Ageing - Skin
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Ageing - Skin

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@HearteningEnglishHorn

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Questions and Answers

What are the structural changes to ageing skin?

Loss of rete ridges, thinner epidermis, smoother epidermal/dermis barrier, less adherence

Increased expression of matrix metalloproteases (MMP) does what?

  • Degrade Fibrillins/GAGs
  • Degrade Collagen/Elastin (correct)
  • Form Collagen/Elastin
  • Form Fibrillins/GAGs

    • What does this induce?

    Apoptosis

    What does UV light/smoking affect?

    <p>DNA stability, mutations, promotor cellular malignant transformations</p> Signup and view all the answers

    How does UV light/smoking affect DNA stability?

    <p>Accumulation of ROS, and p53 inability to remove them</p> Signup and view all the answers

    What is the inflammation of the skin caused by?

    <p>Interleukins, immunosuppression and MMP</p> Signup and view all the answers

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