Brainstem Anatomy: Medulla, Pons, Cerebellum
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Questions and Answers

Which of the following structures is located in the pons?

  • Inferior olivary nucleus
  • Hypoglossal nucleus
  • Dorsal motor nucleus of the vagus nerve
  • Facial motor nucleus (correct)

Which artery does NOT directly contribute to the blood supply of the brainstem?

  • Vertebral artery
  • Anterior cerebral artery (ACA) (correct)
  • Superior cerebellar artery (SCA)
  • Basilar artery

Which of the following cranial nerve nuclei is found in the medulla?

  • Hypoglossal nucleus (correct)
  • Trochlear nucleus
  • Abducens nucleus
  • Trigeminal motor nucleus

A lesion affecting the superior cerebellar artery (SCA) would most likely impact which of the following structures?

<p>Cerebellum and pons (C)</p> Signup and view all the answers

The decussation of the pyramids is a key anatomical feature of which brainstem region?

<p>Medulla (B)</p> Signup and view all the answers

Which of the following is a key function associated with the anterolateral system (ALS)?

<p>Pain and temperature sensation (A)</p> Signup and view all the answers

Which structure serves as the primary connection between the brainstem and the cerebellum?

<p>Cerebellar peduncles (B)</p> Signup and view all the answers

Damage to the medial longitudinal fasciculus (MLF) in the brainstem would most likely result in:

<p>Internuclear ophthalmoplegia (INO) (A)</p> Signup and view all the answers

Which of the following descending tracts originates in the red nucleus and plays a role in motor control?

<p>Rubrospinal tract (C)</p> Signup and view all the answers

Which of the following is a typical feature of Wallenberg syndrome (lateral medullary syndrome)?

<p>Contralateral loss of pain and temperature sensation from the body (D)</p> Signup and view all the answers

Which of the following is NOT part of the brainstem?

<p>Cerebellum (B)</p> Signup and view all the answers

The anterior spinal artery primarily supplies which portion of the spinal cord?

<p>Lateral corticospinal tract (C)</p> Signup and view all the answers

What deficits would be expected from damage centered around the inferior cerebellar peduncle?

<p>Problems in coordinating movements (C)</p> Signup and view all the answers

In the context of brainstem vascular syndromes, what is the most likely consequence of an infarction affecting the paramedian branches of the basilar artery?

<p>Medial medullary syndrome (A)</p> Signup and view all the answers

If a patient presents with a lesion in the brainstem affecting the abducens nerve (CN VI), what specific function is most likely to be impaired?

<p>Lateral eye movement (D)</p> Signup and view all the answers

A patient exhibits deficits in tactile discrimination and proprioception on the right side of their body. Where is the lesion most likely located?

<p>Left dorsal column-medial lemniscus pathway (A)</p> Signup and view all the answers

Following a traumatic injury, a patient has impaired motor function and loss of pain and temperature sensation on the left side of their body. Where would you expect the lesion to be located?

<p>Right medulla, affecting corticospinal tract and spinothalamic tract. (A)</p> Signup and view all the answers

A patient exhibits vertigo, nausea, and nystagmus after a stroke. Which of the following structures is most likely affected?

<p>Vestibular nuclei (B)</p> Signup and view all the answers

What is the expected outcome of a lesion to the middle cerebellar peduncle?

<p>Ipsilateral ataxia (D)</p> Signup and view all the answers

Which of the following best describes the vascular supply to the medulla?

<p>Supplied by branches of the basilar and vertebral arteries. (C)</p> Signup and view all the answers

A patient presents with paralysis on one side of the body and loss of proprioception on the other. Where is the most probable location of the lesion?

<p>Brainstem (D)</p> Signup and view all the answers

What is the primary function that would be affected if a lesion occurred in the tectum of the midbrain?

<p>Processing of auditory reflexes (C)</p> Signup and view all the answers

When a patient has damage to the lateral medulla, what deficits could be expected?

<p>All of the above (D)</p> Signup and view all the answers

Which part of the brainstem plays a critical role in relaying motor and sensory information between the cerebral cortex and the cerebellum?

<p>Pons (C)</p> Signup and view all the answers

What deficits does a patient experience when they experience damage to the hypoglossal nerve?

<p>Tongue weakness (C)</p> Signup and view all the answers

Flashcards

Medulla Oblongata

The lower part of the brainstem, contains vital control centers (e.g., breathing, heart rate).

Pons

The middle part of the brainstem, relays signals and contains nuclei for cranial nerves.

Cerebellum

Important for motor control, coordination, and balance.

Fiber Tract

Bundle of axons carrying specific information.

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Basilar Artery

Supplies blood to the posterior brain, formed by vertebral arteries.

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PICA (Posterior Inferior Cerebellar Artery)

Supplies the lateral medulla; infarction leads to Wallenberg syndrome.

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Abducens Nerve (VI)

Cranial nerve that controls eye movement, exits the brainstem at pons.

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Brainstem Anatomy

Inferior view structures: Crus cerebri, Pons, pre- and post-olivary sulci, olivary eminence, pyramids and restiform body.

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CN Exit points of Brainstem

Brainstem exit points, pons: IV (dorsal exit), V pons/medulla: VI, VII, VIII medulla: post olivary sulci IX, X pre- olivary sulci XII

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Brainstem Anatomy

Superior & inferior colliculi, cerebral peduncles, restiform body, gracile and cuneate tubercles.

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Primary Fissure

divides the cerebellum's anterior and posterior lobes.

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Corticospinal Tract (CST)

Descending tract controlling voluntary movement; originates in cerebral cortex.

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Pyramidal Decussation

Located in medulla, where CST fibers cross over.

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DCML (Dorsal Column Medial Lemniscus)

Ascending pathway for tactile and proprioceptive information.

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ALS (Anterolateral System)

Ascending pathway for pain, temperature, and crude touch.

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VPL Nucleus (Ventral Posterolateral)

Receives ALS signals on thalamus, relays to somatosensory cortex.

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Dorsal Horn

Dorsal region of spinal cord; receives sensory input.

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Gracile and Cuneate Nuclei

Relay nuclei for sensory pathways in the medulla.

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Wallenberg Syndrome

Lateral medulla infarction; vertigo, ataxia, sensory deficits.

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Anterolateral System Damage

Causes sensory deficits and impaired pain/temperature sensation.

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Mid-Pons Sectional Anatomy

Superior medullary velum, Superior Cerebellar peduncle, MLF, and Reticular formation

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Cerebellar Peduncles

Connect brainstem and cerebellum

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Vertebral Artery

Damage causes wallenberg syndrome

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Vertebral artery syndrome

Anteriolaral system, spinal trigeminal...

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Brainstem Strokes

Wallenberg (lateral medullary syndrome) and Dejerine (medial medullary) .

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Study Notes

  • Focus is on the medulla, pons, and cerebellum.
  • Key aspects include external anatomy, fiber tracts, sections, major blood supply, and vascular syndromes of the brainstem.
  • Also covers lateral and medial medullary and pontine syndromes.

Brainstem Anatomy - Inferior View

  • Key features include the crus cerebri (cerebral peduncles), pons (brachium pontis), pre- and post-olivary sulci, olivary eminence, pyramids, and restiform body.
  • 1 = posterior median sulcus.
  • 2 = posterior intermediate sulcus.
  • 3 = posterolateral sulcus.
  • 4 = anterior median sulcus.
  • 5 = anterolateral sulcus.

Brainstem Exit Points

  • Pons: IV (dorsal exit) and V.
  • Pons/medulla: VI, VII, VIII.
  • Cerebello-pontine angle: Interface of the pons, medulla, and cerebellum (VII, VIII).
  • Medulla: post olivary sulci IX, X, pre-olivary sulci XII.

Brainstem Anatomy - Superior View

  • Key features include the vermis, anterior lobe, primary fissure, folia, cerebellar hemisphere (intermediate and lateral parts), superior and inferior colliculi, crus cerebri (cerebral peduncles), restiform body, gracile, and cuneate tubercles.
  • Also includes striae medullares, vagal trigone, hypoglossal trigone, and facial colliculus.

Cerebellum - External Anatomy

  • Key components include the anterior lobe, posterior lobe, vermis, intermediate hemisphere, lateral hemisphere, and tonsils.
  • Also includes the primary fissure, horizontal fissure, postero-lateral fissure, flocculo-nodular lobe, nodulus, and flocculus.

Descending Pathways - Major (Corticospinal Tract)

  • Cortical upper motor neurons (UMNs).
  • Internal capsule and Crus Cerebri (cerebral peduncles).
  • Pontine and medullary CST, Pyramids.
  • Decussation becomes LCS (in lateral funiculus).
  • No Decussation becomes ACS (in anterior funiculus).
  • Ventral horn lower motor neuron (LMN).

Rubrospinal Tract

  • Red nucleus.
  • Ventral tegmental decussation occurs in the midbrain.
  • Exists in the lateral funiculus
  • Proximal limb flexor LMN.

Ascending Pathways - Major (DCML)

  • DCML handles tactile and proprioceptive information via the dorsal column medial lemniscus.
  • Two dorsal columns (fasciculi): Gracile (lower extremities), Cuneate (upper extremities).
  • Two medullary nuclei: gracile and cuneate; decussation = internal arcuate.
  • Medial lemniscus (white matter) projects to Ventral Posterolateral Nucleus of Thalamus (VPL), then Somatic Sensory Cortex.
  • Pain and temperature information input for ALS.

Antero Lateral System (ALS)

  • Handles pain and temperature.
  • Two lateral columns with fibers from dorsal horn interneurons.
  • Prior decussation = AWC (Antero Lateral System) tract.
  • ALS approaches medial lemniscus and reaches the VPL of the thalamus, then projecting to the Somatic Sensory Cortex.
  • DCML and ALS both part of Trigeminal System (head / face).
  • projects to Ventral Posteromedial Nucleus of Thalamus (VPM).
  • Lastly to Somatic Sensory Cortex.

Rostral Spinal Cord

  • Key features include the dorsal horn, spinal accessory nucleus, spinal trigeminal tract, posteromarginal nucleus, substantia gelatinosa, intermediate horn (Dorsal nucleus of Clarke).

Key funiculi

  • Posterior funiculus: Gracile fasiculus, Cuneate fasiculus.
  • Lateral funiculus: Rubro-spinal tract, Lateral cortico-spinal tract, Anterolateral system, Spinocerebellar tracts.
  • Anterior funiculus: Anterior cortico-spinal tract, Medial longitudinal fasiculus, Vestibulo-, Tecto-, reticulo-spinal tracts.

Vascular Supply

  • Vertebral artery, basilar artery and its branches supply the brain stem
  • AICA, PICA, SCA all supply the brain stem

Sectional Anatomy (Caudal Medulla)

  • Contains the Gracilis and Cuneatus tracts and nuclei
  • Has a hypoglossal nucleus

Sectional Anatomy (Rostral Medulla)

  • Contains CN nuclei such as Hypoglossal nucleus*, Vestibular nuclei, Cochlear nuclei, Dorsal vagal motor nucleus*, Nucleus ambiguus*, Spinal trigeminal nucleus, and tract
  • Reticular formation is also present

Vascular Syndromes of the Brainstem (Wallenberg – Lateral Medullary Syndrome)

  • Wallenberg syndrome stems from common infarctions of the brainstem specifically from Vertebral & PICA arteries.
  • Damage to Vestibular nuclei result in vertigo, to Trigeminal nuclei (tract) results in decreased facial pain & temperature sensation.
  • Damage to Solitary nucleus can result in decreased taste while damage to the Nucleus ambiguus (IX, X) can cause dysphagia and hoarseness.
  • Other features include decreased body pain and temperature sensation via the anterolateral system (ALS).

Sections

  • Features in pons:
  • Superior medullary velum
  • Superior Cerebellar peduncle
  • Medial Lemniscus
  • Pontine Reticular formation
  • Middle Cerebellar peduncle
  • Ponto-cerebellar fibres
  • Vestibulocochlear nerve (CN VIII)
  • Cortico-spinal Tract
  • Cranial Nerve Nuclei:
  • Principal sensory nucleus, Trigeminal motor nucleus, Mesencephalic nucleus, and tract (in rostral pons only)

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Description

Explore the brainstem's medulla, pons, and cerebellum, including their external anatomy and fiber tracts. Examine the major blood supply, vascular syndromes like lateral and medial medullary, and pontine syndromes. Key anatomical features and exit points of cranial nerves are identified.

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