Breast Cancer Genetics and Management Quiz
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Questions and Answers

What should be done first for a local recurrence of breast cancer?

  • Biopsy the recurrence (correct)
  • Whole-body MRI
  • Systemic chemotherapy
  • Surgical excision

    • What genetic mutation is associated with a 50-85% lifetime risk of developing breast cancer?

  • BRCA1 (correct)
  • Peutz-Jeghers syndrome
  • Cowden syndrome
  • BRCA2

    • What is the primary characteristic of hereditary breast cancer (HBC)?

  • Associated with environment factors
  • Affects only one family member
  • Linked to identifiable genetic mutations (correct)
  • Present at older age

    • In pregnancy, which imaging technique is recommended when bone or brain metastasis is suspected?

    <p>MRI without gadolinium contrast</p> Signup and view all the answers

    Which of the following breast cancer types is typically associated with BRCA1 mutation?

    <p>Triple-negative breast cancer</p> Signup and view all the answers

    What is one of the recommended options for women with a BRCA mutation to reduce their breast cancer risk?

    <p>Bilateral risk-reducing mastectomy</p> Signup and view all the answers

    Familial breast cancer (FBC) differs from hereditary breast cancer (HBC) primarily because FBC:

    <p>Is not attributable to any known genetic mutation</p> Signup and view all the answers

    What percentage of all breast cancers is accounted for by hereditary breast cancer (HBC)?

    <p>5-10%</p> Signup and view all the answers

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