decreases plasma [Ca2+] and [Pi]?

    <p>Calcitonin</p> Signup and view all the answers

    Which hormone stimulates the synthesis of 1,25(OH)2D3 in the kidney?

    <p>Parathyroid hormone (PTH)</p> Signup and view all the answers

    Which hormone is classified as a steroid hormone and is the active form of Vitamin D?

    <p>Vitamin D</p> Signup and view all the answers

    Which of the following is NOT a source of vitamin D?

    <p>Sun exposure</p> Signup and view all the answers

    Which form of vitamin D is more effective: D2 or D3?

    <p>D3</p> Signup and view all the answers

    What is the desirable concentration of 25(OH) D3 in the body?

    <p>Between 50-75 ng/mL</p> Signup and view all the answers

    What is the main role of calcitriol in the body?

    <p>Regulating bone resorption and deposition</p> Signup and view all the answers

    What effect does calcitonin have on bone resorption?

    <p>It inhibits osteoclast activity</p> Signup and view all the answers

    Which of the following is the key factor that determines the threshold voltage to fire an action potential?

    <p>Voltage-gated Na channels activation</p> Signup and view all the answers

    Which of the following is the treatment for rickets?

    <p>Both calcium and phosphate supplementation and vitamin D supplementation</p> Signup and view all the answers

    What is the most common metabolic bone disease with significant morbidity and mortality?

    <p>Osteoporosis</p> Signup and view all the answers

    What is the expected effect of blocking the Ca-sensing receptor (CaSR) with an antiCaSR antibody?

    <p>Increased PTH synthesis</p> Signup and view all the answers

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