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Ageing - Skin

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Questions and Answers

What are the structural changes to ageing skin?

Loss of rete ridges, thinner epidermis, smoother epidermal/dermis barrier, less adherence

Increased expression of matrix metalloproteases (MMP) does what?

Degrade Fibrillins/GAGs

Degrade Collagen/Elastin (correct)

Form Collagen/Elastin

Form Fibrillins/GAGs

What does this induce?

Apoptosis

What does UV light/smoking affect?

DNA stability, mutations, promotor cellular malignant transformations Signup and view all the answers

How does UV light/smoking affect DNA stability?

Accumulation of ROS, and p53 inability to remove them Signup and view all the answers

What is the inflammation of the skin caused by?

Interleukins, immunosuppression and MMP Signup and view all the answers

Ageing - Skin

Choose a study mode

Podcast

Questions and Answers

What are the structural changes to ageing skin?

Increased expression of matrix metalloproteases (MMP) does what?

What does this induce?

What does UV light/smoking affect?

How does UV light/smoking affect DNA stability?

What is the inflammation of the skin caused by?

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