BSC2010-U04: Control of Gene Expression Quiz

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Questions and Answers

What is the main way controlling gene expression is achieved?

  • By controlling transcription initiation (correct)
  • By controlling translation initiation
  • By controlling translation elongation
  • By controlling transcription elongation

How do regulatory proteins influence transcription?

  • By blocking or stimulating transcription based on their interaction with RNA polymerase (correct)
  • By inhibiting translation
  • By activating transcription factors
  • By directly editing the DNA sequence

In prokaryotic organisms, what are operons?

  • Regulatory regions that bind to RNA polymerase
  • Sequences of DNA where transcription initiation is controlled positively
  • Clusters of genes under the control of a single operator (correct)
  • Sequences of DNA encoding regulatory proteins

What is the role of operators in prokaryotic gene regulation?

<p>To regulate the activity of RNA polymerase (D)</p> Signup and view all the answers

Where does RNA polymerase bind in relation to the coding region of a gene in prokaryotes?

<p>Immediately upstream from the region that codes for a protein (A)</p> Signup and view all the answers

What does positive control achieve in prokaryotic gene regulation?

<p>Increases transcription when activators bind DNA (D)</p> Signup and view all the answers

What is the main role of acetylated histones in relation to DNA?

<p>Enhance DNA accessibility for transcription (A)</p> Signup and view all the answers

Which process is NOT a part of posttranscriptional regulation?

<p>Histone acetylation (B)</p> Signup and view all the answers

What occurs during alternative splicing?

<p>Splicing out of introns to form mature mRNA (C)</p> Signup and view all the answers

What is the main outcome of RNA editing?

<p>Create mature mRNA not accurately encoded by the genome (D)</p> Signup and view all the answers

Which process involves the inhibition of gene expression or translation by neutralizing targeted mRNA molecules?

<p>RNA interference (D)</p> Signup and view all the answers

What is a role of translation repressor proteins in posttranscriptional regulation?

<p>Interfere with translation process (C)</p> Signup and view all the answers

How does ATP-dependent remodeling factor contribute to eukaryotic chromosome structure?

<p>Promotes nucleosome sliding and remodeling (C)</p> Signup and view all the answers

What is the main function of miRNA and siRNA in RNA interference?

<p>Inhibiting gene expression (B)</p> Signup and view all the answers

Which RNA molecule is involved in the degradation of miRNA and siRNA?

<p>circRNA (A)</p> Signup and view all the answers

What is the primary mechanism through which proteins are degraded when marked with ubiquitin?

<p>Proteasome degradation (B)</p> Signup and view all the answers

Which type of RNA molecule is 22 nucleotides in length and involved in the repression of a gene post-transcription?

<p>miRNA (B)</p> Signup and view all the answers

Who were the Nobel prize recipients credited with the discovery of the CRISPR genome editing technique?

<p>Emmanuelle Charpentier and Jennifer Doudna (D)</p> Signup and view all the answers

What is required for transcription initiation in eukaryotic gene regulation?

<p>General transcription factors (C)</p> Signup and view all the answers

Which type of factors increase transcription in certain cells or in response to signals in eukaryotic gene regulation?

<p>Specific transcription factors (A)</p> Signup and view all the answers

What is the function of coactivators and mediators in the transcription complex?

<p>Bind to transcription factors (C)</p> Signup and view all the answers

Where do general transcription factors bind in the gene during eukaryotic regulation?

<p>Promoter region (D)</p> Signup and view all the answers

What is the association of methylated histone proteins with inactive regions of chromatin?

<p>They prevent activators from binding to DNA (D)</p> Signup and view all the answers

Which DNA sequences cause activation of transcription when specific transcription factors bind to them?

<p>Enhancers (B)</p> Signup and view all the answers

What is the function of the promoter in prokaryotic gene regulation?

<p>Positioning the polymerase correctly (C)</p> Signup and view all the answers

Which type of regulation is exhibited by the trp operon?

<p>Repressible regulation with tryptophan (A)</p> Signup and view all the answers

What is the role of cAMP in prokaryotic gene regulation?

<p>Activates CAP for better binding of RNA polymerase (C)</p> Signup and view all the answers

In the lac operon, what happens when lactose is present?

<p>An inducer molecule binds to the repressor (D)</p> Signup and view all the answers

How does glucose affect the lac operon?

<p>Enhances RNA polymerase binding to the promoter (A)</p> Signup and view all the answers

What is the consequence of low levels of tryptophan in the trp operon?

<p>Repressor binds to operator (C)</p> Signup and view all the answers

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